Sentences with phrase «by epithelial stem cells»
The team's findings may also be relevant to inflammatory disorders that affect other parts of the body, such as the linings of the gut and bowel, which, like the skin, are replenished by epithelial stem cells.
https://www.sciencedaily.com/ Not exact matches
Starting with procedures other research teams had previously worked out to convert iPSCs into keratinocytes, Xu's team demonstrated that by carefully controlling the timing of the growth factors the cells received, they could force the iPSCs to generate large numbers of epithelial stem cells.
This shows hair shafts (arrows) formed by induced pluripotent stem cell - derived epithelial stem cells.
Subsequent studies, as reviewed by Daniels et al. [11] and Lavker and Sun [12] showed that some cells located in the anterior limbus are stem cells which partially differentiate into transient amplifying cells while migrating centrally into the posterior epithelial layer of the cornea.
These epithelial organoid cultures are genetically and phenotypically extremely stable, allowing transplantation of the cultured offspring of a single stem cell, as well as disease modeling by growing organoids directly from diseased patient tissues (45).