Ellagic acid metabolism
by human gut microbiota: consistent observation of three urolithin phenotypes in intervention trials, independent of food source, age, and health status.
Not exact matches
As noted
by Dr. Vicki Ellingrod — the Chair of this session, «Current state - of - the - art research in both animal models as well as
humans point to the link between the
gut microbiota and mood and anxiety models, as well as the potential for psychiatric medications to directly affect the
gut microbiome.»
In addition, cohousing coprophagic mice harboring transplanted
microbiota from discordant pairs provides an opportunity to determine which bacterial taxa invade the
gut communities of cage mates, how invasion correlates with host phenotypes, and how invasion and microbial niche are affected
by human diets.
A deep global analysis of the
gut microbiota composition was done
by phylogenetic microarray analysis using a
Human Intestinal Tract Chip (HITChip), an analytical device designed specifically for studying
gut bacteria.
The findings illuminate the specialized roles played
by key members of the vast microbial community living in the
human gut, and could inform the development of tailored
microbiota transplants to improve intestinal health after antibiotic use or illness.
Spurred
by this finding, Littman's team examined the
gut microbiota in patients with rheumatoid arthritis, a debilitating autoimmune disease, and found a much higher proportion of patients than healthy individuals who harbored the
human intestinal bacterium Prevotella copri.
A few interesting articles in early life
human microbiome, plus: A comparison between Staphylococcus epidermidis commensal and pathogenic lineages from the skin of healthy individuals living in North American and India; A new tool to reconstruct microbial genome - scale metabolic models (GSMMs) from their genome sequence; The seasonal changes in Amazon rainforest soil microbiome are associated with changes in the canopy; A specific class of chemicals secreted
by birds modulates their feather microbiome; chronic stress alters
gut microbiota and triggers a specific immune response in a mouse model of colitis; and evidence that the short chain fatty acids profile in the
gut reflects the impact of dietary fibre on the microbiome using the PolyFermS continuous intestinal fermentation model.
The great news is that
by adding fermented veggies into your foods, you are changing your
gut health for better: «the composition of the
gut microbiota has been shown to differ in lean and obese
humans and animals and to change rapidly in response to dietary factors.
Hence, a lot of necessary neurotransmitters in the body are generated
by the
gut microbiota, exerting influence on the
human body including the brain, among which many neurotransmitters in the
human gut microbiota are also critical molecules.»
Nutrition - derived bioactive metabolites produced
by gut microbiota and their potential impact on
human health
The delicate balance between the
human microbiome and the development of psychopathologies is particularly interesting given the ease with which the microbiome can be altered
by external factors, such as diet, 23 exposure to antimicrobials24, 25 or disrupted sleep patterns.26 For example, a link between antibiotic exposure and altered brain function is well evidenced
by the psychiatric side - effects of antibiotics, which range from anxiety and panic to major depression, psychosis and delirium.1 A recent large population study reported that treatment with a single antibiotic course was associated with an increased risk for depression and anxiety, rising with multiple exposures.27 Bercik et al. 28 showed that oral administration of non-absorbable antimicrobials transiently altered the composition of the
gut microbiota in adult mice and increased exploratory behaviour and hippocampal expression of brain - derived neurotrophic factor (BDNF), while intraperitoneal administration had no effect on behaviour.
Artificial sweeteners have been shown to cause glucose intolerance in mice
by altering
gut microbiota and are associated with dysbiosis and glucose intolerance in
humans.