Not exact matches
The move is aimed squarely
at making Macy's more nimble as it looks to halt the
erosion of its business
by rivals like Amazon.com (amzn) TJX Cos's (tjx) T.J. Maxx, and Ulta Beauty (ulta).
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven
by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price
erosion caused
by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held
by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or
at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
In this study, the effects of sea level rise (assumed to continue
at present,
at the time of the study, rates, which the authors noted was likely conservative), wave fetch, wind speed and direction were examined and the resultant
erosion rate was estimated for the Western and Eastern shore of Uppands, Port Isobel and Tangier Island
by selecting 10 points along the western and eastern shoreline of all the islands.
Trump's positions are further complicated
by a recent Politico reportthat shows his organization cited global warming as justification to build a coastal structure to prevent
erosion at a golf course in Ireland.
In its view, the company's repeated strategy shifts, missed expectations and what it characterizes as «undue optimism» have resulted in an
erosion of management credibility, and
by extension, shareholder value
at the storied Wall Street firm.
One way of viewing the religious crisis of our time is to see it not in the first instance as a challenge to the intellectual cogency of Christianity, Buddhism, Islam, or other traditions, but as the gradual
erosion, in an ever more complex and technological society, of the feeling of reciprocity with nature, organic interrelatedness with the human community, and sensitive attention to the processes of lived experience where the realities designated
by religious symbols and assertions are actually to be found, if they are found
at all.
The
erosion of the soil in areas that have been abused for their mineral wealth, the pollution of the air where poor people live, are not just facts of nature; what we have is an ethical judgement on the exploitation of natural resources
by the rich
at the expense of the poor.
The
erosion is kept
at bay
by plastic netting which covers the open, sun - baked soil.
Often times, programs just build strength on dys - function
by throwing inappropriate exercises
at athletes, speeding up the
erosion of performance and health.
Dow also pointed to activities taken
by officials
at Folly Beach, South Carolina, an island which has faced
erosion due to changing sea levels.
And early attempts
at farming were plagued
by soil
erosion and cycles of drought that culminated in the 1930s Dust Bowl.
Unlike natural bridges on Earth, which form largely
by erosion from wind and water, these lunar bridges probably formed as a result of an impact in the last billion years, says Mark Robinson, a planetary geologist
at Arizona State University in Tempe and principal investigator for LRO's camera.
More than 50 percent of the reservoir area is affected
by erosion and an additional 500,000 people will need to be relocated,» says Peter Bosshard, policy director
at International Rivers, a dam watchdog group.
Also
at the meeting, Francis McCubbins, a colleague of Agee's
at the University of New Mexico, presented evidence that the rounded appearance of the large faint pebbles suggests
erosion by water or wind.
The rocks had to be 50 million years old, as that is the age of the primates they study, and the land had to be sloped
by at least 5 degrees, so
erosion was likely to have exposed fossils.
The Rosetta spacecraft's first look
at comet 67P / Churyumov — Gerasimenko shows a diverse, complex world, shaped
by eruptions and
erosion, that may hint
at what the solar system was like 4.6 billion years ago.
But a new study published in the Journal of Applied Ecology and led
by University of Pennsylvania doctoral candidate Bianca Charbonneau finds that the invasive plant does have one advantage over its native counterpart, Ammophila breviligulata, or American beach grass: the invasive is better
at preventing
erosion of dunes during big storms.
At Oxia Planum, the clays were covered
by other material for billions of years and then recently uncovered
by wind
erosion.
At September's UN Climate Summit, governments and food traders signed up to the New York Declaration on Forests, which aims to protect the world's forests, in part
by rehabilitating millions of hectares of farmland degraded
by salt,
erosion and overgrazing.
The models predicted
erosion would increase
by at least 100 percent in a quarter of western U.S. watersheds between the start of the 21st century and 2050, a surprisingly large increase in the amount of sediment to enter local streams, according to Sankey.
In addition, two - thirds of western watersheds are projected to experience
at least a 10 percent increase in
erosion by the middle of the 21st century.
This study reveals that the small bone fragments were created during drought periods
by weathering and
erosion of bones disintegrating
at the surface.
These columns of windswept sand — which can cause roadway pileups, eat away
at buildings and machinery, and drive larger processes such as
erosion and dune formation — consisting of many millions of interacting particles propelled
by ever - changing winds.
In a related paper
by Thom, Goldsby and colleagues, published recently in the journal Geophysical Research Letters, the researchers examined patterns of roughness in faults that have become exposed
at Earth's surface due to uplifted plates and
erosion.
To this end, a group of Swiss researchers
at the WSL - Institute for Snow and Avalanche Research (SLF), led
by Prof. Michael Lehning, is exploring mass and momentum fluxes during drifting snow events, pursuing an improved understanding of the link between snow cover
erosion and deposition.
Pictures» ambitious adaptations have performed both outstandingly and consistently
at the box office, with fanbase
erosion offset
by ticket inflation.
The board, a nonprofit consulting organization funded
by individual state membership fees and corporate gifts, aired those views in a 30 - page report citing «widespread
erosion» of student achievement and academic standards throughout the region's 260 colleges and universities and suggesting that such problems
at both the school and college levels threaten the stability of the New England...
(Think: real estate meltdown of 1990 and the
erosion of bank equity, Orange County bankrupted
by mortgage security misunderstandings, threatened Mexican insolvency in 1995, the implosion of Long Term Capital Management in 1998, the technology meltdowns of 2001, Ford Motor Credit
at the wall in October 2002, etc..)
While he supports the Liberal plan, he says the Conservative plan gets
at the root of the problem
by «effectively addressing the
erosion of purchasing power.»
The dune system
at Constantine Bay is in an unfavourable declining condition because of the invasion
by species such as bramble, ivy and sea buckthorn; and
by visitor pressure causing
erosion.
Both DMA and Amon Carter have mounted major shows of Texas art over the past few years — Julian Onderdonk, Loren Mozley, and the current and timely «Alexandre Hogue: The
Erosion Series»
at DMA; and
at the Carter, «Intimate Modernism: Fort Worth Circle Artists in the 1940s in 2008,» and more recently an ongoing gallery devoted to «Texas Regionalism,» soon to be replaced
by «Lone Star Portraits.»
Viewing becomes a spatial, physical experience that compresses the geologic time implied
by the surface details of the stones, a hint of some past process of
erosion or eruption, the photographic moment
at which each object was recorded and the transitory duration in which the images are presented and seen.
God's Dice was a «sculpture play» presented
by Geoffrey Farmer in association with Theatre of
Erosion or I Hate Work That Is Not A Play, a four - week thematic residency that he lead
at Banff Centre in 2010.
Photo: Analia Saban:
Erosion (Staircase), 2012, laser - sculpted acrylic paint on canvas, 48
by 40 inches;
at Tanya Bonakdar.
The Pentagon is closing down three of the 20 NORAD (North American Aerospace Defense Command) early - warning radar sites in northern Alaska because the ground they're built on in some cases is literally crumbling into the Arctic Ocean as a result of
erosion caused
by waves on ice - free waters, military officials
at the U.S. Northern Command tell me.
- the later directly
by putting dust in the ocean (or
erosion and river / wind transport there) or indirectly
by taking up CO2 on land) but
at least the carbonate dissolution could take the place of carbonate dissolution in the ocean (and be more rapid?)
Kivalina, located
at the end of a spit in northwestern Alaska, is one of several villages threatened
by climate - change accelerated coastal
erosion and seal - level rise.
Climate modeller Ken Caldeira believes that if humans keep emitting carbon dioxide into the atmosphere
at the same rate as today,
by 2075 the world's coral reefs will begin to disappear because their rate of natural
erosion will surpass their ability to grow fast enough to keep up.
The backdrop to the renewed interest in asserting territorial claims on the Arctic and Antarctic
by states such as Canada, the United States, Russia and the United Kingdom is that global warming, and in particular the warming of oceans, is leading to accelerating
erosion of the ice mass
at both poles.
Global change, we were taught, occurred slowly and
by commonplace mechanisms: sediment carried
by water, deposited a grain
at a time:
erosion effected
by water and wind, the hardest rocks slowly ground down crystal
by crystal.
Assuming a good bit of this was added after the natural warming cycle was started we are probably looking
at closer to 1200 ppm over the next century or two before C02 levels begin to decrease again as this natural green house locks up carbon primarily in phytoplankton blooms caused
by fertilization from the new large desert regions near the equator and excessive
erosion from very intense storm systems the develop in such a hot house climate.
Likewise when naturally eroding cliffs are armored
at their base
by boulders, the lack of local
erosion can starve adjacent beaches of needed replenishing sediments.
While the HadCM3 - projected mean annual precipitation during 2070 to 2099
at El Reno, Oklahoma, decreased
by 13.6 %, 7.2 %, and 6.2 % for A2, B2, and GGa1, respectively, the predicted
erosion (except for the no - till conservation practice scenario) increased
by 18 - 30 % for A2, remained similar for B2, and increased
by 67 - 82 % for GGa1.
If I asked for a prediction of future beach
erosion, a scientist should not start
by modeling fluid dynamics
at the molecular level.
Polluted runoff from both rural and urban lands increases
erosion and puts public health
at risk
by contaminating drinking water supplies.
At the same time, the start and finish of the criminal justice process are now indefinite and indistinct as a result of the introduction of mass surveillance and the
erosion against «double jeopardy» protections caused
by scientific advances that make it possible to revisit conclusions reached in the distant past.
(«Nielsen»)
at pp. 232 and 254); «an ability to set prices above competitive levels and to maintain them
at that level for a significant period of time without
erosion by new entry or expansion of existing firms» (Tele - Direct
at p. 82); and «the ability to profitably influence price, quality, variety, service, advertising, innovation or other dimensions of competition» (Commissioner of Competition v Canadian Waste Services Holdings Inc, 2001 Comp.