Sentences with phrase «by epigenetic information»
It is now well - established that DNA sequence is complemented by epigenetic information including DNA methylation and histone modifications to program gene expression [24].
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To find out if that was the case, he teamed up with John Goutsias, Ph.D., professor of electrical and computer engineering at the Johns Hopkins Whiting School of Engineering, to find a way to measure this controlled type of randomness, scientifically termed epigenetic stochasticity, by using the information - theoretic concept of Shannon entropy.
«Just as normal cells with the same genome differentiate into many different cell types, a single tumor characterized by specific genetic mutations can contain many different types of cells — stem - like and more differentiated cells — with the difference being rooted in their epigenetic information.
Epigenetic changes do not alter the information encoded in the DNA sequence itself but determine whether and to what extent specific genes are used by cells.
With these results the study by the Max Planck researchers is an important step forward and shows clearly the biological consequences of inherited epigenetic information.
EPIGENETICS AND ANTIBIOTICS «Hidden Switches in the Mind,» by Eric J. Nestler, discusses epigenetic changes — alterations to how genes behave that do not affect the information they contain.
«This suggests that using epigenetics as a biomarker could give you a lot of information about environmental exposures within particular populations that's not captured by genetics,» Zaitlen said.
Through this packaging mechanism, researchers think that histone proteins are the key to regulating access to the genetic information by making different parts of the DNA accessible to factors that express the gene, so - called epigenetic regulation.
Epigenetics provides another way of understanding how genes and environment interact in that there is increasing evidence that gene expression is moderated by the environment in which the organism grows and develops.15 Genetic information is encoded not just in DNA linear sequences but in epigenetic changes in chromatin structure such as DNA methylation or covalent modifications of the DNA - binding proteins.