Not exact matches
Mechanistic studies showed that IFN increases antitumor immune responses
by enhancing antigen presentation to T cells
by dendritic cells present in the tumor microenvironment.
A new
study published in Proceedings of the National Academy of Sciences and led
by researchers from the University of Pennsylvania now offers the first
mechanistic explanation for why this is the case.
Walter says his lab has a research agreement with Calico to pursue «basic
mechanistic work» on ISRIB, but that the new
study was not funded
by Calico.
Since scientists first decoded a draft of the human genome more than 15 years ago, many questions have lingered, two of which have been addressed in a major new
study co-led
by a Princeton University computer scientist: Is it possible, despite the complexity of billions of bits of genetic information and their variations between people, to develop a
mechanistic model for how healthy bodies function?
Notophthalmus viridescens, an urodelian amphibian, represents an excellent model organism to
study regenerative processes, but
mechanistic insights into molecular processes driving regeneration have been hindered
by a paucity and poor annotation of coding nucleotide sequences.
Introduced in 1992
by Kim and Chung (1), spinal nerve L5 / L6 ligation (SNL) in rats has become well recognized and accepted as an animal model for
mechanistic studies of peripheral neuropathy and for screening of novel analgesics.
During her residency in Human Genetics at the University of Bonn she pursued her research interest both in immunology and human genetics
by investigating expression quantitative trait loci (eQTLs), which underpin innate immune responses, and provide
mechanistic insights to complement genome - wide association
studies.
Visit the Frontiers of Photobiology: Nobel Lecture
by Aziz Sancar (The Nobel Prize in Chemistry 2015 «for
mechanistic studies of DNA repair») Nobel Lecture
by Roger Y. Tsien (The Nobel Prize in Chemistry 2008 «for the discovery and development of the green fluorescent protein, GFP») Interviews with Johann Deisenhofer, Robert Huber, Hartmut Michel (The Nobel Prize in Chemistry 1988 «for the determination of the three - dimensional structure of a photosynthetic reaction centre»)
Specific
mechanistic studies include an interrogation of the adhesion dynamics controlled
by the tetraspanin CD151 and affiliated adhesion receptors (Integrins and IgG cell adhesion receptors).
From these cell based and clinical
studies, we have developed important
mechanistic ideas such as activation of protein kinase C, the role of vascular endothelial growth factor (VEGF) and selective insulin resistance as some of the basic mechanisms for the pathogenesis of diabetic microvascular and cardiovascular diseases which are now widely
studied by multiple laboratories.
Studies are in animal behavior from
mechanistic and evolutionary perspectives
by using fruit flies, bees, and other insects.
«Future
studies can provide
mechanistic understanding
by examining how specific compounds in coffee are involved in telomere maintenance.»
A recent scientific review
by Nicole Templeman and colleagues (the Journal of Endocrinology) states that, «Genetic profiling
studies could be used to understand the
mechanistic underpinnings of this variation [individual responses to macronutrients].