Sentences with phrase «by lentiviral»

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector.

These images show the development of cancer (dark purple) in the mouse lung, initiated by lentiviral vector.

The study, titled «Restoration of spermatogenesis by lentiviral gene transfer: Offspring from infertile mice,» was funded by the National Institutes of Health, the March of Dimes Birth Defects Foundation, the Wayne and Gladys Valley Foundation, and the H. N. and Frances C. Berger Foundation.

This is a derivative of the TZM - bl cell line, engineered by lentiviral transduction to stably express human FcγRIIIa on the surface.

This is a derivative of the TZM - bl cell line, engineered by lentiviral transduction to stably express human FcγRI on the surface.

This is a derivative of the TZM - bl cell line, engineered by lentiviral transduction to stably express human FcγRIIb on the surface.

Germline Transmission and Tissue - Specific Expression of Transgenes Delivered by Lentiviral Vectors

Not exact matches

Single - cell mouse embryos were infected in vitro with recombinant lentiviral vectors to generate transgenic mice carrying the green fluorescent protein (GFP) gene driven by a ubiquitously expressing promoter.

The treatment involves collected blood stem cells carrying the genetic anomaly of patients and corrected them in the laboratory by introducing a healthy WAS gene using a lentiviral vector developed and produced by Genethon.

The plasmids expressing hsa - mir -7-1 and hsa - mir -7-2 precursors in lentiviral pCDH - CMV - MCS - EF1 - copGFP vector (System Bioscience) were supplied by Yin - Yuan Mo (University of Mississippi Medical Center).

(The test was the perfect complement for one conducted earlier by the Zhang lab for GeCKO, a lentiviral CRISPR library enabling genome - scale, knockout screening).

OMC also aims at potentiating the existing Conditional Mutagenesis Facility by implementing novel approaches to attain tissue -, stage - and site - specific transgene expression in mouse mutant strains, mainly through lentiviral vector - mediated transduction of blastocysts.

Provasi E, Genovese P, Lombardo A, Magnani Z, Liu PQ, Reik A, Chu V, Paschon DE, Zhang L, Kuball J, Camisa B, Bondanza A, Casorati G, Ponzoni M, Ciceri F, Bordignon C, Greenberg PD, Holmes MC, Gregory PD, Naldini L, Bonini C. Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer.

Role of the endocytic pathway in the counteraction of BST - 2 by human lentiviral pathogens.

Functional KL2 genes were delivered to the mice using lentiviral vectors, based on a crippled version of HIV that was first developed by Verma and Salk Institute colleagues in 1996.

Review of «Safety and efficacy of a tCD25 pre-selective combination anti-HIV lentiviral vector in human hematopoietic stem and progenitor cells» from Stem Cells by Stuart P. Atkinson

Preintegration HIV - 1 inhibition by a combination lentiviral vector containing a chimeric TRIM5 alpha protein, a CCR5 shRNA, and a TAR decoy.

Suppression of clonal dominance in cultured human lymphoid cells by addition of the cHS4 insulator to a lentiviral vector.

The degree of phenotypic correction of murine ß — thalassemia intermedia following lentiviral - mediated transfer of a human γ — globin gene is influenced by chromosomal position effects and vector copy number.

HEK293T cells were transfected with the following retroviral or lentiviral constructs, with their packaging vectors indicated in the parentheses, using FuGENE 6 reagent (Promega): pMX - puro - STAT5A * (provided by T. Kitamura, University of Tokyo; pCMV - Gag - Pol and pCMV - VSV - G); pLenti - EF - FH - TAZ - S89A (psPAX2 and pVSV - G); PLKO - NS and shTAZ lentiviral construct (provided by C. Linardic, Duke University; pCMV - Rev, pCVM - VSVG; pMDL).

Prior to transplantation, we analyzed the in vitro production of specific growth factors by unmodified hNPCctx and by hNPCctx transduced with a lentiviral gene construct designed to constitutively express GDNF (hNPCctx - GDNF)[11], [44].

Adenoviral vectors can be produced by human embryonic kidney (HEK293) and human embryonic retinal (PER.C6) cell lines (31), both of which also can be used for lentiviral vector production.

Lentivirus was produced by cotransfecting replication incompetent lentiviral vector with psPAX2 (Addgene, 12260) and pLP / VSV - G (Invitrogen).

We also demonstrated that this observation was not caused incidentally by a particular vectoring system: using intraductal injection of a lentiviral vector (Bu et al., 2009) to introduce caErbb2 to ductal epithelia, we also observed accelerated tumorigenesis in the parous group relative to the virgin group (Figure 1 — figure supplement 2).