ANIMALS LESS THAN AGE SIX MONTHS Seizures are usually caused
by infections of the brain.
This inflammation can be caused
by infection of the brain (bacterial, viral, fungal and parasites are examples of infectious causes of encephalitis) or can be immune - mediated; which means the body's immune system is malfunctioning and creating abnormal inflammation for reasons we do not fully understand.
Not exact matches
However, one third
of cases are triggered
by damage to the
brain from causes such as head injury, stroke, tumours or
infection.
Johns Hopkins researchers report that fetal mice — especially males — show signs
of brain damage that lasts into their adulthood when they are exposed in the womb to a maternal immune system kicked into high gear
by a serious
infection or other malady.
As well as revealing step
by step how disease and
infection can aggravate and accelerate the early stages
of Alzheimer's, Perry and his colleague Clive Holmes have begun a pioneering trial in 40 people to see if a drug that acts to dampen inflammation in the body can help delay the progress
of the
brain disease.
THE
brain function
of infants may be boosted or hindered
by infections experienced
by their mothers during pregnancy.
Outside
of the
brain, cytokines are released
by immune cells fighting
infections, and they can alter MHCI expression in a complicated feedback loop.
The
brain is protected
by a barrier
of cells that tightly regulates the transport
of substances into this organ in order to prevent
infection.
An association between Zika
infections during pregnancy and the birth
of babies with microcephaly (a birth defect in which an infant's
brain does not develop properly resulting in a smaller than normal head) was first suggested
by Brazilian physicians in August 2015, and in November microcephaly cases potentially associated with Zika started to be recorded; three months later WHO made its announcement.
Although the scientists can't assume hospitalization is directly causing suicide, they say their work backs up a hot theory that inflammation — one
of the body's main defenses against
infection — influences depression
by generating a chemical that interferes with
brain signaling.
«A growing body
of evidence suggests that immune system activation, such as that caused
by bacterial and viral
infections, can play important roles in many
brain disorders,» explained William Carlezon, PhD, chief
of the Division
of Basic Neuroscience at McLean Hospital, and senior author
of the paper.
On the safety side, the panelists delved into the possible risks
of injecting genetically modified cells into patients, including the potential for deadly viral
infections,
brain toxicity, and, paradoxically, the growth
of new tumors brought about
by CAR - T cells years after treatment.
In this case, prenatal
brain development is initially normal, but then disrupted
by the viral
infection of neural progenitors.
«These findings provide new insight into the mechanisms and timing
of the
brain disruption caused
by Zika
infection, and the sequence
of developmental anomalies that may occur,» said del Campo, who also serves as a medical geneticist at Rady Children's Hospital - San Diego.
It has historically been considered to be caused
by factors such as birth asphyxia, stroke and
infections in the developing
brain of babies.
This
brain slice from a human autopsy has taken on vivid color in the hands
of a neuroscientist: green from
infection by a lentivirus, red for neurons, blue for the nuclei
of brain cells.
«We can see that the
brain is affected
by all types
of infections.
Moreover, it seems that the immune system itself can affect the
brain to such an extent that the person's cognitive ability measured
by an IQ test will also be impaired many years after the
infection has been cured,» explains MD and PhD Michael Eriksen Benrós, who is affiliated with the National Centre for Register - Based Research at Aarhus BSS and the Mental Health Centre Copenhagen, University
of Copenhagen.
Encephalitis caused
by the immune system attacking the
brain is similar in frequency to encephalitis from
infections, Mayo Clinic researchers report in Annals
of Neurology.
«Normally, the
brain is protected
by the so - called blood -
brain barrier (BBB), but in the case
of infections and inflammation, new research has shown that the
brain can be affected on account
of a more permeable BBB.»
According to Michael Eriksen Benrós, the increased risk
of mood disorders can be explained
by the fact that
infections affect the
brain:
I have an ongoing interest in sickness behaviour responses induced
by bacterial and viral
infections / mimetics and our observation
of an exaggeration
of these responses in animals / persons with ongoing
brain inflammation has brought 2
of my major interests together: Such responses in the aged or demented incorporate episodes
of delirium, a phenomenon that remains unexplained and which now represents a major research interest for me.
«We have been working for three years to develop a better research model
of brain development, and it's fortunate we can now use this one to shed light on the major public health crisis posed
by Zika
infections,» says Hongjun Song, Ph.D., professor
of neurology and neuroscience at the Johns Hopkins University School
of Medicine's Institute for Cell Engineering.
1) Rituximab was added to the induction as the majority
of PCNSL are CD20 + diffuse large B - cell lymphomas (DLBCL) and it was previously shown that the addition
of rituximab to CHOP chemotherapy has improved the prognosis in DLBCL outside the
brain.8 2) The intraventricular MTX / cytarabine treatment
of the Bonn protocol requiring an Ommaya reservoir was replaced
by intraspinal administration
of liposomal cytarabine in view
of the expected lower risk
of procedure - related
infections.
Many people with Alzheimer's die
of sepsis, which can be caused
by infections, and he believes
brain tissue samples could have been contaminated during autopsies with microbes from elsewhere in the body.
Brazilians show that the
infection by Zika virus kills glioblastoma, one
of the most common and aggressive kinds
of malignant
brain tumour in adults.
[D] Some attenuated Type I - infected animals have detectable parasite in
brain regions early during acute
infection, decreasing to undetectable levels (average
of uninfected indicated
by black dashed line).
The cause
of her readmission into hospital was meningitis —
infection of her nervous system,
brain and spinal cord,
by Ebola virus that remained from her initial
infection.
In addition, the mechanism
by which the ZIKV
infection can cause fetal
brain damage is not known, and some reports suggest that the virus is able to evade the normal immunoprotective responses
of the placenta.15 Zika virus is not the only pathogen associated with neonate microcephaly.
Gross
brain pathology from infants with presumed or laboratory - confirmed ZIKV
infection, primarily from neuroimaging, closely resembles neuropathology associated with congenital cytomegalovirus (CMV).48 The most notable difference is the distribution
of intracranial calcifications (ie, typically subcortical in congenital ZIKV
infection and periventricular in CMV).48, 49 Such calcifications are likely dystrophic and related to cell death, either
by necrosis, apoptosis, or both.50
Understanding Zika's mechanisms will illuminate how viral
infection leads to birth defects such as microcephaly, a condition marked
by an abnormally small head and
brain size, and could inform the development
of therapies and vaccines, the study authors said.
BETHESDA, MD —
Infection with Zika virus disrupts fetal
brain development
by interfering with the proliferation
of human neural progenitor cells (hNPCs), a type
of cell that drives neurodevelopment and proliferates into
brain and nervous system cells, according to research presented at the American Society
of Human Genetics (ASHG) 2016 Annual Meeting in Vancouver, B.C.
This
brain inflammation is caused
by the release
of cytokines, chemical messengers in the body that trigger an immune response, similar to a viral
infection.
If neurons are being starved
of glucose
by an
infection, they will be seeking energy substrates wherever they can find them, and
brain usage
of ketones will increase more rapidly than in starvation / fasting.
Grape seed extract has been shown to dramatically reduce the risk
of prostate cancer, fight
infection, improve sugar levels, increase cognitive ability
by slowing down the aging
of the
brain, boost «good» cholesterol (HDL) and strengthen blood vessels.
It appears that in response to
infection, the excess inflammatory cytokines produced
by the immune system decrease the output
of sleep inducing hormones to the sleep centers
of the
brain.
Allergy is simply your body's immune system going into overdrive because
of a present yeast
infection which leads to LGS (leaky gut syndrome), all
of this is caused
by an imbalanced gut, LGS is the cause for adrenal fatigue which causes
brain fog, fatigue, mood swings, irregular heart beats, weight gain and more.
Some theories suggest that fibromyalgia may result from stress - induced changes in the hippocampal area
of the
brain; others from stress - induced disruptions
of the hypothalamic - pituitary - adrenal (HPA) axis (which affects adrenal function and cortisol production); and still others from low levels
of the neurotransmitter, dopamine, caused
by genetic factors and triggered
by exposure to stressors, such as emotional distress, physical trauma, viral
infections or inflammatory disorders.
Now I find a lot
of people, they have a lot
of dysfunction like let's say you're having memory issues,
brain fog issues, mood issues — I find a lot
of issues today area emanating from the gut and feeding back into the
brain via inflammation, via dysbiotic bacteria, via
infections, via the
infection - like
by - product such as lipo — lipopolysaccharide, LPS, or endotoxin, via food allergens getting into your bloodstream, via pesticides and junk in the environment, getting into your gut and into your bloodstream and affecting your
brain.
I'd like for you to explain that to the hundreds
of thousands
of people out there with recurrent yeast
infections,
brain fog, and fatigue who have regained their lives
by taking anti - fungal / anti-microbial herbs and other therapies to kill off excess candida.
It appears that in response to
infection, the excess inflammatory cytokines produced
by the immune system disturb the sleep centers
of the
brain.
The condition is generally caused
by damage to the
brain, but the injury may be the result
of any number
of things such as trauma, oxygen deprivation,
infection, stroke, chemical imbalance in the body, or drug abuse.
Secondary epilepsy (also known as «Symptomatic epilepsy») is when the fits are being caused
by another
brain disorder such a
brain tumour, an inflammation or
infection of the
brain (encephalitis), a
brain malformation, a recent or previous stroke or head trauma.
Cerebellar ataxia occurs when the cerebellum
of the
brain becomes damaged, often
by a
brain tumor or some kind
of infection.
While canine seizures may be caused
by head trauma,
brain tumors, toxins,
infections, birth defects and many other identifiable causes, the vast majority
of seizures in young dogs (one to three years old) are idiopathic or genetic epilepsy.
ACT - activated clotting time (bleeding disorders) ACTH - adrenocorticotropic hormone (adrenal gland function) Ag - antigen test for proteins specific to a disease causing organism or virus Alb - albumin (liver, kidney and intestinal disorders) Alk - Phos, ALP alkaline phosphatase (liver and adrenal disorders) Allergy Testing intradermal or blood antibody test for allergen hypersensitivity ALT - alanine aminotransferase (liver disorder) Amyl - amylase enzyme — non specific (pancreatitis) ANA - antinuclear antibody (systemic lupus erythematosus) Anaplasmosis Anaplasma spp. (tick - borne rickettsial disease) APTT - activated partial thromboplastin time (blood clotting ability) AST - aspartate aminotransferase (muscle and liver disorders) Band band cell — type
of white blood cell Baso basophil — type
of white blood cell Bile Acids digestive acids produced in the liver and stored in the gall bladder (liver function) Bili bilirubin (bile pigment responsible for jaundice from liver disease or RBC destruction) BP - blood pressure measurement BUN - blood urea nitrogen (kidney and liver function) Bx biopsy C & S aerobic / anaerobic bacterial culture and antibiotic sensitivity test (
infection, drug selection) Ca +2 calcium ion — unbound calcium (parathyroid gland function) CBC - complete blood count (all circulating cells) Chol cholesterol (liver, thyroid disorders) CK, CPK creatine [phospho] kinase (muscle disease, heart disease) Cl - chloride ion — unbound chloride (hydration, blood pH) CO2 - carbon dioxide (blood pH) Contrast Radiograph x-ray image using injected radiopaque contrast media Cortisol hormone produced
by the adrenal glands (adrenal gland function) Coomb's anti- red blood cell antibody test (immune - mediated hemolytic anemia) Crea creatinine (kidney function) CRT - capillary refill time (blood pressure, tissue perfusion) DTM - dermatophyte test medium (ringworm — dermatophytosis) EEG - electroencephalogram (
brain function, epilepsy) Ehrlichia Ehrlichia spp. (tick - borne rickettsial disease) EKG, ECG - electrok [c] ardiogram (electrical heart activity, heart arryhthmia) Eos eosinophil — type
of white blood cell Fecal, flotation, direct intestinal parasite exam FeLV Feline Leukemia Virus test FIA Feline Infectious Anemia: aka Feline Hemotrophic Mycoplasma, Haemobartonella felis test FIV Feline Immunodeficiency Virus test Fluorescein Stain fluorescein stain uptake
of cornea (corneal ulceration) fT4, fT4ed, freeT4ed thyroxine hormone unbound
by protein measured
by equilibrium dialysis (thyroid function) GGT gamma - glutamyltranferase (liver disorders) Glob globulin (liver, immune system) Glu blood or urine glucose (diabetes mellitus) Gran granulocytes — subgroup
of white blood cells Hb, Hgb hemoglobin — iron rich protein bound to red blood cells that carries oxygen (anemia, red cell mass) HCO3 - bicarbonate ion (blood pH) HCT, PCV, MHCT hematocrit, packed - cell volume, microhematocrit (hemoconcentration, dehydration, anemia) K + potassium ion — unbound potassium (kidney disorders, adrenal gland disorders) Lipa lipase enzyme — non specific (pancreatitis) LYME Borrelia spp. (tick - borne rickettsial disease) Lymph lymphocyte — type
of white blood cell MCHC mean corpuscular hemoglobin concentration (anemia, iron deficiency) MCV mean corpuscular volume — average red cell size (anemia, iron deficiency) Mg +2 magnesium ion — unbound magnesium (diabetes, parathyroid function, malnutrition) MHCT, HCT, PCV microhematocrit, hematocrit, packed - cell volume (hemoconcentration, dehydration, anemia) MIC minimum inhibitory concentration — part
of the C&S that determines antimicrobial selection Mono monocyte — type
of white blood cell MRI magnetic resonance imaging (advanced tissue imaging) Na + sodium ion — unbound sodium (dehydration, adrenal gland disease) nRBC nucleated red blood cell — immature red blood cell (bone marrow damage, lead toxicity) PCV, HCT, MHCT packed - cell volume, hematocrit, microhematocrit (hemoconcentration, dehydration, anemia) PE physical examination pH urine pH (urinary tract
infection, urolithiasis) Phos phosphorus (kidney disorders, ketoacidosis, parathyroid function) PLI pancreatic lipase immunoreactivity (pancreatitis) PLT platelet — cells involved in clotting (bleeding disorders) PT prothrombin time (bleeding disorders) PTH parathyroid hormone, parathormone (parathyroid function) Radiograph x-ray image RBC red blood cell count (anemia) REL Rocky Mountain Spotted Fever / Ehrlichia / Lyme combination test Retic reticulocyte — immature red blood cell (regenerative vs. non-regenerative anemia) RMSF Rocky Mountain Spotted Fever SAP serum alkaline phosphatase (liver disorders) Schirmer Tear Test tear production test (keratoconjunctivitis sicca — dry eye,) Seg segmented neutrophil — type
of white blood cell USG Urine specific gravity (urine concentration, kidney function) spec cPL specific canine pancreatic lipase (pancreatitis)-- replaces the PLI test spec fPL specific feline pancreatic lipase (pancreatitis)-- replaces the PLI test T4 thyroxine hormone — total (thyroid gland function) TLI trypsin - like immunoreactivity (exocrine pancreatic insufficiency) TP total protein (hydration, liver disorders) TPR temperature / pulse / respirations (physical exam vital signs) Trig triglycerides (fat metabolism, liver disorders) TSH thyroid stimulating hormone (thyroid gland function) UA urinalysis (kidney function, urinary tract
infection, diabetes) Urine Cortisol - Crea Ratio urine cortisol - creatine ratio (screening test for adrenal gland disease) Urine Protein - Crea Ratio urine protein - creatinine ratio (kidney disorders) VWF VonWillebrands factor (bleeding disorder) WBC white blood cell count (
infection, inflammation, bone marrow suppression)
Progressive Multifocal Leukoencephalopath This is a white matter
of the
brain disease caused
by a virus
infection.
Typical conditions covered
by an individual critical illness insurance policy are: cancer, stroke, heart attack, Alzheimer's disease, aortic surgery, aplastic anemia, bacterial meningitis, benign
brain tumour, blindness, coma, coronary artery bypass surgery, deafness, heart valve replacement, kidney failure, loss
of independent existence, loss
of limbs, loss
of speech, major organ failure on waiting list, major organ transplant, motor neuron disease, multiple sclerosis, occupational HIV
infection, paralysis, Parkinson's disease, and severe burns.
Typical conditions covered
by Critical Illness are cancer, stroke, heart attack, Alzheimer's disease, aortic surgery, aplastic anemia, bacterial meningitis, benign
brain tumour, blindness, coma, coronary artery bypass surgery, deafness, heart valve replacement, kidney failure, loss
of independent existence, loss
of limbs, loss
of speech, major organ failure on waiting list, major organ transplant, motor neuron disease, multiple sclerosis, occupational HIV
infection, paralysis, Parkinson's disease, and severe burns.