Sentences with phrase «by killer t»

They found that destruction of the cancer was mediated by killer T cells residing in the tumor rather than newly infiltrating killer T cells.

«By treating glioblastoma cells with decitabine, we found that we can unmask targets on the tumor cell that can be recognized by killer T cells.

Not exact matches

As if you can hear the Un-Carrier CEO say «but there's more,» T - Mobile has also added another killer punch to its unlimited data plan by offering two lines for just $ 100 inclusive of taxes and fees.

The problem with Wenger is that he has not the killer instinct like coachs as ferguson or mourinho, they have this winning mentality who make them able to do anything in order to win, even cheating, wenger is just a tryer, he does not give it all in the fight.The team was obviously missing 2 centers backs and one strong DM, he did not address the problem, the striker issue was addressed only by luck, if Man U did not get falcao for any reason, there was no back up plan for any other striker, remember he was in Roma.I believe his age has something to do with that as he shows the stubborness of senile people.I don t see Arsenal as a force until he moves on somewhere else.the board too is responsible for not kwowing football and trusting him blindly even when he clearly fail his duties.

Marta Monteiro and colleagues at the University of Lisbon, Portugal, studied mice protected from the animal equivalent of multiple sclerosis by natural killer T - cells (NKT), a class of white blood cell which helps to control the immune system.

Chronic HIV infection results in exhaustion of the immune system, a phenomenon characterized by dysfunctional HIV - specific killer T cells.

Their paper, which appears in Nature Communications, describes how an immune cell recruited to the tumor induces the programmed suicide, or apoptosis, of the killer T cells harnessed by many immunotherapies.

The so - called STEP trial, sponsored by pharmaceutical giant Merck & Co. and the federally funded HIV Vaccine Trials Network (HVTN), was the first to test the idea of stimulating the immune system's killer T cells to hunt for the virus more aggressively, in this case using a weakened form of the cold virus to carry three genes from HIV.

Histone deacetylase (HDAC) inhibitors have shown promise in «flushing out» HIV from latently infected cells, potentially exposing the reservoirs available for elimination by cytotoxic T lymphocytes (CTL), also called killer T cells.

An international team of scientists, led by Monash Biomedicine Discovery Institute researcher Dr Di Yu, and Dr Axel Kallies from the Walter and Eliza Hall Institute, have discovered that killer T cells, a specialised type of white blood cells, can find these «hidden» infected cells in tissue and destroy them.

Using a combination of human or specially engineered mouse cells in vitro and in vivo animal models, study senior investigator Judy Lieberman, MD, PhD; study lead investigator Farokh Dotiwala, PhD, with a team lead by the Brazilian parasitologist Ricardo Gazzinelli, DSc, DVM, found that when an immune killer cell, such as a T - cell or natural killer (NK) cell, encounters a cell infected with any of three intracellular parasites (Trypanosoma cruzi, Toxoplasma gondii or Leishmania major), it releases three proteins that together kill both the parasite and the infected cell:

Researchers led by St. Jude Children's Research Hospital have identified a genetic variation associated with influenza severity and the supply of killer T cells that help patients fight the infection.

Severe combined immunodeficiency — X1 (SCID - X1) is an X-linked inherited disorder characterized by an early block in T and natural killer (NK) lymphocyte differentiation.

Led by Ludwig Lausanne investigator Alexandre Harari and George Coukos, director of the Ludwig Institute for Cancer Research, Lausanne, the study shows that ovarian tumors harbor highly reactive killer T cells — which kill infected and cancerous cells — and demonstrates how they can be identified and selectively grown for use in personalized, cell - based immunotherapies.

Scientists have known that LPA is secreted by many types of cancer cells, appears to promote the growth and spread of tumor cells, and that immune cells known as CD - 8 «killer» T cells have several receptors for LPA.

One of these T cell subsets is comprised of the CD1d - reactive invariant natural killer T cells, and over the years we have studied the development, homeostasis, activation and regulation of function of these cells, as well as their specificity and the pathways leading to the processing and presentation of antigens by CD1d.

killer T cells (CD8)- a group of T cells that is activated by helper T cells (CD4) and have the ability to destroy cells infected by foreign invaders (such as viruses).

A later study by CRI scientists confirmed that patients with higher frequencies of infiltrating killer T cells had improved survival [2].

New research from La Jolla Institute for Allergy and Immunology lays the groundwork to parse how the virus interacts with its host and causes disease by pinpointing CD8 + T cells, a subset of T cells more commonly known as cytotoxic or killer T cells, as important gatekeepers that control Zika infection or limit the severity of disease.

«By exposing a crystallized form of the molecular complex to a high - intensity X-ray beam at the Australian Synchrotron,» Le Nours says, «we were able to obtain a detailed 3 - D image of the molecular interplay between the invariant natural killer T cell receptor and AH10 - 7.»

Human leukocyte antigen - G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD4 + CD25highFOXP3 + regulatory T cells.

Coukos, who is currently leading an ovarian cancer clinical trial sponsored by CRI's Clinical Accelerator, sought to understand why PD - 1 / PD - L1 immunotherapies are often ineffective for these patients, even though ovarian tumors are often infiltrated by «killer» T cells that recognize tumor - specific neoantigens and express high levels of PD - 1.

This type of «killer» T cell responds to previously encountered cell - surface molecules — including the fragments of SIV proteins encoded by the genes in the CMV / SIV vaccine — and destroys SIV - infected cells.

The earliest came from a landmark study in 1998 by Haruo Ohtani, M.D., who demonstrated that the presence and location of CD8 + killer T cells within the tumor microenvironment (aka «tumor - infiltrating lymphocytes,» or TILs) correlated with better outcomes in colon cancer.

We found that naive T cells transferred into MHC negative or allogeneic environments often fail to survive because of rejection and / or competition by natural killer (NK) cells, rather than failure to recognize a particular MHC allele.

First, biological aging causes the limited pool of immunological killer T - cells to be slowly taken over by defective («anergic») subpopulations that are no longer able to carry out their specialized work, and suppress the effectiveness of the rest of the system.

At the University of Arizona, SENS Research Foundation is funding research to restore the production of new killer T - cells while making room for them by purging the defective cells from the system.

Killer T - cells first emerge as naïve cells that are out on the lookout for entirely new threats, but in order to do their job, they must assume a specialty, being trained by other immune cells to recognize, seek out, and eliminate a very particular threat.

At the University of Arizona, SENS Research Foundation is funding proof - of - concept research to restore the health of the immune system in aging mice, by simultaneously increasing the ability to produce new killer T - cells while making room for them by purging defective cells from the system.

CD8 + T - cells (or killer T - cells) are a kind of immune cell that specializes in destroying cells that have been hijacked by viruses or by cancer.

Most viruses can be «cleared» by the body's own defences, partly due to cells called «killer T - cells», which learn to recognise the intruder and eliminate it.

Forest bathing is proven to lower blood pressure and heart rate, reduce stress hormone production, boost the immune system by increasing killer T cell production, and promote feelings of wellbeing.

Growth or function of different types of immune cells, like macrophages, neutrophils, natural killer cells, T cells, and B cells is impaired by zinc deficiency.

But when cortisol remains in the body two or more days, it affects the body's immune system by reducing its T - cell count, impairing memory, and reducing Natural Killer (NK) cells that fight viruses and even some kinds of tumors.

BEST SONG IN A DOCUMENTARY An Inconvenient Sequel: Truth to Power — «Truth to Power» — Written by Ryan Tedder and T Bone Burnett — Performed by OneRepublic (Paramount / Actual Films, Participant Media) Chasing Coral — «Tell Me How Long» — Written by Dan Romer and Teddy Geiger — Performed by Kristen Bell (Netflix / Exposure Labs) Cries From Syria — «Prayers for This World» — Written by Diane Warren — Performed by Cher with The West Los Angeles Children's Choir (HBO / Afineevsky — Tolmor Production, Cinepost Barrandov, Levy Entertainment Group, Studio Malibu) Dina — «Best I Can» — Written by Michael Cera — Performed by Michael Cera featuring Sharon Van Etten (The Orchard / Cinereach, El Peligro, Killer Films) Served Like a Girl — «Dancing Through the Wreckage» — Written by Linda Perry, Neil Giraldo, and Pat Benatar — Performed by Pat Benatar (Entertainment Studios, Freestyle Digital Media) Step — «Jump» — Written by Raphael Saadiq, Taura Stinson, and Laura Karpman — Performed by Cynthia Erivo (Fox Searchlight / Impact Partners, Stick Figure Productions)

Along with the crew of Coen Brothers characters along the way (a one - eyed John Goodman, a blind Stephen Root, Michael Badalucco, and others), O Brother also features fantastic color - corrected cinematography by Roger Deakins, a killer soundtrack by T - Bone Burnett, and the wonderfully offbeat script from the Coens themselves.

History gets skewed, however, as Kyle arrives in an already - altered 1984 in which Miss Connor is a far - from - fragile machine killer who's been protected since childhood by a T - 800 she calls «Pops» (Ahnold).

The Jackbox Party Pack 3 features four totally original titles: Trivia Murder Party challenges up to eight contestants to test their knowledge while being held captive by a hilariously unstable serial killer; Guesspionage is a game of percentages that asks up to eight players to guess the public's answers to thought - provoking questions; Tee K.O. combines your artistic side with witty wordplay by turning drawings and slogans from up to eight players into hysterical T - shirts; and Fakin» It tasks up to six players with secret, ridiculous instructions, with the exception of one clueless player who must lie and cheat to avoid being discovered as «The Faker.»

We have some amazing games in this Party Pack that we've all fallen in good, clean love with: there's Trivia Murder Party, a trivia game hosted by a serial killer, Guesspionage, a polling game based on answers from the public, Tee K.O., where you battle your witty T - shirts and slogans, Fakin» It, where one of your friends is a dirty liar and you have to catch them and finally, Quiplash 2, the sequel to our big, hit game... Uh, I forget what it was called.