Sentences with phrase «by genes of interest»

When researchers want to study a specific gene, they often make slight modifications so a special protein tag that produces fluorescent light can attach to the proteins produced by their gene of interest.

Not exact matches

It is, as well, an antidote to Mississippi Burning, a dishonest, award - winning new film in which blacks wait patiently and fearfully in the background for deliverance by two white FBI agents, played by Gene Hackman and Willem Dafoe, who zealously bend the law in the interest of justice — a film one fears will have a profound effect on the way many Americans view their nation in the King Years («The Dream Dafoed,» as the Village Voice put it).

Evolution was not of major interest to most of these biologists, but insofar as they had a theory of it, it was a theory in terms of mutations of individual genes, carried by individual organisms and submitted to natural selection.

In the intervening years, we have come to realize that many of the most interesting and important phenomena in human biology are not caused by any single gene.

Although the study is of interest to researchers by providing an understanding of how FLC moves as it is turned off, it can be applied to any gene in plants or animals.

The audience will learn about the current state of breast cancer research, how data generated by NGS gene panels target variants of interest and have been developed and used in routine laboratory research, and the broader issues of breast cancer education, awareness, and community services.

This form of interference with bacterial gene regulation is also of pharmaceutical interest as it is known that pathogenic bacteria can protect themselves against attack by the immune system and the effect of antibiotics by forming biofilms, for instance on the epithelium of the respiratory system.

A team led by neurogeneticist Rudy Tanzi of Harvard's Massachusetts General Hospital in Boston first became interested in the gene because of a possible connection to the b amyloid protein, which has been implicated in Alzheimer's.

«One of the ways we can reduce the amount of time is by using genetic markers to evaluate which genes are of interest to us.»

Of particular interest were the N - methyl - D - aspartate receptor (NMDAR) genes, which were further studied by qRT — PCR.

(This is why I was so interested in which grandparents she received more of her genes from overall, by the way.)

Many of the downregulated genes are involved in the immune system — an interesting result given the recent finding that D. sechellia can't mount an immune response to an attack by the parasitoid wasp Asobara tabida.

The United Kingdom - based group, led by Julie Williams, Ph.D., Cardiff University School of Medicine, Wales, found the same genes as risk factors and identified a gene variant ABCA7 as an additional gene of interest.

His lab is interested in the regulation of gene expression by mRNA processing in C. elegans and human cells.

One interesting hypothesis by the study authors looks at the role that thyroid hormone plays in regulating the expression of a gene called the amyloid precursor protein (APP), which has a role in Alzheimer's.

By expressing foreign genes in target cell types, they hope to be able to specifically silence or activate cells of interest.

Specifically, they are interested in those genes that are involved in tyrosine phosphorylation — the attachment of a phosphate group (a phosphorous surrounded by oxygen atoms) to distinct sites in protein chains where there is a tyrosine residue.

Promoting survival and proliferation at the single - cell level is critical for expansion of any clonal colonies containing the mutation of interest generated by the gene editing process.

By comparing the whole genome sequence of the lab - cultured resistant strain with a sibling strain that had not been exposed to the drug, they were able to identify several mutations of interest in a number of genes.

He is also interested in genes induced by the interferon response, and his future plans include investigating genes identified in the expression of genome - wide association screens for predisposition to cancers.

One of the more interesting transgenic animals was created by injecting a spider gene into a goat's genome.

These plasmids use fluorescent proteins flanked by long regions of homology to the gene of interest to promote homology directed repair after a CRISPR / Cas9 induced break.

Restricting these differentially expressed genes to ones that changed by at least 4-fold in any comparison, at a stringent p - value cutoff of P < 0.0001, we identified three groups of biologically interesting genes.

Besides information gathered to answer specific experimental questions, as determined by the interests of individual partners [35]--[41], the collective data offered the opportunity to search for coordinated gene expression patterns in a systematic exploration of the mouse ES transcriptome under a battery of different experimental settings, thus minimizing possible site - specific artifacts.

We aim to develop a system that links gene discovery to signaling pathways and eventually to set up animal models of disease by manipulating genes of interest through mouse genetics.

The research spending comes at a time of growing interest in synthetic biology, particularly surrounding the potential presented by new gene - editing techniques.

These mice were created and deposited by The Pleiades Promoter Project (Centre for Molecular Medicine and Therapeutics, University of British Columbia); their goal is to generate 160 fully characterized, human DNA promoters of less than 4 kb (MiniPromoters) to drive gene expression in defined brain regions of therapeutic interest for studying disorders such as Alzheimer's disease, Parkinson's disease, Huntington's disease, Amyotrophic Lateral Sclerosis (Lou Gehrig's disease), Multiple Sclerosis, Spinocerebellar Ataxia, Depression, Autism, and Cancer.

Although experimental mammalian genetics with the use of ES cells and the techniques pioneered by my co-awardees is now well founded and used, there is still much to be learned and much interesting research in store about what genes really do in the context of the real biology of the whole organism in a complex environment.

The Tol2 Gateway - Compatible Toolbox is based on the original Tol2kit generated by the Chi - Bin Chien lab (Kwan et al., 2007) and includes four promoters, six fluorophores with nonoverlapping emission spectra (N - and C - terminal tags for mTagBFP, TagRFPt, EGFP, mVenus, mCerulean3, mKOFP2) and empty vectors that have standard cloning sites or gateway compatible cloning sites for easy cloning of your genes of interest.

For instance, in choosing links for the 2007 Michael L. Printz Award book American Born Chinese by Gene Yang, I was able to select graphic novels and books about graphic novels, for readers who are interested in the format, as well as historical fiction about the lives of Chinese immigrants in North America and contemporary novels about teens living with immigrant parents.

As a mother of twins, and as a doctor, I've long been interested in how much of our lives is dictated by the genes we land here with — a blueprint over which we have no control.

If you have good genes and a healthy lifestyle, your increased long life means you may be negatively impacted by the new normal of low interest rates and the lack of a real pension for life.

Results of this first molecular genetic study of infant attachment [86, 96] seem to have transformed the attachment field by increasing interest in studying genetic and gene - environment interaction effects.