Sentences with phrase «by environmental factors including»

CANCER is often caused by environmental factors including toxic chemicals added to household goods, pesticides and poor air quality, local Green Party MEP Caroline Lucas will tell a Brighton cancer - prevention day this Saturday, February 9th.

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

Such risks, uncertainties and other factors include, without limitation: (1) the effect of economic conditions in the industries and markets in which United Technologies and Rockwell Collins operate in the U.S. and globally and any changes therein, including financial market conditions, fluctuations in commodity prices, interest rates and foreign currency exchange rates, levels of end market demand in construction and in both the commercial and defense segments of the aerospace industry, levels of air travel, financial condition of commercial airlines, the impact of weather conditions and natural disasters and the financial condition of our customers and suppliers; (2) challenges in the development, production, delivery, support, performance and realization of the anticipated benefits of advanced technologies and new products and services; (3) the scope, nature, impact or timing of acquisition and divestiture or restructuring activity, including the pending acquisition of Rockwell Collins, including among other things integration of acquired businesses into United Technologies» existing businesses and realization of synergies and opportunities for growth and innovation; (4) future timing and levels of indebtedness, including indebtedness expected to be incurred by United Technologies in connection with the pending Rockwell Collins acquisition, and capital spending and research and development spending, including in connection with the pending Rockwell Collins acquisition; (5) future availability of credit and factors that may affect such availability, including credit market conditions and our capital structure; (6) the timing and scope of future repurchases of United Technologies» common stock, which may be suspended at any time due to various factors, including market conditions and the level of other investing activities and uses of cash, including in connection with the proposed acquisition of Rockwell; (7) delays and disruption in delivery of materials and services from suppliers; (8) company and customer - directed cost reduction efforts and restructuring costs and savings and other consequences thereof; (9) new business and investment opportunities; (10) our ability to realize the intended benefits of organizational changes; (11) the anticipated benefits of diversification and balance of operations across product lines, regions and industries; (12) the outcome of legal proceedings, investigations and other contingencies; (13) pension plan assumptions and future contributions; (14) the impact of the negotiation of collective bargaining agreements and labor disputes; (15) the effect of changes in political conditions in the U.S. and other countries in which United Technologies and Rockwell Collins operate, including the effect of changes in U.S. trade policies or the U.K.'s pending withdrawal from the EU, on general market conditions, global trade policies and currency exchange rates in the near term and beyond; (16) the effect of changes in tax (including U.S. tax reform enacted on December 22, 2017, which is commonly referred to as the Tax Cuts and Jobs Act of 2017), environmental, regulatory (including among other things import / export) and other laws and regulations in the U.S. and other countries in which United Technologies and Rockwell Collins operate; (17) the ability of United Technologies and Rockwell Collins to receive the required regulatory approvals (and the risk that such approvals may result in the imposition of conditions that could adversely affect the combined company or the expected benefits of the merger) and to satisfy the other conditions to the closing of the pending acquisition on a timely basis or at all; (18) the occurrence of events that may give rise to a right of one or both of United Technologies or Rockwell Collins to terminate the merger agreement, including in circumstances that might require Rockwell Collins to pay a termination fee of $ 695 million to United Technologies or $ 50 million of expense reimbursement; (19) negative effects of the announcement or the completion of the merger on the market price of United Technologies» and / or Rockwell Collins» common stock and / or on their respective financial performance; (20) risks related to Rockwell Collins and United Technologies being restricted in their operation of their businesses while the merger agreement is in effect; (21) risks relating to the value of the United Technologies» shares to be issued in connection with the pending Rockwell acquisition, significant merger costs and / or unknown liabilities; (22) risks associated with third party contracts containing consent and / or other provisions that may be triggered by the Rockwell merger agreement; (23) risks associated with merger - related litigation or appraisal proceedings; and (24) the ability of United Technologies and Rockwell Collins, or the combined company, to retain and hire key personnel.

There are a number of important factors that could cause actual results or events to differ materially from those indicated by such forward - looking statements, including, but not limited to: uncertainties involving interpretation of drilling results, environmental matters, lack of ability to obtain required permitting, equipment breakdown or disruptions, and the other factors described in Paramount's disclosures as filed with the SEC.

Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commfactors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commfactors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commfactors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange CommFactors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.

A small but growing number of countries now have legal requirements for institutional investors to report on how their investment policies and performance are affected by environmental factors, including South Africa and, prospectively, the EU.36 Concern about the risks of a «carbon bubble» — that highly valued fossil fuel assets and investments could be devalued or «stranded» under future, more stringent climate policies — prompted G20 Finance Ministers and Central Bank Governors in April 2015 to ask the Financial Stability Board in Basel to convene an inquiry into how the financial sector can take account of climate - related issues.37

But system selection is not an easy task and complicated by many factors, including production environment, speed, consumable choice, overall equipment efficiency and environmental considerations.

Food choices influence body weight and are shaped by environmental factors, including physical, social and policy, collectively termed the food environment (2).

It is also influenced by some as yet unknown environmental factors (some speculate a susceptibility to certain viruses such as coxsackie, others implicate exposure to certain very specific chemicals, most certainly not included in baby formula).

Creating the problem were several factors: including a formal environmental review process that needed completion after being abandoned by then - governor Eliot Spitzer seven years ago, and a series of carefully wrought but ultimately obtuse statements from the state's Department of Environmental Conservation, in charge of the projects, as well as its own expansion plenvironmental review process that needed completion after being abandoned by then - governor Eliot Spitzer seven years ago, and a series of carefully wrought but ultimately obtuse statements from the state's Department of Environmental Conservation, in charge of the projects, as well as its own expansion plEnvironmental Conservation, in charge of the projects, as well as its own expansion plan's, review.

A two - year study of fracking wells in Los Angeles, conducted by consultants Cardno Entrix and funded by the oil industry, monitored 15 environmental factors before and after fracking, including groundwater chemistry, vibration at the surface and at depth, and methane release.

Susceptibility to chronic inflammatory diseases is determined by immunogenetic and environmental risk factors that include resident microbial communities.

A dust storm that blanketed seven nations in the Middle East in late summer 2015 was caused by climate factors and unusual weather, not human conflict in Syria, concluded researchers including Elie Bou - Zeid, an associate professor of civil and environmental engineering at Princeton.

Yet some cholera scientists — including Rita Colwell, seen by many as a giant in the field — contended that the bacteria had more likely been present in local waters, and that the outbreak had been triggered by a combination of environmental factors.

«Our view is that strandings are likely caused by a complex combination of multiple environmental factors, so we want to include the widest possible range of possible parameters in the follow - up study.»

«GECCO aims to continue to discover additional colorectal cancer - related variants by investigating how genetic variants are modified by other environmental and lifestyle risk factors, including biomarkers as well as how they influence patient treatment response and survival,» Peters said, emphasizing how much further research is required to uncover the specific mechanisms by which genes modulate the intake of certain foods on colorectal cancer risk.

«The range at which a ping can be heard depends on many environmental factors like background noise, changes of water density that cause ping refraction and shielding by seabed features including the wreckage itself,» he warns.

Although the reasons for increased risk to male babies are not known, they could include developmental differences in the growth and function of the placenta, or increased sensitivity of male fetuses to environmental factors experienced by the mother, including obesity, smoking, advanced maternal age, and social deprivation.

This includes cellular mechanisms such as photosynthesis and transpiration, and how plant processes are affected by environmental factors or natural variations.

Kraig and his team, which includes Aya Pusic and Kae Pusic, PhD, discovered that dendritic cells, professional antigen presenting cells of the immune system, can be stimulated by factors released during environmental enrichment to produce exosomes containing microRNAs that improve brain health.

According to the report, that complexity - including the sum of genetic, environmental, and life - stage factors that play a part in the onset of human disease - should now be addressed by bringing together emerging new tools and methods that give scientists insight into the 100,000 chemicals routinely used in commerce but largely untested for health effects.

Our online platform, Project JUST, features brand profiles researched by ethical, social, and environmental factors and a magazine of features including shopper profiles, neighborhood guides and styling posts to help shoppers put their values into action.

Recent research indicates that autism spectrum disorder (ASD) and conditions of similar pathology, like celiac disease and IBD, can be triggered by both intrinsic and extrinsic factors, including environmental toxins like glyphosate, dietary alterations, metabolic status, and intestinal permeability.

Eczema is influenced by several factors, including vitamin D deficiency, allergies (food and environmental), and digestive issues.

Your system can become compromised by many factors, including consumption of processed foods or pesticides, absorptions of unhealthy environmental toxins, illness, medications, or stressful events or lifestyle.

Oxidative stress may be caused by exposure to environmental toxins, pollution, a poor diet, lack of sleep, lack of exercise, and other factors, including inflammatory processes in the body.

How we learn is shaped by a variety of factors, including culture, gender, environmental preferences, and personal strengths or weaknesses.

Investing in the energy sector can be riskier than other types of investment activities because of a range of factors, including price fluctuation caused by real and perceived inflationary trends and political developments, and the cost assumed by energy companies in complying with environmental safety regulations.

Environment Environmental factors believed to contribute to GDV include ingestion of large amounts of food or water by the dog, ingesting food too quickly, too much activity after eating, or delays in emptying the gastrointestinal system.

The bacterium can be «carried» by dogs in their upper respiratory tract (most likely their tonsils) without showing any symptoms of disease and it is likely that, as yet unknown, bacterial, host or environmental factors, possibly including an over-exuberant immune response to the bacteria, are responsible for the severe pneumonia observed in the worst cases.

By noting patterns of cancer development, doctors and veterinarians may become aware of environmental factors that could be causing tumor progression in different species, including humans.»

Notable galleries for 2014 include: Kevin Kavanagh (Dublin), presenting a storytelling series by Sonia Shiel, current ISCP NY artist - in - residence and recipient of Ireland's 2014 Arts Council Project Award; Laura Bulian Gallery (Milan), highlighting career Conceptualist Vyacheslav Akhunov, whose cultural investigations were featured in dOCUMENTA (13) and the 2013 Venice Biennale's Central Asian Pavilion; contemporary Bahamanian art hub Popopstudios (Nassau), spotlighting «everyday» assemblages and mixed - media works by founder John Cox; Frederieke Taylor Gallery (New York), revealing environmental concerns of downtown stalwart Christy Rupp, whose seminal public art projects factored into the 2012 exhibition Come Closer: Art Around the Bowery, 1969 - 1989 at the New Museum; Galerie Heike Strelow (Frankfurt am Main), combining sociopolitical commentary and black humor via Florian Heinke, who curated System of Diplomatic Chaos at Kunstverein Wiesbaden last year; and CONNERSMITH.

Many environmental factors influence the convective life cycle in this region, including orographic, low - level jet, and frontal circulations, surface fluxes, synoptic vertical motions influenced by the Andes, cloud detrainment, and aerosol properties.

The article below from the Tucson Weekly is an important read and contains dire data that is for the most part on target (the climate engineering factor is of course omitted by all parties quoted in the article including Rockefeller funded environmental group 350.org).

One environmental and energy lobbyist with close ties to the White House said the administration had been inhibited by a number of factors, including vacancies in many top policy jobs, an intense early focus on the financial and economic crises, and an unwillingness to alienate business and Congressional leaders with a heavy - handed approach.

Trees are subject to alteration of their growth rate by a wide variety of environmental factors including precipitation, nutrition, insolation, and the co2 level in their immediate environment.

Now, finally, to «the faith of the polar bear» — a species like any other, influenced by a myriad of environmental factors, including bullets and melting sea ice

With the FIT instituted by SB 32, the definition of avoided cost was expanded to include environmental factors, a hazy term that became crucial to clarify when the FIT ran into another law.

For more information about the development and implementation of Legal Services Regulation by the Society, including a discussion of environmental and behavioural factors impacting ethical decision - making by lawyers, refer to «NSBS Journey Toward Transforming the Regulation of Lawyers: Are We on the Right Path?»

The accuracy of the information and data provided by this device and its related software, including heart rate readings, may be affected by factors such as environmental conditions, skin condition, specific activity performed while wearing the device, settings of the device, user configuration / user provided information, placement of the sensor on the wrist, and other end - user interactions.

This includes providing services in circumstances where movement and function are threatened by aging, injury, disease or environmental factors.

Along with environmental factors, emotional competence is also influenced by child factors including cognitive development, temperament, and approach / withdrawal behaviours.

Anxiety sufferers are best helped by understanding emotional conflicts, environmental and genetic factors with treatment that may include talk therapy, CBT, stress reduction techniques, Somatic Experiencing (SE) and EMDR Therapy to target early trauma, memories and present - day distress.

With the caveat in mind that FR - EXT may reflect both genetic and environmental influences, the availability of DNA analysis in the next future will allow us to refine our analyses by including genetic polymorphisms as risk factors.