Sentences with phrase «by flaviviruses»

The NS1 protein is produced by flaviviruses, like Zika, and released into the bloodstream of infected patients, where it interacts with the patient's immune system.

Not exact matches

Furthermore, the defects observed are specific to an infection by ZIKV, as other neurotropical viruses of the flavivirus family (West Nile virus, yellow fever,...) did not cause microcephaly, in contrast to Zika virus.

His group, led by first author and Heidelberg postdoctoral fellow Mirko Cortese, also found that Zika and dengue, both flaviviruses, use similar strategies to infect host cells.

Dengue fever is caused by a mosquito - transmitted flavivirus resembling Zika virus.

By analyzing the affected animals, the scientists isolated an aggressive new flavivirus, a class of viruses that includes yellow and dengue fevers — the first flavivirus ever identified in ducks.

Flaviviruses are the cause of diseases spread by mosquitoes (e.g., dengue fever and West Nile fever) and by ticks (e.g., Powassan virus disease and tick - borne encephalitis).

Powassan virus and the closely related deer tick virus are the only flaviviruses known to be spread by ticks in North America.

When the assay was run on patients infected with Zika virus and also on a control group of 540 patients infected by other flaviviruses or other viruses, plus healthy donors, the specificity was 95.9 percent.

Dengue virus and Zika virus are both positive - strand RNA flaviviruses, which means that once a virus particle infects a cell, its RNA genome can be immediately translated by cellular machinery into viral proteins to make new virus particles and spread the infection.

A near - atomic level map of Zika virus shows its structure to be largely similar to that of dengue virus and other flaviviruses, but with a notable difference in one key surface protein, report scientists funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

The difference visualized by the researchers is in a region of the E glycoprotein that flaviviruses may use to attach to some human cells.

Shannon entropy analysis of the NS5 polymerase mature protein revealed that a G374E mutation, in a region that contributes to interferon resistance in other flaviviruses by interfering with JAK - STAT signaling was present in both the Asian and American sequences from the 2007 - 2008 Venezuelan outbreak, but was absent in the sequences from the 2001 Venezuelan outbreak.

Zika virus (ZIKV) is an arbovirus (Flaviviridae family genus flavivirus [1] transmitted by mosquitoes.

From preliminary epidemiology, pathogen isolation, and reproduction of the clinical disease by the isolated virus, BYDV, Koch's postulates were fulfilled, and a new flavivirus causing a serious duck disease was identified.

We performed a systematic investigation, from epidemiology, pathogen isolation, virus characterization, disease reproduction by infection with the isolated virus (fulfilling Koch's postulates), to virus genome sequencing and found that the duck egg drop disease was caused by a new flavivirus, BYD virus, that is closely related to Tembusu virus.

This is the first severe duck disease caused by a zoonotic flavivirus ever reported.

Col. Thomas reminds us, «The WRAIR has been studying flaviviruses for over 100 years, since Walter Reed and his team discovered that yellow fever is transmitted by mosquitoes.»

Dengue Virus (DENV), a flavivirus spread by mosquito vectors, can cause vascular leakage and hemorrhaging.