In just one example, short - chain fatty acids — the metabolic by - products of the fermentation of fiber that are produced
by the gut microbes — are important for numerous aspects of health, including the maintenance of optimal metabolic well - being, mood, and cognition, and the health of the immune system.
** Viruses Worldwide Battled
by Gut Microbes.
a short chain fatty acid and by - product of the digestion of dietary fiber
by gut microbes.
One of the compounds in pomegranate is transformed
by gut microbes into a molecule called urolithin A, which causes mitophagy a process important for the renewal of mitochondria.
They are not putting themselves into a «nutritional» state of starvation by restricting protein along with carbohydrate, in order to consume more micronutrient bankrupt fat, without even resistant, fermentable fibers to ensure vitamin - synthesis
by gut microbes — just to ensure keto - hocus - pocus long term.
The important bit:» Finley said these were among the compounds that were poorly digested, yet acted upon
by gut microbes.
Two common factors emerged in urine that had a better ability to resist bacterial growth: it had a high pH — one that's more alkaline, in other words — and higher levels of certain metabolites formed
by gut microbes.
In the current study, being published in the journal Science Translational Medicine, the international interdisciplinary research team demonstrates that the transport of molecules across the blood - brain barrier can be modulated
by gut microbes — which therefore play an important role in the protection of the brain.
Eggs, beef, pork and fish are the primary sources of carnitine and choline — compounds that are converted
by gut microbes into trimethylamine, which is then processed by the liver and released into the circulation as TMAO.
Is it an enzyme produced by the worm itself or
by its gut microbes?
Bananas are also quite rich in fibre and resistant starch, which are loved
by your gut microbes, keeping all those friendly bacteria happy, healthy and fed.
Our laboratory is focused on identifying molecular mechanisms
by gut microbe - derived metabolites promote human liver disease including both non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD).
Not exact matches
Diuretics can hinder the absorption of vital nutrients
by the
gut and can lead to the unnecessary loss of healthy
gut microbes.
In a study published in the Canadian Medical Association Journal, researchers led
by Anita Kozyrskyj found that babies born
by C - section harbored a different set of
microbes in their digestive tracts than those born vaginally, and that infants who were breast - fed had a different recipe of bacteria in their
guts than those who were given formula.
«Chronic inflammation of the intestine is thought to be caused
by abnormal interactions between
gut microbes, intestinal epithelial cells and the immune system, but so far it has been impossible to determine how each of these factors contribute to the development of intestinal bowel disease,» said Hyun Jung Kim, Ph.D., former Wyss Technology Development Fellow and first author on the study, speaking about the limitations of conventional in vitro and animal models of bacterial overgrowth and inflammation of the intestines.
«Jet lag can cause obesity
by disrupting the daily rhythms of
gut microbes.»
A study published
by Cell Press October 16th in Cell now reveals that
gut microbes in mice and humans have circadian rhythms that are controlled
by the biological clock of the host in which they reside.
Now research in rodents suggests that
gut microbes may alter the inventory of microRNAs — molecules that help keep cells in working order
by managing protein production — in brain regions involved in controlling anxiety.
«GI side effects of chemotherapy reduced in mice
by targeting
gut microbes.»
By contrast, mice raised in the germ - free cages showed worse motor symptoms when they either were treated with microbial metabolites called short - chain fatty acids or received fecal transplants of
gut microbes from patients with Parkinson's disease.
By contrast, the HMS team homed in on one
microbe at a time and its effects on nearly all immune cells and intestinal genes, an approach that offers a more precise understanding of the interplay between individual
gut microbes and their hosts.
By chemically removing the
gut microbiome in zebrafish in the lab and then repopulating the
gut with two to three bacterial species, University of Oregon biologist Karen Guillemin has shown that certain
microbes are especially skilled at suppressing the host immune system and preventing inflammation — a discovery she thinks may have implications for human health.
Human milk's most important role could be preventing infant disease and boosting immunity
by cultivating a balance of
microbes in the
gut and the rest of the body, a kind of internal ecosystem called the microbiome.
Taken together, the results suggest that
gut microbes exacerbate motor symptoms
by creating an environment that could favor the accumulation of misfolded protein aggregates.
Early results show that the capsules have cured 32 people infected with drug - resistant Clostridium difficile, a dangerous
microbe that installs itself in the
gut and causes inflammation marked
by diarrhea, cramping and pain.Thomas Louie, an infectious disease physician at the University of Calgary in Alberta, presented the data on October 3 at ID Week, a meeting of infectious disease specialists.
And perhaps surprisingly, these molecules are not produced
by human cells, but
by a person's
gut microbes as they process food in the diet.
In broccoli sprouts, its precursor, glucoraphanin, exists and is converted into sulforaphane
by myrosinase contained in broccoli itself and produced
by microbes in the
gut.
But in those with immune systems weakened
by age, chemotherapy or antibiotics that wipe out their «lawn» of beneficial intestinal
microbes, C. difficile can get a foothold and cause changes that damage the
gut.
By not aiming to kill the pathogen with antibiotics, scientists were able to avoid wiping out sizeable numbers of beneficial
gut microbes.
Levy is fond of citing a French study showing that when people whose
guts were plagued
by resistant E. coli ate only sterilized food, the nature of the prevailing
microbes changed.
By comparing how
gut microbes from human vegetarians and grass - grazing baboons digest different diets, researchers have shown that ancestral human diets, so called «paleo» diets, did not necessarily result in better appetite suppression.
This shows that the
microbes in our
guts are determined in part
by our evolutionary history, not just external factors like diet, medicine and geography.
Yet in captivity, they all lost their distinctive
microbes and ended up being dominated
by the same bacteria that dominate our human
guts — species of Bacteroides and Prevotella.
To test whether a partial loss of plant - derived dietary fiber would result in a partial loss of native
gut microbes, the authors also collected fecal samples from a semi-captive population of red - shanked doucs who lived in a sanctuary and received about half of the normal variety of plants eaten
by wild doucs.
Dr. Claire de La Serre and colleagues found that this negative effect may be reversed
by manipulating the
gut microbes.
Working with mice bred to have no
gut microbes of their own, Gordon's graduate student Laura Blanton fed them a mash of the same food typically eaten
by Malawian children.
To better understand how changes in diet, lifestyle, and exposure to modern medicine affect primates»
guts, a team of researchers led
by University of Minnesota computer science and engineering professor Dan Knights, veterinary medicine professor Tim Johnson, and veterinary medicine Ph.D. student Jonathan Clayton, used DNA sequencing to study the
gut microbes of multiple non-human primates species in the wild and in captivity as a model for studying the effects of emigration and lifestyle changes.
Diverse
gut microbes are also thought to keep pathogens at bay simply
by occupying a range of habitable niches inside us, leaving no room for anything else to grow.
A dose of antibiotics abolished these preferences — the flies went back to mating without regard to diet — suggesting that it was changes in
gut microbes brought about
by diet, and not diet alone, that drove the change.
This approach is also being used to reverse engineer even more complex
gut environments
by integrating other cell types, such as immune cells, neuronal cells, and commensal
microbes into the device.
In the journal Nature, Manuela Raffatellu, associate professor of microbiology & molecular genetics, and colleagues provide the first evidence that small protein molecules called microcins, produced
by beneficial
gut microbes, play a critical part in blocking certain illness - causing bacteria in inflamed intestines.
«Proteins secreted
by beneficial
gut microbes shown to inhibit salmonella, invasive E. coli: Study finds that microcins help block illness - causing bacteria in inflamed intestines.»
In a recent paper in the journal Trends in Ecology and Evolution, Shapira, who studies the
gut microbes of the nematode C. elegans, reviews evidence that demonstrates how microbiotas affect and contribute to host evolution, either
by evolving along with the host, or
by stepping in at critical moments to help the host adapt to a new environmental challenge.
Rawls said many genes that are activated
by microbes in the mouse
gut are similarly responsive in the fish
gut.
Supplementation with probiotics can improve a person's
gut health, but the benefits are often fleeting, and colonization
by the probiotic's good
microbes usually doesn't last.
Their communication system is mediated, at least in part,
by the presence of certain
gut microbes.
By the time the babies were a year old, though, the researchers couldn't detect any distinct differences between the
gut microbes of 22 babies at high risk of asthma and 297 babies at low risk.
Scientists increasingly realize the importance of
gut and other
microbes to our health and well - being, but one University of California, Berkeley, biologist is asking whether these
microbes — our microbiota — might also have played a role in shaping who we are
by steering evolution.
A new study in mice, conducted
by researchers at Sweden's Karolinska Institutet together with colleagues in Singapore and the United States, shows that our natural
gut - residing
microbes can influence the integrity of the blood - brain barrier, which protects the brain from harmful substances in the blood.
Getting «informed consent» from the Matses to gather their fecal samples, which are the best source of bacteria from the gastrointestinal (GI) tract, was a challenge, Lewis says, so the anthropologists gave the Matses a crash course in bacterial biology
by showing them
gut microbes under microscope.