Sentences with phrase «by gene name»

Not exact matches

The treatment, named Kymriah, was hailed by doctors and the life sciences community as a major advance in medicine and a boon to children and young adults with a certain form of leukemia (the group for whom the gene therapy is approved).

The Craig Scholarship was established in 2016 by the Craig family and is named for Jeanette W. and Eugene «Gene» L. Craig.

And like Evolution, the Theory of Mechanics has been supplanted by more complex and more accurate theories (in the case of Mechanics, both Quantum Mechanics and Relativity have arisen to deal with its flaws; in the case of Evolution, the technical theories - such as gene borrowing and virus - guided genetic drift - do not have catchy names).

In 1986 my research group at the Rockefeller University and another led by Jeffrey Hall of Brandeis University and Michael Rosbash of the Howard Hughes Medical Institute at Brandeis found that the three mutant flies had three different alterations in a single gene named period, or per, which each of our teams had independently isolated two years earlier.

Led by researchers at the Cincinnati Children's Hospital Medical Center Heart Institute, the study demonstrates the gene Gm7325 and its protein — which the scientists named «myomerger» — prompt muscle stem cells to fuse and develop skeletal muscles the body needs to move and survive.

This synthetic genome, named M. genitalium JCVI - 1.0, contains all the genes of wild - type M. genitalium G37 except MG408, which was disrupted by an antibiotic marker to block pathogenicity and to allow for selection.

The vote was conducted by the HUGO Gene Nomenclature Committee, which establishes naming protocols for human genes.

Most of the rechristened genes were identified by geneticists studying the fruit fly; when equivalent genes were later found in the human genome, researchers simply continued using the name of the fruit fly gene to avoid confusion.

By any name, it was the first time researchers had deployed a CRISPR gene drive in a multicelled organism.

But by investigating the DNA sequence around the resistance genes, the team figured out how the resistance genes transfer occurred through a new mechanism named «carry back,» where the pathogen basically has a primitive form of «sex» with the Actinobacterium and takes up its resistance genes after it dies.

«Margery's experiments showed that the NS1 protein can alter expression of Hedgehog target genes on its own, without other viral proteins,» said Bier, professor and newly named holder of the Tata Chancellor's Endowed Professorship in Cell and Developmental Biology.

Research led by Margery Smelkinson found that NS1 modulates the activitiy of a signaling cascade known as the Hedgehog pathway (so named because fruit fly larvae lacking the Hedgehog gene emerge hairless and resemble tiny hedgehogs).

Researchers from BUSM and the University of Cyprus compared the markers on the surface of the cancer cells to gene expression profile of breast tumors deposited by researchers in international public databases and found that a molecule named IL13RA2 (IL13R alpha2) was abundant in metastatic or late - stage BLBC.

The researchers named the method after a fish famous for swimming upstream because it employs an algorithm that can estimate the effect of biases and the expression level of genes as experimental data streams by.

Instead of patiently unraveling life's secrets gene by gene, we can now read them at breakneck speed — thanks in great part to an ingenious, admired, despised, once aimless and now wealthy biologist named Craig Venter.

In separate studies reported in today's issue of Nature, a team led by geneticist Juan Carlos Ispisúa Belmonte at the Salk Institute in La Jolla, California, and another led by geneticist Cliff Tabin at Harvard Medical School found a very similar gene in chicks, named Radical fringe (R - fng), that is active on one side of a budding chick wing.

In the new nomenclature, genetic sequences are labeled «genseq,» followed by a reliability ranking (e.g., 1 if the sequence is from a primary type), followed by the name of the genes from which the sequences were derived (e.g., genseq - 1 16S, COI).

The gene that controls shell thickness, creatively named SHELL, was identified in 2013 by researchers at Orion, Cold Spring Harbor Laboratory in New York and the Malaysian Palm Oil Board (MPOB), a government research institute based near Kuala Lumpur.

The researchers found that the expression of a clock gene named frequency (frq) is controlled by a long non-coding RNA named qrf (frq backwards) − an RNA molecule that is complementary, or antisense, to frq.

These parasites go by many names, including «jumping genes,» «transposable elements» and «transposons.»

Just a few miles down the road, at the IBM Almaden Research Center in San Jose, a computer scientist named Dharmendra Modha recently used 16 digital Blue Gene supercomputer racks to mathematically simulate 55 million neurons connected by 442 billion synapses.

The tomato aficionado might conclude that, given the immense varieties — which go by such fanciful names as Aunt Gertie's Gold and the Green Zebra — heirlooms must have a more diverse and superior set of genes than their grocery store cousins, those run - of - the - mill hybrid varieties such as beefsteak, cherry and plum.

Stem rust, named for the blackening pustules that infect plant stems, caused devastating crop epidemics and famine for centuries before being tamed by fungicides and resistance genes.

Since using the WormBase name of W01A8.1 (MDT - 28) would be misleading, the gene is referred here by the cosmid name W01A8.1, which gives rise to at least three protein isoforms designated W01A8.1 a, W01A8.1 b, and W01A8.1 c from at least seven different transcripts (W01A8.1 a. 1, W01A8.1 a. 2, W01A8.1 b. 1, W01A8.1 b. 2, W01A8.1 b. 3, W01A8.1 c. 1, W01A8.1 c. 2).

In the study, Spradling, with colleagues Michael Buszczak and Shelley Paterno, determined that the fruit fly gene scrawny (so named because of the appearance of mutant adult flies) modifies a specific chromosomal protein, histone H2B, used by cells to package DNA into chromosomes.

Hall and Rosbash then discovered a protein, named PER, that was made by the period gene, and figured out how it worked through a feedback mechanism — its own expression in the cell would cause PER to build up in the nucleus and would eventually effectively shut off the period gene, allowing it to cycle on and off on a daily schedule.

This subtype, named by the authors «senescence - associated macrophages» or SAMs, share some biomarkers of senescent cells by expressing p16 (Ink4a) gene and an enzyme beta - galactosidase.

While WHO failed to mention CRISPR by name, it's hard to imagine ambitious gene - editing endeavors without it.

It's encoded by the gene of the same name.

Abbreviations: Aβ, amyloid β - peptide; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; Ambra1, activating molecule in Beclin -1-regulated autophagy; AMPK, AMP - activated protein kinase; APP, amyloid precursor protein; AR, androgen receptor; Atg, autophagy - related; AV, autophagic vacuole; Bcl, B - cell lymphoma; BH3, Bcl - 2 homology 3; CaMKKβ, Ca2 + - dependent protein kinase kinase β; CHMP2B, charged multivesicular body protein 2B; CMA, chaperone - mediated autophagy; 2 ′ 5 ′ ddA, 2 ′, 5 ′ - dideoxyadenosine; deptor, DEP - domain containing mTOR - interacting protein; DRPLA, dentatorubral pallidoluysian atrophy; 4E - BP1, translation initiation factor 4E - binding protein - 1; Epac, exchange protein directly activated by cAMP; ER, endoplasmic reticulum; ERK1 / 2, extracellular - signal - regulated kinase 1/2; ESCRT, endosomal sorting complex required for transport; FAD, familial AD; FDA, U.S. Food and Drug Administration; FIP200, focal adhesion kinase family - interacting protein of 200 kDa; FoxO3, forkhead box O3; FTD, frontotemporal dementia; FTD3, FTD linked to chromosome 3; GAP, GTPase - activating protein; GR, guanidine retinoid; GSK3, glycogen synthase kinase 3; HD, Huntington's disease; hiPSC, human induced pluripotent stem cell; hVps, mammalian vacuolar protein sorting homologue; IKK, inhibitor of nuclear factor κB kinase; IMPase, inositol monophosphatase; IP3R, Ins (1,4,5) P3 receptor; I1R, imidazoline - 1 receptor; JNK1, c - Jun N - terminal kinase 1; LC3, light chain 3; LD, Lafora disease; L - NAME, NG - nitro - L - arginine methyl ester; LRRK2, leucine - rich repeat kinase 2; MIPS, myo - inositol -1-phosphate synthase; mLST8, mammalian lethal with SEC13 protein 8; MND, motor neuron disease; mTOR, mammalian target of rapamycin; mTORC, mTOR complex; MVB, multivesicular body; NAC, N - acetylcysteine; NBR1, neighbour of BRCA1 gene 1; NOS, nitric oxide synthase; p70S6K, ribosomal protein S6 kinase - 1; PD, Parkinson's disease; PDK1, phosphoinositide - dependent kinase 1; PE, phosphatidylethanolamine; PI3K, phosphoinositide 3 - kinase; PI3KC1a, class Ia PI3K; PI3KC3, class III PI3K; PI3KK, PI3K - related protein kinase; PINK1, PTEN - induced kinase 1; PKA, protein kinase A; PLC, phospholipase C; polyQ, polyglutamine; PS, presenilin; PTEN, phosphatase and tensin homologue deleted from chromosome 10; Rag, Ras - related GTP - binding protein; raptor, regulatory - associated protein of mTOR; Rheb, Ras homologue enriched in brain; rictor, rapamycin - insensitive companion of mTOR; SBMA, spinobulbar muscular atrophy; SCA, spinocerebellar ataxia; SLC, solute carrier; SMER, small - molecule enhancer of rapamycin; SMIR, small - molecule inhibitor of rapamycin; SNARE, N - ethylmaleimide - sensitive factor - attachment protein receptor; SOD1, copper / zinc superoxide dismutase 1; TFEB, transcription factor EB; TOR, target of rapamycin; TSC, tuberous sclerosis complex; ULK1, UNC -51-like kinase 1; UVRAG, UV irradiation resistance - associated gene; VAMP, vesicle - associated membrane protein; v - ATPase, vacuolar H + - ATPase; Vps, vacuolar protein sorting

Besides Affymetrix IDs, searches can be performed with any standard gene name or identifier, as well as by mixing ID types.

Directed by Tony Leondis from a screenplay he co-wrote with Eric Siegel, along with Mike White, The Emoji Movie stars T.J. Miller as an unfiltered and energetic emoji named Gene, with Maya Rudolph as Smiler, James Corden as Hi - 5, Ilana Glazer as the code - breaking emoji Jailbreak, Sofia Vergara as Flamenco Dancer, Steven Wright as Gene's Dad Mel Meh, Jennifer Coolidge as Gene's Mom Mary Meh, Jake T. Austin as Alex, and Patrick Stewart as Poop, of course.

Based on the novel of the same name by Humberto Constantini, this film adaptation from directors Francisco Marquez and Andrea Testa was a Un Certain Regard contender at the 2016 Cannes Film Festival and plays this week at the Gene Siskel Film Center.

There are other movies seen in various stages of production on the Capitol lot, none completely convincing as period pastiche, some funny as send - ups of bad filmmaking: a musical starring an Esther Williams type named DeeAnna Moran (Scarlett Johansson), who refers to her mermaid costume as a «fish ass;» Merrily We Dance, directed by ascot - wearing priss Laurence Laurentz (Ralph Fiennes); bits of Doyle's singing cowboy movies and the latest from Gene Kelly-esque dancer - athlete Burt Gurney (Channing Tatum, showing off a surprisingly passable singing voice).

And since a graphic novel has won the Printz Award before (American Born Chinese by Gene Luen Yang in 2007), the committee may be open to naming another sequential art winner.

This year breaks precedence with the award going to The Shadow Hero (Macmillan / First Second) by Gene Luen Yang «a writer who has made his name in the graphic novel industry, where he wrote and illustrated the first ever graphic novel to be a finalist for the National Book Award [Boxers and Saints]-- and the first ever graphic novel to win the Printz Award [American Born Chinese].»

Since this is a theme restaurant partially owned by Gene Simmons and Paul Stanley of Kiss, we figured there'd be some overpriced Coors Light and TGI Fridays - type - food with clever music - themed names.

Name: Lips: «Rudolph The Red - Nosed Reindeer» Price: 160 Microsoft Points Availability: All Xbox Live Regions Description: Purchase this Premium Song to add «Rudolph The Red - Nosed Reindeer» as performed by Gene Autry to your Lips library.

Supported in part by the Gene R. Cohen Charitable Foundation, the Isabel K. Pease Trust, and friends of the College through the Osher Chair Naming Program.

And like that famed American naturalist before him, much of DeSantis» everyday life is marked with a humility and spirit of volunteerism so rarely seen, yet so very needed.Despite the fact that most folks in town might not know Gene DeSantis by name, the fruits of his labor are nearly everywhere.

The Los Angeles Kiss arena football team noted above is so named because it's owned by Kiss band members Gene Simmons and Paul Stanley.