Sentences with phrase «by inflammation at»

Or they can develop something called enthesitis, a type of pain caused by inflammation at the places where tendons, ligaments, and joint capsules attach to the bone.

Not exact matches

Just look at this list of benefits from a recent study done at the Yale - Griffin Prevention Research Center by David L. Katz, MD, and his colleagues: «Cocoa can protect nerves from injury and inflammation, protect the skin from oxidative damage from UV radiation... and have beneficial effects on satiety, cognitive function, and mood.»

In the end, Washington was felled by what modern doctors think was a case of epiglottitis, an acute bacterial inflammation of the little flap at the base of the tongue that covers the trachea.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

However, curcumin has been shown to reduce inflammation, per a study conducted by cancer researchers at the University of Texas in Houston; so much so that athletes use it to aid muscle and broken bone recovery.

The effects of antibiotics on toothache caused by inflammation or infection at the root of the tooth in adults

There is one cause that is most commonly at the crux of all of these symptoms, as well as rashes, diarrhea, constipation, and wild behavior: allergy to or intolerance of certain food proteins — most often from cow's milk, but also sometimes from wheat, soy, and an array of other foods consumed by breastfeeding mom, in formula, or otherwise in baby's diet.8 These can cause irritation and inflammation in the intestines that lead at times to reflux, and more often to signs of distress that mimic reflux.

Researchers led by Grace Aldrovandi, MD, chief of the Division of Infectious Diseases at Children's Hospital Los Angeles, studied 11 biomarkers associated with inflammation, bone loss and / or bone formation in about 450 individuals — assessed by sex and HIV status — to try to determine causes of this differential bone loss.

Now, a team at the Wyss Institute for Biologically Inspired Engineering at Harvard University co-led by Wyss Institute Founding Director Donald Ingber, M.D., Ph.D., and Wyss Core Faculty member James Collins, Ph.D., has leveraged the Institute's proprietary human - organs - on - chips technology to microengineer a model of human intestinal inflammation and bacterial overgrowth in a human - gut - on - a-chip.

The arthritis is accompanied or preceded by fever for at least two - weeks that is daily («quotidian») for at least 3 of those days, with one or more of the following symptoms: red rash (evanescent erythematous rash), enlarged liver, spleen or lymph nodes, and inflammation of the tissue lining (serositis) of the lungs, heart, or stomach.

A pilot study led by researchers at Joslin Diabetes Center has revealed that it is possible to use magnetic resonance imaging (MRI) to «see» the inflammation in the pancreas that leads to type 1 diabetes.

Ivan Rodriguez at the University of Geneva, Switzerland, and his colleagues have identified a type of smell receptor in mice that seems to respond to disease - related molecules produced by bacteria, viruses, or as the result of inflammation.

Ferumoxytol leaks out of blood vessels in areas of inflammation and is taken up by immune cells called macrophages, which congregate at sites of inflammation.

The team verified the laboratory results in actual patients by looking at the inflammation in the nerves of AIDP patients at very high magnification.

Exactly how asthma begins and progresses remain a mystery, but a team led by researchers at Brigham and Women's Hospital and the Broad Institute of MIT and Harvard has uncovered a fundamental molecular cue that the nervous system uses to communicate with the immune system, and may potentially trigger allergic lung inflammation leading to asthma.

Senior author Madhav Dhodapkar, M.D., the Arthur H. and Isabel Bunker Professor of Medicine and Immunobiology, and chief of Hematology, said the study, using tissue and blood samples from humans and mice, shows that chronic stimulation of the immune system by lipids made in the context of inflammation underlies the origins of at least a third of all myeloma cases.

«The chemicals produced by cooking meats at high temperatures induce oxidative stress, inflammation and insulin resistance in animal studies, and these pathways may also lead to an elevated risk of developing high blood pressure,» said Gang Liu, Ph.D., lead author of the study and a postdoctoral research fellow in the department of nutrition at the Harvard T.H. Chan School of Public Health in Boston.

Now a study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) confirms that inflammation — an immune response that develops when the body attempts to protect itself from harmful stimuli — plays a role in the onset of delirium.

An oral biologic medication has successfully treated chronic, precancerous inflammation in the intestine, according to results of an animal study authored by an MD / PhD student in the University at Buffalo School of Medicine and Biomedical Sciences.

These mechanisms may include altered systemic inflammation as a consequence of depression, or even the role of lifestyle behaviors such as physical activity or nutrition, which are typically worsened by depression, and which may place an individual at risk for psoriatic arthritis.

By chemically removing the gut microbiome in zebrafish in the lab and then repopulating the gut with two to three bacterial species, University of Oregon biologist Karen Guillemin has shown that certain microbes are especially skilled at suppressing the host immune system and preventing inflammation — a discovery she thinks may have implications for human health.

«After six weeks, we saw reversals in inflammation, both clinically and by looking at cellular and molecular measures of osteoclast formation and inflammatory cytokines.»

Early results show that the capsules have cured 32 people infected with drug - resistant Clostridium difficile, a dangerous microbe that installs itself in the gut and causes inflammation marked by diarrhea, cramping and pain.Thomas Louie, an infectious disease physician at the University of Calgary in Alberta, presented the data on October 3 at ID Week, a meeting of infectious disease specialists.

A new study conducted by researchers in the Charles E. Schmidt College of Medicine at Florida Atlantic University is helping to shed light on the important link between inflammation and cancer, and how pre-existing inflammation may aid in the metastatic process.

«Colitis is generally assessed by a pathologist, so they have to sit down, look at various areas under a microscope, [and] score how bad the inflammation and the morphological changes of the crypts are in the intestines,» says Kozlowski, adding, «I just wanted to speed up that process.»

«Recently, we became aware that some of the inflammation in CRS with nasal polyps is generated by the nasal lining itself, when a particular protein pump (P - glycoprotein) is overexpressed and leads to the hyper - secretion of inflammatory cytokines,» said senior author Benjamin S. Bleier, M.D., a sinus surgeon at Mass..

If he is correct, the inflammation generated by the intervention could be at fault.

Wanting to understand what happens under chronic inflammation conditions, a team of researchers led by Freddy Radtke at EPFL's Swiss Institute for Experimental Cancer Research (ISREC) studied stem cells in the corneas of mice.

Genomic sequencing experts at Johns Hopkins partnered with pharmacologists at Stony Brook University to reveal a striking mutational signature of upper urinary tract cancers caused by aristolochic acid, a plant compound contained in herbal remedies used for thousands of years to treat a variety of ailments such as arthritis, gout and inflammation.

Researchers at Washington State University in Spokane have identified a potential new approach to combating the joint pain, inflammation and tissue damage caused by rheumatoid arthritis.

Understanding which cytokines are best for monitoring inflammation and immunosuppression, and knowing which are secreted by different immune cell types at each stage of maturation and activation, will provide essential insights into disease treatment options.

«However, except alveolar inflammation and dental caries, the «individual G61» was not affected by any of these diseases — a female skeleton from the Neolithic graveyard of Stuttgart - Mühlhausen,» says Dr. Heike Scherf of the Senckenberg Center for Human Evolution and Paleoenvironment at the University of Tübingen.

It started with an abscess at the site of injection, followed by raging systemic inflammation.

«Alcoholic liver disease is a spectrum of conditions that range from hepatic steatosis, which is fat deposition in the liver and it is reversible with sobriety, to alcoholic hepatitis which is a more severe condition characterized by extensive and severe inflammation in the liver and often requires hospitalization,» explained Valentina Medici, associate professor of internal medicine at UC Davis Health System as well as corresponding author for the study.

A new study at the University of Oregon, led by postdoctoral fellow Annah Rolig, took aim at that question with experiments in zebrafish to dissect whether changes in the abundance of certain gut bacteria can cause intestinal inflammation.

Researchers at St. Joseph's Healthcare Hamilton and McMaster University have successfully tested an antibody that can improve the quality of life for individuals with asthma by relieving inflammation in the lungs.

By inhibiting p38 MAPK, it prevents both inflammation in the glial cells and disruption of the neuronal messages at the synapse.

New technology helped the researchers identify a type of E. coli bacteria found in people with Crohn's disease that can trigger inflammation associated with spondyloarthritis, according to the study led by principal investigator Dr. Randy Longman and scientists from the Jill Roberts Center for Inflammatory Bowel Disease at NewYork - Presbyterian and Weill Cornell Medicine and the Jill Roberts Institute for Research in Inflammatory Bowel Disease at Weill Cornell Medicine, microbiologists at Cornell University and rheumatologists at Hospital for Special Surgery.

These trends may be explained in part by the yo - yo effects that high glycemic - index carbohydrates have on blood glucose, which can stimulate fat production and inflammation, increase overall caloric intake and lower insulin sensitivity, says David Ludwig, director of the obesity program at Children's Hospital Boston.

The research study which was led by Dr. Bryan Yipp, assistant professor in the Department of Critical Care Medicine at the Cumming School of Medicine and Tier II Canada Research Chair in Pulmonary Immunology, Inflammation and Host Defence, was recently published in CELL Host & Microbe.

To date, no medication has been successful at preventing or mitigating the damage caused by lung inflammation.

Now, a multidisciplinary research team led by David Eckmann, MD, PhD, Horatio C. Wood Professor of Anesthesiology and Critical Care at the Perelman School of Medicine at the University of Pennsylvania and professor of Bioengineering in Penn's School of Engineering and Applied Science, has found that when delivered by a microscopic transporter called a nanocarrier, steroids can access the hard - to - reach lung endothelial cells that need it most and are successful at preventing inflammation in mice.

Building on that work, the current paper looked at a less lethal strain, the H1N1 «swine flu,» that does not infect neurons, but which, the researchers showed, still caused inflammation in the brain via inflammatory chemicals or cytokines released by immune cells involved in fighting the infection.

Patients with major depressive disorder (MDD) have increased brain levels of a marker of microglial activation, a sign of inflammation, according to a new study in Biological Psychiatry by researchers at the University of Manchester, United Kingdom.

An association between inflammation biomarkers in both blood plasma and cerebrospinal fluid (CSF) and markers of Alzheimer's disease (AD) associated pathology, has been found by researchers at the University of Colorado Anschutz Medical Campus working with the University of Wisconsin Alzheimer's Disease Research Center and the University of California San Francisco Memory and Aging Center.

Under normal conditions, MDSCs regulate immune responses and inflammation by suppressing or stopping them at the right moment.

A new study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) has found that lower levels of vitamin D in the blood increase the risk of clinical relapse in patients with Ulcerative Colitis (UC), an inflammatory bowel disease that causes long - lasting inflammation and ulcers in the colon.

Older adults over age 65 are at high risk for developing pneumonia, an inflammation of the lungs typically caused by infection.

«Earlier studies have shown that vitamin E can help regulate the aging body's immune system, but our present research is the first study to demonstrate that dietary vitamin E regulates neutrophil entry into the lungs in mice, and so dramatically reduces inflammation, and helps fight off infection by this common type of bacteria,» said first author Elsa N. Bou Ghanem, Ph.D., postdoctoral scholar in the department of molecular biology and microbiology at Tufts University School of Medicine (TUSM).

Researchers at University of California, San Diego School of Medicine and University College Dublin (UCD) have found that augmenting a naturally occurring molecule in the body can help protect against obesity - related diseases by reducing inflammation in the fat tissues.