Project: Pre-clinical Assessment of Human Retinal Ganglion Cell Neuroprotection
by Human Stem Cells: Efficacy and Mechanism.
A glomerulus - on - a-chip lined
by human stem cell - derived kidney cells could help model patient - specific kidney diseases and guide therapeutic discovery
Not exact matches
ESCR scientists are mounting a furious political assault against the lawsuit, currently back in Royce Lamberth's court urging that
human embryonic
stem cell research continue to be funded
by the Feds, hoping to pressure the judge to see it their way.
«Motivated in large part
by their religious traditions of protecting the vulnerable and serving «the least of these,» as Jesus instructed his followers to do in the Gospel of Matthew,» writes Eric Marrapodi, «World Relief and other Christian agencies like the Salvation Army are stepping up efforts and working with law enforcement to
stem the flow of
human trafficking, which includes sex trafficking and labor trafficking.»
-- Offer support FIRST to those who have suffered the abuse that
stemmed from or was abetted
by troublesome theology (whether it be formal volunteering, donating money or goods or even just validating that a victim is not crazy, not sinful and is a worth
human being and that their abuser was in the wrong.
The dropping of the atomic bomb, however, and the killing of birdlife
by DDT, documented
by Rachel Carson's Silent Spring, introduced a new problem: the presence of totally unpredicted (and probably unpredictable) harmful effects on the environment and on
human life
stemming from actions taken specifically to produce certain benefits.
Stem cell research using
human embryos might mean new mornings for people like these — people you and I know
by name.
The ANT - OAR proposal represent a scientifically and morally sound means of obtaining
human pluripotent
stem cells that does not compromise either the science or the deeply held moral convictions of those who oppose the destructive use of
human embryos for research» which is a creative approach that can be embraced
by both the anything - goes camp and the nothing - goes.
As we read this history, the furor over
stem cells was fueled
by numerous factors: the near - universal
human desire for magic; patients» desperation in the face of illness and their hope for cures; the belief that biology can now do anything; the reluctance of scientists to accept any limits (particularly moral limits) on their research; the impact of big money from biotech stocks, patents, and federal funding; the willingness of America's elite class to use every means possible to discredit religion in general; and the need to protect the unlimited abortion license
by accepting no protections of unborn
human life.
Examples are 9/11 hijackings, The holding back of
stem cell research that could save countless
human lives, Aids being spread due to religious opposition to the use of condoms, Christians legally fighting this year to teach over 1 million young girls in America that they must always be obedient to men, the eroding of child protection laws in America
by Christians, for so called faith based healing alternatives that place children's health and safety at risk, burning of witches, the crusades, The Nazi belief that the Aryans were god's chosen to rule the world, etc... But who cares about evidence in the real world when we have our imaginations and delusions about gods with no evidence of them existing.
In both cases individual members may exercise some dominance over others, in particular
by altering the patterns guiding further growth and development, but the social coordination
stems from basic patterns embodied in the genetic makeup of the plant cells and in the laws and traditions of
human culture.
This question has been the topic of considerable legal and social debate over the years since the Supreme Court's Roe v. Wade decision» debate that has only been intensified
by the recent controversies over
human embryonic
stem cells and
human....
He decreed that the case brought
by researchers Drs James Sherley and Theresa Deisher, along with a number of Christian groups including the Christian Medical Association, should be heard; and ordered an injunction temporarily blocking federal funding allocated for
human - embryonic -
stem - cell research.
This way of understanding the
human person, which
stems from the unique dignity of the person created in the image and likeness of God (Gen 1:26 - 27) and called to eternal redemption in Christ, is rooted in revelation, but it can be appreciated or grasped as true even
by those who do not share our faith, on the basis of natural moral law.6
America's exceptional history as the only nation in the world with two centuries of political continuity
stems from its people's love for individual rights, which they hold to be inalienable because they are granted
by a power that no
human agency dare oppose.
The field of PTSD growth potential,
stemming from positive psychology, offers a much needed perspective of the resiliency of the
human spirit to not only survive trauma, but to somehow transform the adversity encountered
by the event, into self - growth.
One of the best talks of this conference was given
by Dr. Renee Reijo Pera, Professor and Director of the Center for
Human Embryonic
Stem Cell Research at Stanford University.
The
Human Rights Activist maintained that the State PCRC was ready to give needed support and cooperation to the State Police Command
by serving as helping hands in
stemming the tide of insecurity and other forms of illegality.
Frankenbunnies Embryos made
by Chinese researchers who fused
human skin cells with rabbit eggs, hoping to create a source of
stem cells.
Members interested in this area of work develop
human rights ‐ related activities and services for the science, technology, engineering and mathematics (
STEM) community to build the commitment and capacity of professional associations to engage meaningfully in
human rights
by leveraging the experience of their members.
Elsewhere, the Directorate for Education and
Human Resources (EHR), which funds a wide array of
STEM programs, would be reduced
by $ 119 million or 13.6 percent below last year enacted, with a particularly sharp cut to graduate research fellowships.
Faced with an often - hostile Congress, Obama enacted many of his signature policies
by executive order — from reversing restrictions on research with
human embryonic
stem cells to helping communities prepare for climate change.
Geron was bigger and better funded than ACT, and it was the first company to be approved
by the US Food and Drug Administration (FDA) to test a therapy in
humans based on embryonic
stem (ES) cells.
They recoated the insides of the blood vessels
by flowing
human stem cells through the tubes attached to the artery and vein.
Oliver Brüstle, director of the Institute of Reconstructive Neurobiology at the University of Bonn, Germany, who had a patent on a method for generating neurons from
human embryonic
stem cells rejected
by the court, called the ruling «the worst possible outcome», and «a disaster for Europe».
Researchers at Geron, meanwhile, had successfully derived neurons from
human embryonic
stem cells and were pursuing research that would eventually look to repair the damage caused
by spinal - cord injuries, a possible use for embryonic
stem cells that was much touted at the time.
«Our work illustrates that this exquisite control mechanism — regulated
by PUS7 and pseudouridine — is critical to adjusting the amount of proteins needed for
human stem cells to grow and produce blood,» says Cristian Bellodi.
Using
human fetal «mini-brains» grown in 3 - D cultures, scientists determined that a specific protein produced
by the Zika virus changes the properties of neural
stem cells in the developing brain of an infected fetus, potentially causing microcephaly in newborns (Ki - Jun Yoon, abstract 103.06, see attached summary).
«We've figured out for the first time how to produce these cells from
human embryonic
stem cells literally
by the billions and billions,» Lanza says.
Some of the researchers at the centre will study the differentiation of
stem cells into other cell types, one group
by using
human embryonic
stem cell biology and another
by studying early embryo development.
In a separate but related study, scientists this week also announced that they successfully reversed Parkinson - like symptoms in several monkeys
by transplanting
human neural
stem cells into their brains.
Published in Molecular Neurobiology, the study led
by Dr Elodie Siney under the supervision of Dr Sandrine Willaime - Morawek, Lecturer in
Stem Cells and Brain Repair at the University, analysed how enzymes called ADAMs affect the movement and function of the
human tumor cells.
The new rules state that
stem cells can be used if they are part of a study approved
by the federal government, or if the protocol has been approved
by an Institutional Review Board (IRB) that provides ethical review for research involving
human volunteers.
Varghese and her team showed that they could control the differentiation of
human pluripotent
stem cells into functional osteoblasts — bone - building cells — simply
by adding the molecule adenosine to their growth medium.
Scientists headed
by Dr. Stevens Rehen differentiated
human induced pluripotent
stem (iPS) cells into neural
stem cells and into further complex tridimensional structures, known as neurospheres and brain organoids.
By promoting DNA demethylation, high - dose vitamin C treatment induced
stem cells to mature, and also suppressed the growth of leukemia cancer
stem cells from
human patients implanted in mice.
Researchers at the University of California San Diego have discovered an easy and efficient way to coax
human pluripotent
stem cells to regenerate bone tissue —
by feeding them adenosine, a naturally occurring molecule in the body.
Human embryonic
stem cell (hESC) research had been backed
by federal funds for more than a decade, but a surprise August injunction
by a federal judge threw the field's future into question.
Then, a team led
by Robert Lanza, the chief scientific officer of Advanced Cell Technology Inc. in Marlborough, Massachusetts, and his colleagues published the first results ever of a clinical trial using
human embryonic
stem cells.
Human hematopoietic
stem and progenitor cells (HSPCs), derived from bone marrow, have become a primary vehicle for efforts to replace or regenerate cells destroyed
by a variety of diseases.
To do this, they created a cellular model of Werner syndrome
by using a cutting - edge gene - editing technology to delete WRN gene in
human stem cells.
This event will provide an overview of the recent National Research Council report, «Successful K - 12
STEM Education,» as well as give examples of innovative research - based tools for engineering education funded
by the National Science Foundation's Directorate for Education and
Human Resources.
Suzuki and his group hope that
by further manipulating the chemical environment of the spheres of
stem cells, they may increase that number, further easing the path toward
human treatment.
They've figured out how to turn
human stem cells into functional pancreatic β cells — the same cells that are destroyed
by the body's own immune system in type 1 diabetes patients.
Now comes a first rate example of how CRISPR is changing the pace of biomedical research
by linking up with another cutting edge technology —
human pluripotent
stem cells (hPSCs).
The study was supported
by a Science of
Human Appearance Career Development Award from the Dermatology Foundation and
by grants from the Medical Research Council of the UK, the Empire State Development's Division of Science, Technology and Innovation (NYSTAR), New York
Stem Cell Science (NYSTEM), and the Biotechnology and Biological Sciences Research Council in the UK (BBSRC), as well as earlier support from the Steven and Michele Kirsch Foundation.
The results obtained
by Afsaneh Gaillard's team and that Pierre Vanderhaeghen at the Institute of Interdisciplinary Research in
Human and Molecular Biology show, for the first time, using mice, that pluripotent
stem cells differentiated into cortical neurons make it possible to reestablish damaged adult cortical circuits, both neuroanatomically and functionally.
To see whether cancer
stem cell renewal involves a chain of events similar to that used
by embryonic
stem cells, and whether the process was affected
by oxygen levels, Semenza and graduate student Chuanzhao Zhang focused their studies on two
human breast cancer cell lines that responded to low oxygen
by ramping up production of the protein ALKBH5, which removes methyl groups from mRNAs.
The recipe, described in Nature, allows
human pluripotent
stem cells to spontaneously attempt to assemble into a tiny approximation of a whole brain
by making whatever brain structures the
stem cells choose.
The study, «VlincRNAs controlled
by retroviral elements are a hallmark of pluripotency and cancer» found that novel non-coding parts of the
human genome known as vlincRNAs (very long intergenic, non-coding RNAs) triggered
by ancient viruses, participate in the biology of
stem cells, and in the development of cancer.