Sentences with phrase «by epigenetic alterations»
Especially in this vulnerable phase, the kidney is prone to a number of mechanistic changes driven by epigenetic alterations.
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Later in life the genetic material can be changed by epigenetic modifications, i.e. chemical alterations of the DNA the affect the activity of the genes.
Douglas Thomas, associate professor of medicinal chemistry and pharmacognosy at UIC, and co-workers discovered that nitric oxide plays an important role in epigenetics — heritable alterations in gene expression caused by mechanisms other than changes in DNA sequence.
EPIGENETICS AND ANTIBIOTICS «Hidden Switches in the Mind,» by Eric J. Nestler, discusses epigenetic changes — alterations to how genes behave that do not affect the information they contain.
In this study, published in the journal Cell Reports, and led by Dr. Esteban Ballestar (IDIBELL), the comparison of the epigenetic profiles between dendritic cells and myeloid - derived suppressor cells has allowed them to identify the existence of specific epigenetic alterations that associated with the development of myeloid - derived suppressor cells as a result of exposure to prostaglandin E2.
Epigenetics is the study of changes in organisms caused by modifying gene expression — by alcohol, for example — rather than alteration of the genetic code itself.
The term epigenetics, first coined by Conrad Waddington (University of Edinburgh), can be defined as an alteration in gene activity that is mitoti... Read more
The causes of the widespread differential expression of non-coding RNAs in malignant compared with normal cells can be explained by the location of these genes in cancer - associated genomic regions, by epigenetic mechanisms and by alterations in the processing machinery.
A study led by St. Jude Children's Research Hospital shows epigenetic changes that turn genes on and off are as unique as alterations in DNA and may be as important in causing the most common childhood cancer
The variation of the retrotransposons Erv and Iap mRNA amounts and of one of the three imprinted genes analyzed (paternal expressed Zrsr1) suggests that some epigenetic alterations are produced by IVC in the testes of adult mice.
Changes in an epigenetic mechanism that turns expression of genes on and off may be as important as genetic alterations in causing pediatric acute lymphoblastic leukemia (ALL), according to a study led by scientists at St. Jude Children's Research Hospital and published in the June 10 online edition of the Journal of Clinical Investigation.
This paper, Microbiome, inflammation, epigenetic alterations, and mental diseases, sums it up perfectly, reporting that recent findings show that the onset and development of mental diseases such as autism, bipolar disorder, schizophrenia, and depression can not be well described by the one - gene / one - disease approach: