Sentences with phrase «by experimental design»
Off - target effects should be minimized by the experimental design: choose a good sgRNA with the fewest possible off - target effects, control the amount of Cas9 introduced into the cells, and limit the time that Cas9 is present in the cells.
http://www.takarabio.com/ Not exact matches
Passengers can enjoy organic food and drinks, high quality alcoholic beverages — including signature cocktails designed by Paris» Experimental Cocktail Club and craft beer — as well as a comprehensive digital entertainment offering.
It hopes to have a version of its experimental design operating at the Port of Stockton, in California, by early 2018.
The evidence is simply overwhelming and of various different types: the fossil record, the genetic code, experimental confirmations, structures in living organisms which are of no current use but once were, faulty «designs» that are explained by «blind evolution» but that no sentient being would create, predictions that are tested based one the hypothesis it has occurred etc..
First, it is a view that is in part determined by his choice of observation categories, measurement standards, and experimental design.
In 6 to 8 weeks, the Jefferson County Jail will launch an experimental medical program that will administer vivitrol, a medication designed to block the high caused by opiates, to prisoners, who are vulnerable to relapse following their release.
«Our research shows for the first time that classical systems such as artificial spin ice can be designed to demonstrate topological ordered phases, which previously have been found only in quantum conditions,» said Los Alamos National Laboratory physicist Cristiano Nisoli, leader of the theoretical group that collaborated with an experimental group at the University of Illinois at Urbana - Champaign, led by Peter Schiffer (now at Yale University).
Releasing the «personal documents, correspondence, drafts and discussions whose confidentiality is traditionally recognized by the scientific community as essential to encourage the honest and productive exchange and refinement of ideas leading to new scientific insights and improved experimental designs,» according to the brief, would damage the ability of university scientists to exchange ideas freely and make it more difficult for the university to hire top scientists particularly since private universities are not subject to such disclosures.
Though they are found across the animal world from insects to mammals, research into human pheromones has been dogged by flaky experimental designs and dubious commercial endorsements, with the result that the entire field has a whiff of the disreputable about it.
As for theory of mind, Povinelli argues that Clayton's experimental design was inadequate to show it because the birds could have responded to their competitors not by imagining the content of their thinking but just by using rules.
Meanwhile, Stamets began installing experimental mycelial wastewater filtration systems for other farmers (eventually with funding from the county and the state), improving on his initial design by encasing Stropharia spawn and wood chips in burlap sacks and packing them into ditches placed to catch maximum runoff.
The new experimental method, proposed by Prof. Silvia Leoni (UniMi), combined with the computationally extremely sophisticated Monte Carlo shell model developed by the Tokyo University theorists, enabled the design of appropriate, accurate measurements.
SpaceShipOne, created by aerospace engineer and aircraft designer Burt Rutan and financed by Microsoft billionaire Paul Allen, was launched from a traditional airstrip attached to White Knight, a Rutan - designed experimental plane.
The Xbox 360 slimmed down, with its iconic hourglass curves, a look crafted by Astro Studios in San Francisco and Hers Experimental Design Laboratory of Osaka, Japan.
The researchers targeted mTOR with an experimental drug based on a prototype first designed by Shokat, a chemist and an expert in designing molecules to target this type of protein, called a kinase.
Other experimental options include: — AVI - 7537, a drug designed to block viral protein from being made, has shown human tolerability in early studies and could have 100 courses available by early 2015.
By combining a novel design with high - precision techniques for carving semiconductors, the NEC team has developed an experimental transistor with a key feature that's 20 times smaller than in the transistors found on the densest commercially available chips.
Through careful assessment of your experimental design, by speaking with others, and with some perseverance, you should be able to obtain a result.
In 1982 results came in from the Multiple Risk Factors Intervention Trial, which was designed to reduce the risk of coronary heart disease by counseling an experimental group to stop smoking, lower their blood pressure and cut back on saturated fat.
It will provide researchers with a level of detail not typically found in academic research papers, including 3D models, bills of materials, raw experimental data, multimedia step - by - step tutorials, and case studies of various soft robot designs.
«We used a highly controlled experimental design, to ensure that any benefits of mindfulness training were not likely explained by people believing it was a better treatment,» said co-author Dr Tom Freeman (Senior fellow of the Society for the Study of Addiction), who was part of the research team while based at UCL.
«The NIH funding got us all the way from designing the chemical photoswitch to an experimental therapy in the dog,» Flannery says, noting the essential role played by a UC Berkeley interdisciplinary team of chemists, molecular biologists and vision scientists.
The experimental research, conducted by Griffith University's Centre for Quantum Dynamics, aims to help in the design of new molecules for materials science or drug discovery.
«The exciting thing about this study is that it now opens up the RNA world to the ease of experimental design afforded by CRISPR.»
For example, the amygdala is activated by arousal and positive emotions as well, so the key to interpreting such scans is careful experimental design that allows comparison between brain states.
The reviewers suggest starting the manuscript by an overview of the original results and experimental designs, and the reasoning for repeating the two selected experiments.
«We solved multiple problems simultaneously by changing out the electrode, improving the electrolyte and creating good contact and communication between the two materials,» said Haile, who led the development of the concept, guided the experimental design, and supervised the research.
Researchers at Boston University School of Medicine (BUSM) led by Katya Ravid, PhD, designed and tested whether a T2 - weighted MRI could detect bone marrow fibrosis in an experimental model.
Deliberate damage of research work (including damaging, destroying or manipulating experimental designs, equipment, documents, hardware, software, chemicals, or other materials needed by another person to carry out their research);
Throughout the course of this study, the teams compiled an extensive library of experimental and theoretical data including electronic, magnetic, optical, photoelectrochemical, and structural properties, which are now used as feedstock in material genome work and near - term development of superior PEC materials through materials - by - design techniques.
The key benefit of the RBT reactors is their simple and effective design that makes it possible to set up the required irradiation conditions by changing the core size and arrangement; the experimental channels are available as well.
The course will be run by highly experienced scientists of the GMC, and involve presentations and extensive discussions of assays, experimental design and data analyses.
For example, Theme 3 exploits information from Theme 2 to help predict future changes in ocean biogeochemistry and ecosystems, but results from Theme 3 also feed back into Theme 2 by providing critical information on the expected temporal and spatial changes of ocean acidification and thus enable meaningful experimental designs.
This was achieved by measuring genetic variance and heritability of larval fitness - related traits (i.e. size and malformation of shell) through a crossbreeding experimental design and quantitative genetic techniques.
Although we addressed this issue in several ways, including the use of a natural experimental design exploiting the quasi-randomized assignment of patients to hospitalists, it is still possible that unmeasured confounding (eg, residual differences in socioeconomic status of patients that are not explained by patient race / ethnicity, Medicaid eligibility, and household income level) could explain the observed differences in patient outcomes.
That career has been marked by «increasing responsibilities, particularly in the magnet design and manufacturing area, for every experimental fusion device that PPPL has been associated with,» said Mike Williams, associate PPPL director for engineering and infrastructure and a winner of the Fusion Technology Award in 1993.
It will provide researchers with a level of detail not typically found in academic research papers, including 3D models, bills of materials, raw experimental data, multimedia step - by - step tutorials and case studies of various soft robot designs, researchers said.
About the «Human Emulation System» Powered by Organs - On - Chips Technology Based on the Organs - on - Chips technology, Emulate has created a new living Human Emulation System ™ that provides a real - time window into the inner workings of human biology and disease — offering researchers a new technology designed to predict human response with greater precision and detail than today's cell culture or animal - based experimental testing.
Just Google «Gardner Diet Study» and see how a devout vegetarian overcomes any potential confirmatory bias through robust, transparent experimental design - hint the Atkins Diet wins by a large margin.
In a randomized cross-over design, 8 physically active males completed three experimental trials comprising resistance exercise (8 × 5 reps leg extension, 80 % 1 repetition maximum) followed by continuous (30 min, 63 % peak power output (PPO)-RRB- and high intensity interval (10 × 30 s, 110 % PPO) cycling.
Best Picture: (tie) «Gravity» and «Her» Best Director: Alfonso Cuaron, «Gravity» Runner up: Spike Jonze, «Her» Best Actor: Bruce Dern, «Nebraska» Runner up: Chiwetel Ejiofor, «12 Years a Slave» Best Actress: (tie) Cate Blanchett, «Blue Jasmine» and Adele Exarchopoulos, «Blue is the Warmest Color» Best Supporting Actor: (tie) Jared Leto, «Dallas Buyers Club,» James Franco, «Spring Breakers» Best Supporting Actress: Lupita Nyong» o, «12 Years a Slave» Runner up: June Squibb, «Nebraska» Best Foreign Language Film: «Blue Is the Warmest Color» Runner up: «The Great Beauty» Best Animation: «Ernest & Celestine» Runner up: «The Wind Rises» Best Documentary: «Stories We Tell» Runner up: «The Act of Killing» Best Screenplay: Richard Linklater, Ethan Hawke and Julie Delpy, «Before Midnight» Runner up: Spike Jonze, «Her» Best Cinematography: Emmanuel Lubezki, «Gravity» Runner up: Bruno Delbonnel, «Inside Llewyn Davis» Best Editing: Alfonso Cuaron and Mark Sanger, «Gravity» Runner up: Shane Carruth and David Lowery, «Upstream Color» Best Production Design: K.K. Barrett, «Her» Runner up: Jess Gonchor, «Inside Llewyn Davis» Best Music Score: T Bone Burnett, «Inside Llewyn Davis» Runner up: Arcade Fire and Owen Pallett, «Her» Douglas Edwards Independent / Experimental Film / Video Award: «Cabinets of Wonder: Films and a Performance by Charlotte Pryce»
Your experimental design makes sense, but does not rule out the relevant information provided by loading DKCR on both Wii and Wii U.
She is brought back to life by Prof. Jack Crowley (Bruce Abbott) through the use of an experimental drug, as part of a program designed to turn her into an unstoppable warrior.
Masaki Kobayashi's Kwaidan is an anthology inspired by the ghost stories of Lafcadio Hearn, featuring an experimental sound design by the great composer Toru Takemistsu and gorgeous color cinematography by Yoshio Miyajima (Harakiri, The Human Condition).
Blasted by high - volume endorsements of experimental design, researchers may be forgiven for feeling like Manuel Noriega in his 1989 Panama compound.
Whilst we are not looking to become data - reliant, our plan is to track the subjects they select for senior years and how well they perform in specific task types (for example Extended Experimental Investigations) compared to their peers in key Science, Maths and Design subjects, by way of interviews.
Currently, she is the principal investigator of an experimental evaluation of the 4Rs Program — a universal school - based intervention designed to integrate social - emotional learning and literacy development — funded by National Institute of Mental Health, the Institute for Education Sciences at the U.S. Department of Education, as well as by the William T. Grant Foundation.
(*) Programs and practices listed here received support from at least three studies by independent evaluators and / or peer - reviewed publications, using controlled experimental designs and independent outcome measures.
The WWC reviewed 12 studies including one study that met the criteria for rigorous experimental design and one that met the criteria «with reservations,» as determined by the WWC commission.
Teachers are expected to help craft those plans, by designing and testing experimental lessons.