The histamines
released by mast cells open up your dog's capillaries and this is what causes redness and inflammation.
Tryptase, when secreted
by mast cells of the immune system in the lung, can induce many of the symptoms of an asthma attack.
Allergic reactions are
driven by mast cells and basophils — types of inflammatory cells found in tissues and the bloodstream, respectively, that function as part of our immune system.
We now know that the many symptoms associated with food allergies in dogs are directly related to the release of histamine and other pro-inflammatory
substances by the mast cells of the immune system.
The tumors release excess amounts of the biological chemicals heparin and histamine, which are normally
produced by mast cells.
In addition, supplements like quercitin, bromelin, vitamin c, rutin, and others can help to strengthen the immune system and help to minimize excessive histamine release
by mast cells.
The triggers of acute inflammation are released
by mast cells, sensitive cells which are scattered throughout ordinary connective tissues and which react to tissue damage or other disturbance.
Antihistamines act by reducing the release of histamine
by the mast cells and are often very effective in controlling allergy symptoms.