Not exact matches
The study also showed that the main activator of artemisinin is haem, a specific iron - containing compound, either biosynthesised
by the parasite at its early developmental ring stage, or derived from
haemoglobin digestion in the later stages.
Thalassaemia is the world's most common genetic disease and is caused
by mutations in one or both of the genes that code for
haemoglobin.
They looked for those that were triggered to release oxygen
by bicarbonate ions, and found that human
haemoglobin behaved like its counterpart in crocodiles if it contained a particular sequence of just 12 amino acids from the crocodile's
haemoglobin.
Haemoglobin is produced
by erythroblasts, cells in the bone marrow that mature into red blood cells.
Their paper «Root Effect
Haemoglobin May Have Evolved to Enhance General Tissue Oxygen Delivery»
by Jodie L. Rummer, David J. McKenzie, Alessio Innocenti, Claudiu T. Supuran and Colin J. Brauner appears in the 14 June 2013 issue of the journal Science.
β - thalassemia is an inherited disorder caused
by mutations in the β - globin chain of
haemoglobin that lead to... Continue reading Animal research: At the forefront of modern medicine
«Results presented
by [CRISPR Therapeutics] at a haematology meeting showed that the method dramatically increased foetal
haemoglobin in β - Thalassemia patients» cells.
Since plasmepsins are involved in the parasite's
haemoglobin - to - haemozoin conversion pathway, targeted
by related antimalarials, plasmepsin 2 - 3 amplification probably mediates piperaquine resistance.
Dr Rosedale's second cite is actually to a commentary: ««Normal» blood glucose and coronary risk» in the British Medical Journal, http://pmid.us/11141131, commenting on a paper
by Khaw et al, «Glycated
haemoglobin, diabetes, and mortality in men in Norfolk cohort of european prospective investigation of cancer and nutrition (EPIC - Norfolk),» http://pmid.us/11141143.
He purchases
haemoglobin sub-rosa from a hospital hand played
by Jeffrey Wright, amasses recherché musical instruments via Ian (a wonderful Anton Yelchin), including a Gretsch Chet Atkins, and the nights go
by.
My understanding is that Cyanide poisoning operates
by saturating the Oxygen sites in
Haemoglobin with CN; which prevents it from carrying Oxygen to the cells.