Sentences with phrase «by endocytic»

Interpretation of the FGF8 morphogen gradient is regulated by endocytic trafficking.

«Non-small cell lung cancers can be sorted in clusters by endocytic changes: Sorting cancer by defective endocytosis genes.»

Not exact matches

Thus, transport of peptide — MHC II complexes by DCs not only accomplishes transfer from late endocytic compartments to the plasma membrane, but does so in a manner that selectively concentrates TCR ligands and costimulatory molecules for T cell contact.

The Loyola study is titled, «Endocytic vesicle rupture is a conserved mechanism of cellular invasion by amyloid proteins.»

However, endocytic waves may be initiated by clathrin through a positive feedback mechanism between clathrin and downstream proteins which includes actin regulating proteins as well as membrane proteins such as PIP3.

The work, led by Assistant Professor Wu Min, showed how a major endocytic pathway mediated by the protein clathrin, was found to commence with periodic traveling waves of clathrin, which were coupled temporally and spatially to downstream cortical actin waves.

The feedback, which couples the initiation of endocytic waves by clathrin to cortical actin waves is analogous to a group of people walking on a wobbly bridge.

Using sensitive live cell imaging, the team noted that endocytic waves initiated by clathrin emerge in some cell populations.

Furthermore, the membrane microdomains induced by BAR domains are expected to function as diffusion barriers, which may for example trap membrane - associated receptor and cargo molecules at the endocytic bud.

Role of the endocytic pathway in the counteraction of BST - 2 by human lentiviral pathogens.

ACAP1 promotes endocytic recycling by recognizing recycling sorting signals.

In this review, we first summarize these contributions by extracellular determinants to the endocytic process.

In collaboration with E. Tartour Group (Georges Pompidou European Hospital, Inserm), the Endocytic Trafficking and Intracellular Delivery Group led by L. Johannes (Inserm / CNRS / Institut Curie) discovered nasal anti-cancer vaccines would stimulate a population...

Thus, the endocytic machinery appears to act as a «sensor gauge» capable of triggering diverse biological processes depending on the intensity of the stimulus received by the cell.

Cell surface receptors can be endocytosed by both clathrin - dependent and clathrin - independent mechanisms, but, as yet, there is no clear understanding of why alternative endocytic routes exist or how receptors are committed to a particular route.