Sentences with phrase «by immune destruction»

Researchers have found that some mothers of autistic children create antibodies to the brain tissue of their fetus, meaning the child is a born with a brain already developmentally imbalanced by immune destruction.

Not exact matches

Type 1 diabetes, formerly known as juvenile diabetes, is characterized by the immune system's destruction of the beta cells in the pancreas.

In particular, it has evolved to show itself three to nine months after infection, allowing its own destruction by displaying antigens on its cell surfaces so the dog's immune system can destroy it.

This is characterised by the targeted strengthening of the body's own immune cells, unlike in chemotherapy, in which the aim is direct destruction of the cancer cells.

Slusher teamed up with Johns Hopkins Kimmel Cancer Center immunologist Jonathan Powell, M.D., Ph.D., who has studied how cancer cells use different metabolic pathways to evade destruction by immune cells.

The key to this approach is minimizing healthy tissue damage while maximizing cancerous tumor destruction of the sort that improves recognition of the tumor by the immune system.

Multiple sclerosis is characterized by an abnormal immune response that leads to inflammation in the brain and the destruction of myelin — a fatty sheath that protects and insulates nerve fibers.

These proteins aid in marking bacteria invading the lung for destruction by the immune system.

The immune system does not normally attack «self» proteins, so by producing protein fragments, or peptides, that imitate the structure of those in the body's own tissues, viruses and bacteria may avoid destruction.

Yet despite its long residence in the body, the malaria parasite somehow avoids destruction by the immune system.

No one knows for certain how the parasite survives in its host for so long, evading destruction by the immune system.

By attaching to the myeloma cells, it marks them for destruction, and by attaching to NK cells, it primes the immune cells to search for and attack the myeloma celBy attaching to the myeloma cells, it marks them for destruction, and by attaching to NK cells, it primes the immune cells to search for and attack the myeloma celby attaching to NK cells, it primes the immune cells to search for and attack the myeloma cells

Thus, by the time they are macroscopic, these tumors are poorly immunogenic, and more resistant to immune - mediated destruction.

The selective pressure of the competent immune system «edits» the tumor by selecting for cells that can avoid immune destruction.

epitope - a specific part on the surface of a virus that is targeted for destruction by the body's immune system.

«The destruction of red blood cells outside of vessels by immune cells in PNH has long been speculative due to limited experimental evidence.»

This enhances the immune response through multiple mechanisms: by attaching to the myeloma cells, it marks them for destruction, and by attaching to the NK cells, it primes the immune cells to search for and attack the myeloma cells.

Researchers have discovered that a subset of human antibodies have catalytic activity against a particular antigen, breaking it down into smaller and less harmful fragments instead of trapping it for removal or destruction by other immune cells.

These «surface proteins» are easily recognized by the immune cells and targeted for destruction.

The high doses of therapy lead to the destruction of a patient's own marrow and immune system, which is then replaced by marrow from a donor or from peripheral blood stem cells that have been harvested before therapy.

Sophisticated cell targeting systems such as the gene therapy approach developed for senescent cell clearance by Oisin Biotechnologies could also be turned to stem cell or immune cell destruction, given suitable markers of cell chemistry.

The destruction and recreation of the immune system wins out because it is already possible, already demonstrated to be successful, and just missing one component part that would enable it to be used by ordinary, healthy, older people.

One of the main reasons cancer remains difficult to treat is that cancer cells have developed a multitude of mechanisms that allow them to evade destruction by the immune system.

Another potential mechanism through which iodine exacerbates or induces Hashimoto's is by up - regulating Th17 cells, the immune cell subset responsible for tissue destruction in autoimmune disease, and by suppressing development of regulatory T cells, the population that invokes oral tolerance to arrest autoimmune responses (31).

Trypsin inhibitors, prevent the ulcer - causing bacteria H. pylori from attaching to the walls of the stomach, prevent the destruction of immune factors by digestive enzymes.

Antibodies are proteins made by the immune system that attach to the affected tissue to tag it for destruction.

Though not a terribly artful filmmaker, Robertson is good with actors in close - up (even if it is overused) and at allowing his patiently agitating camera to show the grit of dead - end poverty that the brother's gang world represents and Gen needs to escape: a pit of self - destruction populated by bleary - eyed toughs eager to brutalize and immune to hope.

Addison's disease is primarily caused by an immune — mediated destruction of adrenal tissue.

The majority of cases are caused by immune - mediated destruction of the tear glands.

Although this may be due to such factors as trauma or infection, the main cause appears to be progressive destruction of the tear glands by the dogs own auto - immune system.

More recently, a topical medication called imiquimod has been used in both canine and human infections to help boost immune - mediated inflammation and thus facilitate destruction of the virus by the body.

IDDM can also be triggered by infectious virus diseases, immune deficiencies that result in destruction of the insulin - producing cells in the pancreas, pancreatic infections, steroids and reproductive hormones, and Cushing's disease.

Hypothyroidism is commonly caused by an auto - immune response; that is, the body creates antibodies directed against the thyroid glands causing their destruction.

This discoloration is the result of excessive bilirubin in the bloodstream, which can be the result of either backed up liver circulation due to disease, or as the result of excessive accumulation of bilirubin due to the destruction of red blood cells caused by a disruption in red blood cell metabolism, a defective immune system, or both.

The etiology of β - cell destruction in diabetic dogs is often unknown, although there is evidence that it is frequently caused by immune - mediated processes similar to human type 1 diabetes (70 — 72,82 — 84).

We will identify an ITP disease profile by measuring immune cells and proteins that may be involved platelet destruction.

Our project aims to investigate the specific causes of ITP by identifying an ITP disease profile by measuring immune cells and proteins that may be involved platelet destruction.

While in many cases we don't know the causes of an underactive thyroid gland and thyroid atrophy in dogs, in other cases there is an autoimmune destruction of the thyroid gland by the dog's own immune system.

ACT - activated clotting time (bleeding disorders) ACTH - adrenocorticotropic hormone (adrenal gland function) Ag - antigen test for proteins specific to a disease causing organism or virus Alb - albumin (liver, kidney and intestinal disorders) Alk - Phos, ALP alkaline phosphatase (liver and adrenal disorders) Allergy Testing intradermal or blood antibody test for allergen hypersensitivity ALT - alanine aminotransferase (liver disorder) Amyl - amylase enzyme — non specific (pancreatitis) ANA - antinuclear antibody (systemic lupus erythematosus) Anaplasmosis Anaplasma spp. (tick - borne rickettsial disease) APTT - activated partial thromboplastin time (blood clotting ability) AST - aspartate aminotransferase (muscle and liver disorders) Band band cell — type of white blood cell Baso basophil — type of white blood cell Bile Acids digestive acids produced in the liver and stored in the gall bladder (liver function) Bili bilirubin (bile pigment responsible for jaundice from liver disease or RBC destruction) BP - blood pressure measurement BUN - blood urea nitrogen (kidney and liver function) Bx biopsy C & S aerobic / anaerobic bacterial culture and antibiotic sensitivity test (infection, drug selection) Ca +2 calcium ion — unbound calcium (parathyroid gland function) CBC - complete blood count (all circulating cells) Chol cholesterol (liver, thyroid disorders) CK, CPK creatine [phospho] kinase (muscle disease, heart disease) Cl - chloride ion — unbound chloride (hydration, blood pH) CO2 - carbon dioxide (blood pH) Contrast Radiograph x-ray image using injected radiopaque contrast media Cortisol hormone produced by the adrenal glands (adrenal gland function) Coomb's anti- red blood cell antibody test (immune - mediated hemolytic anemia) Crea creatinine (kidney function) CRT - capillary refill time (blood pressure, tissue perfusion) DTM - dermatophyte test medium (ringworm — dermatophytosis) EEG - electroencephalogram (brain function, epilepsy) Ehrlichia Ehrlichia spp. (tick - borne rickettsial disease) EKG, ECG - electrok [c] ardiogram (electrical heart activity, heart arryhthmia) Eos eosinophil — type of white blood cell Fecal, flotation, direct intestinal parasite exam FeLV Feline Leukemia Virus test FIA Feline Infectious Anemia: aka Feline Hemotrophic Mycoplasma, Haemobartonella felis test FIV Feline Immunodeficiency Virus test Fluorescein Stain fluorescein stain uptake of cornea (corneal ulceration) fT4, fT4ed, freeT4ed thyroxine hormone unbound by protein measured by equilibrium dialysis (thyroid function) GGT gamma - glutamyltranferase (liver disorders) Glob globulin (liver, immune system) Glu blood or urine glucose (diabetes mellitus) Gran granulocytes — subgroup of white blood cells Hb, Hgb hemoglobin — iron rich protein bound to red blood cells that carries oxygen (anemia, red cell mass) HCO3 - bicarbonate ion (blood pH) HCT, PCV, MHCT hematocrit, packed - cell volume, microhematocrit (hemoconcentration, dehydration, anemia) K + potassium ion — unbound potassium (kidney disorders, adrenal gland disorders) Lipa lipase enzyme — non specific (pancreatitis) LYME Borrelia spp. (tick - borne rickettsial disease) Lymph lymphocyte — type of white blood cell MCHC mean corpuscular hemoglobin concentration (anemia, iron deficiency) MCV mean corpuscular volume — average red cell size (anemia, iron deficiency) Mg +2 magnesium ion — unbound magnesium (diabetes, parathyroid function, malnutrition) MHCT, HCT, PCV microhematocrit, hematocrit, packed - cell volume (hemoconcentration, dehydration, anemia) MIC minimum inhibitory concentration — part of the C&S that determines antimicrobial selection Mono monocyte — type of white blood cell MRI magnetic resonance imaging (advanced tissue imaging) Na + sodium ion — unbound sodium (dehydration, adrenal gland disease) nRBC nucleated red blood cell — immature red blood cell (bone marrow damage, lead toxicity) PCV, HCT, MHCT packed - cell volume, hematocrit, microhematocrit (hemoconcentration, dehydration, anemia) PE physical examination pH urine pH (urinary tract infection, urolithiasis) Phos phosphorus (kidney disorders, ketoacidosis, parathyroid function) PLI pancreatic lipase immunoreactivity (pancreatitis) PLT platelet — cells involved in clotting (bleeding disorders) PT prothrombin time (bleeding disorders) PTH parathyroid hormone, parathormone (parathyroid function) Radiograph x-ray image RBC red blood cell count (anemia) REL Rocky Mountain Spotted Fever / Ehrlichia / Lyme combination test Retic reticulocyte — immature red blood cell (regenerative vs. non-regenerative anemia) RMSF Rocky Mountain Spotted Fever SAP serum alkaline phosphatase (liver disorders) Schirmer Tear Test tear production test (keratoconjunctivitis sicca — dry eye,) Seg segmented neutrophil — type of white blood cell USG Urine specific gravity (urine concentration, kidney function) spec cPL specific canine pancreatic lipase (pancreatitis)-- replaces the PLI test spec fPL specific feline pancreatic lipase (pancreatitis)-- replaces the PLI test T4 thyroxine hormone — total (thyroid gland function) TLI trypsin - like immunoreactivity (exocrine pancreatic insufficiency) TP total protein (hydration, liver disorders) TPR temperature / pulse / respirations (physical exam vital signs) Trig triglycerides (fat metabolism, liver disorders) TSH thyroid stimulating hormone (thyroid gland function) UA urinalysis (kidney function, urinary tract infection, diabetes) Urine Cortisol - Crea Ratio urine cortisol - creatine ratio (screening test for adrenal gland disease) Urine Protein - Crea Ratio urine protein - creatinine ratio (kidney disorders) VWF VonWillebrands factor (bleeding disorder) WBC white blood cell count (infection, inflammation, bone marrow suppression)

Lymphocytic thyroiditis, probably immune - mediated, is characterized histologically by a diffuse infiltration of the gland by lymphocytes, plasma cells, and macrophages and results in progressive destruction of follicles and secondary fibrosis.

By modifying its Osp's, the spirochete is able to change its presentation to the mammalian host's immune system thus escaping immune destruction.

Point by point these articles by Dana Priest and William Arkin reveal what is to me a sad tale of madness, of a nation suffering from the political equivalent of some auto - immune disease where the response to invasion is unregulated growth and self destruction.