Microscope images show that in normal skin (left) the top layer, called the epidermis (purple in bottom images), is fused to the dermis
by laminin 332 (green, in top images) and other proteins.
Not exact matches
As expected, additional experiments
by Abe showed that the F1 - actin flow was dependent on L1 - CAM interactions with
laminin.
The new study
by the Inagaki lab showed that neurons will produce four times more traction force when placed on adhesive substrates coated with
laminin than those without
laminin, assuring the axons reach their final destination.
Their young patient had a severe form of the disease known as junctional EB, caused
by a mutation in a gene encoding part of the protein
laminin 332, which makes up a thin membrane just below the epidermis.
Rapid spreading and mature hemidesmosome formation in HaCaT Keratinocytes induced
by incubation with soluble
laminin - 5r.
All basement membranes are built from
laminin and collagen IV networks stabilized
by nidogen / perlecan bridges.