Sentences with phrase «by hypersensitivity»

Atopy (canine atopic dermatitis) is caused by a hypersensitivity to aeroallergens such as pollens, house dust mites, or mold spores.

The researchers said some PMS symptoms might be caused by hypersensitivity to prolactin, a hormone produced by the pituitary gland that stimulates milk production.

Not exact matches

It is not hypersensitivity to feel threatened by the presence of the symbol.

The drug reduced the pain hypersensitivity induced by the nerve injury (or accompanying inflammation) but did not affect nociceptive pain — the protective pain sensation that helps us avoid injury.

To better determine the role of specific chemoattractants in type III hypersensitivity, lead author Yoshishige Miyabe, MD, PhD, a research fellow in Luster's lab, used multiphoton intravital microscopy — an imaging technology pioneered for studies of immune cell movements in living animals by CIID investigator and co-author Thorsten Mempel, MD, PhD — to follow in real time the development of IC - induced arthritis in a mouse model of rheumatoid arthritis.

Inflammatory arthritis includes a number of autoimmune diseases of the joints — including rheumatoid arthritis and lupus — and in many cases is caused by a type of inflammation called type III hypersensitivity.

«By engineering mice that have these mutations only in their peripheral sensory neurons, which detect light touch stimuli acting on the skin, we've shown that mutations there are both necessary and sufficient for creating mice with an abnormal hypersensitivity to touch.»

«For the first time, this research shows that the hypersensitivity experienced by chronic pain patients may result from hypersensitive brain networks,» says co-senior author Richard Harris, Ph.D., associate professor of anesthesiology at Michigan Medicine with the Chronic Pain and Fatigue Research Center.

«This hypersensitivity, however, is not always a gift: being captured by the myriad of sensory stimuli we continuously receive from the environment can be distracting and even overwhelming, and prevents us to focus on what we care most,» says Cerliani.

Up to 40,000 U.S. women may be affected by seminal plasma hypersensitivity, an immune reaction to male ejaculate.

A study by researchers at the University of Southampton and Southampton General Hospital, is the first to assess the prevalence of two different types of food hypersensitivity and the risk factors associated with them.

In fact, «it also opens the way to using drugs that block the NMDA receptor — another regulator of neuronal excitability leading to hypersensitivity in painful processes — and to avoiding the serious side effects resulting from their high toxicity — sedation, nausea, dissociative reactions, behaviour modification, etc. — nowadays induced by these drugs,» argues Hipólito.

Titled «Peripheral Hypersensitivity to Subthreshold Stimuli Persists after Resolution of Acute Experimental Disc - Herniation Neuropathy and Is Mediated by Heightened TRPV1 Receptor Expression and Activity,» the study promises to shed light on the basis of neuropathic pain that persists after apparently successful surgery.

Hypersensitivity is an exaggerated immune response by the body to an agent — but is not the same as a diagnosed allergy.

Other hypersensitivity reactions (II, III and IV) are mediated by other antibody classes, immune cells or cellular components.

Mechanical hypersensitivity, sympathetic sprouting and glial activation are attenuated by local injection of corticosteroid near the lumbar ganglion in a rat model of neuropathic pain.

Another measure of clinical relevance which has emerged recently is the increased hypersensitivity to pain stimuli caused by sleep restriction in rats.

June issue: Constructing a classification of hypersensitivity / allergic diseases for ICD - 11 by crowdsourcing the allergist community Tanno LK et al..

Susan Amara, USA - «Regulation of transporter function and trafficking by amphetamines, Structure - function relationships in excitatory amino acid transporters (EAATs), Modulation of dopamine transporters (DAT) by GPCRs, Genetics and functional analyses of human trace amine receptors» Tom I. Bonner, USA (Past Core Member)- Genomics, G protein coupled receptors Michel Bouvier, Canada - Molecular Pharmacology of G protein - Coupled Receptors; Molecular mechanisms controlling the selectivity and efficacy of GPCR signalling Thomas Burris, USA - Nuclear Receptor Pharmacology and Drug Discovery William A. Catterall, USA (Past Core Member)- The Molecular Basis of Electrical Excitability Steven Charlton, UK - Molecular Pharmacology and Drug Discovery Moses Chao, USA - Mechanisms of Neurotophin Receptor Signaling Mark Coles, UK - Cellular differentiation, human embryonic stem cells, stromal cells, haematopoietic stem cells, organogenesis, lymphoid microenvironments, develomental immunology Steven L. Colletti, USA Graham L Collingridge, UK Philippe Delerive, France - Metabolic Research (diabetes, obesity, non-alcoholic fatty liver, cardio - vascular diseases, nuclear hormone receptor, GPCRs, kinases) Sir Colin T. Dollery, UK (Founder and Past Core Member) Richard M. Eglen, UK Stephen M. Foord, UK David Gloriam, Denmark - GPCRs, databases, computational drug design, orphan recetpors Gillian Gray, UK Debbie Hay, New Zealand - G protein - coupled receptors, peptide receptors, CGRP, Amylin, Adrenomedullin, Migraine, Diabetes / obesity Allyn C. Howlett, USA Franz Hofmann, Germany - Voltage dependent calcium channels and the positive inotropic effect of beta adrenergic stimulation; cardiovascular function of cGMP protein kinase Yu Huang, Hong Kong - Endothelial and Metabolic Dysfunction, and Novel Biomarkers in Diabetes, Hypertension, Dyslipidemia and Estrogen Deficiency, Endothelium - derived Contracting Factors in the Regulation of Vascular Tone, Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension, Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs, Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants including Polypehnols and Ginsenosides Adriaan P. IJzerman, The Netherlands - G protein - coupled receptors; allosteric modulation; binding kinetics Michael F Jarvis, USA - Purines and Purinergic Receptors and Voltage-gated ion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) transporters

Our studies establish that the H19 and U2af1 - rs1 DMRs have a specialized organization of chromatin characterized by nuclease hypersensitivity at the unmethylated chromosome.

By allowing replisome rotation, absence of the Tof1 / Csm3 complex promotes the conversion of impending topological stress to DNA catenation and causes camptothecin hypersensitivity.

Through synthetic viability screening, we discovered that histone H4 K16 deacetylation drives the sensitivity of yeast cells to camptothecin and that inactivation of this pathway by mutating H4 K16 or the genes SIR1 - 4 suppresses much of the hypersensitivity of tof1 ∆ strains towards this agent.

Finally, some chronic cough can be explained by cough hypersensitivity syndrome.

These are known as food allergies; however, there is a much more common type of food hypersensitivity known as food intolerance.Different from food allergies, with the key issue being that food intolerance is not caused by the immune system.

These antibodies are mediated by the IgG branch of the immune system (different branch than the one that makes food allergies)- this is known as a Type IV Delayed Hypersensitivity reaction.

This step - by - step method shows you how to rewire chronic illness disease patterns in the brain that are associated with Multiple Chemical Sensitivities, Chronic Fatigue Syndrome, Fibromyalgia, Depression, Chronic Pain, Electric Hypersensitivity Syndrome, Anxiety, Food Sensitivities, Postural Orthostatic Tachycardia Syndrome, Lyme Disease, Irritable Bowel Syndrome, Mold Toxicity and more.

The Chronic Candida Syndrome (also, Candidiasis Hypersensitivity Syndrome [CHS], or Candida Related Complex [CRC]-RRB- is characterized by a collection of diverse symptoms, and there are several schools of thought about contributing factors.

Their food related problems might reflect an adverse additive effect of multiple modest hypersensitivity reactions mediated, for instance, by immune complexes promoting autoimmune reactions in the joints.»

These reactions are known as Type I Hypersensitivity Reactions and are governed by the IgE branch of the immune system.

In case you're experiencing an obscure sustenance hypersensitivity response, chamomile helps by its chamazulene content, a mitigating specialist.

Allergic and other hypersensitivity reactions to foods can actually characterized by elevated allergen - specific antibody levels in you blood, and you can get IgE tests from online companies like DirectLabs.

My main problems are subclinical hypothyroidism «probably caused by autoimmune inflammation of the thyroid gland» (my doctor says) and electromagnetic hypersensitivity (EHS), which is not an official diagnosis, but unfortunately a very real problem for me, and for an increasing amount of people.

The term erethism (or reddening), which derives from a person's tendency to blush, 3 covers a constellation of personality traits including timidity, diffidence, contentiousness, insecurity, bluntness, rigidity, excitability and hypersensitivity to criticism and to sensory stimulation.4 - 6 Considering mercury's subtle but reproducible effects on emotions, it is likely that a number of problems blamed on character, personality or stress may in fact be caused or compounded by low - level mercury toxicity.

There is evidence that interstitial nephritis results mainly from a delayed hypersensitivity response to NSAID, and nephrotic syndrome results from changes in glomerular permeability mediated by prostaglandins and other hormones.

Food sensitivities that are more subtle and delayed are mediated by a different immune complex, Immunoglobulin G (IgG), and are referred to as delayed hypersensitivity reaction allergies.

It is also possible that tetracycline treatment improves rheumatic illness by reducing delayed - type hypersensitivity response.

Oral allergy syndrome is a type I immediate hypersensitivity reaction mediated by IgE induced by sensitization to pollen.

Frequently caused by flea bites, or a hypersensitivity to an allergen.

Inherited form seen in Dachshunds; secondary form caused by friction, hormonal abnormalities, or hypersensitivities

Hypersensitivity to certain foods is commonly seen by veterinarians, with soy protein as a recognized allergen for dogs.

The most obvious symptom of flea bite hypersensitivity and FAD is severe itching of the skin, which your pet attempts to cope with by scratching and biting.

The triggers for Cardiff's IMHA are unclear, so I do my best to prevent him from suffering from another hemolytic episode by avoiding known immunostimulants (vaccination, hypersensitivity from insect invenomation, bacteria from ticks and fleas, etc.).

Brewer's dried yeast has been considered controversial by many dog owners because it has been associated with incidence of hypersensitivity reactions and allergies in dogs which are sensitive to yeast.

Certain vaccines have a higher likelihood of producing adverse reactions, especially reactions caused by Type I hypersensitivity.

The hypersensitivity response triggers the infiltration of the digestive tract by various inflammatory cells.

It is especially formulated for use in kennel cough as well as other forms of inflammatory and hypersensitivity processes deemed appropriate by your veterinarian.

Important in identifying systemic hypersensitivity, which can be caused by heartworm disease, flea bite dermatitis, feline asthma, allergic gastroenteritis and more

FAD also known as flea bite hypersensitivity is an allergic reaction to flea saliva injected by the bites of fleas.

The size of the skin reaction depends on the hypersensitivity of the dog to the flea bite antigen and the amount of antigen injected into the skin by the parasite.

The Merck Manual describes encephalitis as «an acute inflammatory disease of the brain due to direct viral invasion or to hypersensitivity initiated by a virus or other foreign protein.