Sentences with phrase «by genetic mutations»

Breast cancer is caused by a genetic mutation in the DNA of breast cancer cells.

The protein that is involved in the proper formation of bone is in some way affected by a genetic mutation.

Most of the functions that allow cancer cells to flourish are made possible by genetic mutations.

In later experiments, she investigated whether the treatment was also effective in models of generalized childhood epilepsy caused by genetic mutations.

Sickle cell disease is a group of inherited blood disorders caused by genetic mutations in the HBB gene, resulting in abnormal hemoglobin, the iron - containing protein that normally allows blood cells to carry oxygen.

Muscular dystrophy, a disease caused by a genetic mutation on the X chromosome, primarily affects boys and comes in several varieties.

Animal studies have also found that a stress to a parent, such as exposing a pregnant mouse to toxic chemicals or mildly shocking a mouse father to make it fear an odor, can result in effects such as infertility or changes in behavior that persist for two generations or more yet can't be explained by genetic mutations.

«These findings suggest that it may be possible to treat neurological disorders caused by genetic mutations through an efficient and precision medicine - style approach.»

The research just published proposes that the normal biology of mRNA regulation in neurons, in which RNA is generally silenced and only activated in the correct place and time, makes it susceptible to both age - related decline and disturbance by genetic mutation.

The lab has shown that when NMDAR function is impaired by a genetic mutation, they can recreate, in the mouse, the structural, neurochemical, and functional alterations in the brain that are characteristic of schizophrenia — for example, cognitive and memory impairments for which there are currently no effective treatments.

Some of the same biochemical players that protect the body by controlling the inflammation response of cells can also be hijacked by genetic mutations involved in the development of cancer.

The adaptation of these culture systems to miniaturized formats suitable for High Throughput Screening combined to the development of image - based automated phenotypical analysis help revealing any alteration induced by a genetic mutation responsible for a neurodevelopmental disorder.

12/19/2007 Study Details Atomic Structure of Proteins Altered in Autism A new study by an international group of scientists describes in atomic detail a protein complex that is affected by genetic mutations implicated in autism spectrum disorders.

There are two general types of resistance genes found in wheat: Race - specific genes confer a high - level of resistance to specific strains of leaf rust but can be easily overcome by genetic mutation in pathogen populations, while slow rusting (APR) resistance provides partial resistance to a broad spectrum of races, but is typically effective only at the adult stage of plant growth.

This presents a significant advance in understanding that circuits in the brain regulate amyloid - beta protein composition, showing that Alzheimer's is also driven by physiological mechanisms and just by genetic mutations.

Other common causes of megalencephaly include Rasopathies, a group of diseases caused by genetic mutations which lead to an upregulation of the mitogen - activated protein kinase (Ras / MAPK) pathway [31].

Multifactorial genetic disorders occur when more than one gene is affected by a genetic mutation.

Scientists, including speaker Petter Stromme of the University of Oslo, have found that the disorder is caused by a genetic mutation in the SLC9A6 gene on the X chromosome.

Sickle cell anemia is caused by a genetic mutation that leads to «sickling» of the red blood cells.

«Too much of this building block due to SAMHD1 deficiency caused by genetic mutations can lead to autoimmune diseases and help cancerous tumors grow.

It was previously shown by others that a rare disease called generalized pustular psoriasis (in which the skin erupts into pustules) was caused by a genetic mutation that resulted in unrestrained activity of a protein normally produced in our skin, called IL - 36.

The disease is caused by a genetic mutation that leads to abnormal clumps of protein in the brain, eventually resulting in the atrophy and death of nerve cells.

Their work, published online July 8 by the journal Science Translational Medicine, could pave the way for gene therapy in people with hearing loss caused by genetic mutations.

Last spring Laura Murphy, then 28 years old, went to a doctor to find out if a harmless flap of skin she had always had on the back of her neck was caused by a genetic mutation.

«This study is exciting because it shows that changes within the body can affect the progression of a disorder caused by a genetic mutation,» said Jim I. Koenig, Ph.D., program director at NINDS.

Diseases caused by genetic mutations can be challenging to diagnose.

The disease is caused by a genetic mutation that prevents a protein required to keep muscle cells intact from being produced.

It is caused by genetic mutations that result in the loss of the dystrophin protein, leading to progressive muscle weakness and death by the second or third decade of life.

But unlike Rosenbloom's other patients, a workup showed they were not lacking growth hormone; instead, they had a rare form of dwarfism known as Laron syndrome, caused by a genetic mutation that prevents the body from responding to growth hormone.

«We know that the majority of cancers are caused by genetic mutations.

Spinal muscular atrophy is caused by a genetic mutation that triggers the loss of spinal cord motor neurons — neurons that help control the body's movements.

Transplanted hearts lasted in four groups of mice as follows: • 21 days: mice with hyperlipidemia caused by a genetic mutation of apolipoprotein E (ApoE) placed on a high - fat diet • 51 days: healthy mice placed on a high - fat diet leading to hyperlipidemia • 61 days: mice with hyperlipidemia caused by a genetic mutation of ApoE on a lower - fat diet • More than 100 days: healthy mice placed on a lower - fat diet

It is caused by a genetic mutation, which Dr. Baraban's group was able to introduce into the zebrafish to cause epilepsy.

Its onset hits at the fetal stage and is caused by genetic mutations.

Diseases brought on by genetic mutations in our mitochondria are referred to, sensibly, as mitochondrial diseases.

Tuberous sclerosis is caused by a genetic mutation that either is inherited from a parent or acquired during development before a children is born.

Although cancer that is caused by a genetic mutation can be treated, the genetic mutation itself is either permanent or «really hard to fix,» says Joyce Ohm, PhD, Department of Cancer Genetics and Genomics at Roswell Park.

By contrast, the congenital sideroblastic anemias (CSAs) are inherited diseases caused by genetic mutations that are present at birth in all the cells.

CJD can be caused by genetic mutations, by exposure to contaminated foods (as with so - called mad cow disease) or even, in rare cases, from accidental exposures during medical procedures, such as surgery or other invasive treatments.

Only about 5 to 10 percent of all cancers are thought to be caused by genetic mutations, according -LSB-...]

Only about 5 to 10 percent of all cancers are thought to be caused by genetic mutations, according to the American Cancer Society.

And since cancer is caused by genetic mutations, it's no surprise that green tea may have anti-cancer properties.

The short - legged trait is caused by a genetic mutation.

«It can be caused by structural defects in the brain and spinal cord that occur during fetal development», when the mesenchymal tissue is forming, «possibly caused by genetic mutations or lack of proper vitamins or nutrients in the maternal diet.»

Von Willebrand disease is caused by genetic mutations that impair the synthesis, release, function or stability of von Willebrand factor.

Von Willebrand Disease is caused by genetic mutations that interfere with the production or function of the von Willebrand factor protein.