Sentences with phrase «by messenger proteins»

Not exact matches

Then, researchers then sought a way to increase SMA gene product levels, the messenger RNAs (mRNAs), and thus protein levels by silencing or removing the SMN lnc - RNA.

DNA is transcribed into messenger RNA (mRNA) that carries the code to ribosomes, the molecular machines that build proteins by reading the mRNA instructions.

Splicing in vitro of a messenger RNA (mRNA) precursor (pre-mRNA) is inhibited by a monoclonal antibody to the C proteins (anti-C) of the heterogeneous nuclear RNA (hnRNA)- ribonucleoprotein (hnRNP) particles.

Exosomes are small vesicles which are secreted by all cells and contain proteins and messenger RNAs and microRNAs.

They bond to proteins called PIWI and guide them to the messenger RNA produced by the jumping genes, which the PIWI protein then destroys.

MicroRNAs are short RNA molecules that typically bind to complementary sequences in messenger RNAs, thereby controlling the amounts of specific proteins produced by cells.

Antril is meant to block the action of interleukin - 1, a messenger protein or «cytokine» which triggers immune responses when the body is attacked by microorganisms.

First, it is a quality control mechanism used by cells to eliminate faulty messenger RNA (mRNA)-- molecules that are essential for transcribing genetic information into the construction of proteins critical for life.

RNA is the chemical messenger by which the information in genes is translated into protein.

Studies of embryonic stem cells revealed that NANOG protein levels can be lowered by a chemical process known as methylation, which involves putting a methyl group chemical tag on a protein's messenger RNA (mRNA) precursor.

The conventional view is that the main function of RNA is to convey instructions from DNA to the protein - making factories in cells — a task carried out by large molecules of «messenger» RNA.

This binding of microRNA to messenger RNA prevents the protein from being made, either by blocking the process directly or by triggering other proteins that cut the messenger RNA into smaller pieces.

But researchers recently discovered that short pieces of RNA called microRNAs can control the production of specific proteins by targeting their messenger...

The researchers found a protein that helps prevent human herpes virus 8 from replicating by detecting a specific modification on viral messenger RNA.

Through mapping proteins that can restrict viral infections, the researchers found a protein called YTHDF2 that can help regulate the human herpes virus 8 by detecting the m6A modification on viral messenger RNA.

Recently, scientists learned that microRNA genes can control this essential process by coding for a microRNA strip that binds to the messenger RNA, effectively turning off production of the protein.

At the Dana - Farber Cancer Institute and the Broad Institute, for instance, Todd Golub, a specialist in the genetics of cancer, had spent a decade learning how to identify malignant tumors by the pattern of protein - coding messenger RNAs expressed in their cells.

«We're talking about messenger RNA (mRNA), which is used by the cell to synthesize these proteins.»

PARTICLE acts in three different ways to prevent expression of the MAT2A gene: 1) by winding around the MAT2A gene to create a DNA: RNA triple helix structure locking down the MAT2A gene promoter, 2) by binding the messenger RNA product of the MAT2A gene and preventing it being used for MAT2A protein synthesis and 3) transferring MAT2A messenger RNA into intracellular vesicles that are subsequently ejected from the cell.

Interleukin - 33 (IL - 33), discovered in 2003 by Jean - Philippe Girard's team, is a protein in the family of interleukins, soluble messengers that enable communication between cells in the immune system and play a crucial role in tissue inflammation.

Biochemist Nirenberg of the National Institutes of Health gave a seminar describing a groundbreaking experiment in which he and a colleague had discovered how the cell interprets messenger RNA — by reading one triplet, or codon, of nucleotide bases at a time — to line up the amino acids that form proteins.

In some prokaryotes as well as in the organelles of some eukaryotes, splicing can be self - catalyzed by particular ribozymes with the help of magnesium ions, without the intervention of any protein machinery: the group II introns ribozymes are in fact able to self - regulate their own removal from the filament, thus promoting the maturation of messenger RNA.

Sancar and his team looked for bits of CRY1 and CRY2 messenger RNA — a chemical indicating that cells are making the protein specified by the gene — in the mice.

One gene set that stood out involved components of the spliceosome, the molecular complex that helps prepare messenger RNA (mRNA) transcripts for protein production by removing noncoding segments called introns.

During this crucial step, messenger RNA (mRNA), which is a RNA copy of a gene's recipe for a protein, is translated by the cell's ribosome into the sequence of amino acids that will make up a newly synthesized protein.

Stephen Warren of Emory University in Atlanta and colleagues suspected that the neurodegeneration is caused by messenger RNA (mRNA) that serves as the template for the protein.

Exosomes and other extracellular vesicles (EVs) are small membrane vesicles containing protein, messenger RNA, microRNA, DNA, and lipids, which are secreted by various cells and are stable in body fluids including blood, saliva, urine, cerebrospinal fluid, and breast milk.

The first to be tested was the gene for interleukin - 2, a messenger protein made by cells of the immune system.

MicroRNAs lower the levels of proteins such as BDNF by binding to messenger RNA, the molecular middleman that carries instructions from genes to the protein - making machinery of the cell, and tagging it for destruction.

Work by scientists in 1998 unexpectedly showed that double - stranded RNA molecules could suppress the translation of messenger RNA (mRNA) into protein.

MicroRNAs, or miRNAs, are short, single - stranded bits of RNA that regulate the messenger RNA expressed by genes to create a protein.

PTC's GEMS technology exploits the regulatory mechanisms found in the untranslated regions of messenger RNA for the identification of small - molecule drugs that can treat diseases by selectively increasing or decreasing the expression of key proteins by modulating post-transcriptional mechanisms.

Splicing the process by which introns are removed from the pre-mRNA molecules and remaining exons are joined together, forming the final messenger RNA (mRNA) that is translated into proteins.

Short pieces of RNA, called microRNAs, control protein production by causing the proteins» RNA templates (known as messenger RNA or mRNA) to be disabled by the cell, according to Whitehead Institute scientists.

This has been used to create reporters for second messengers by using protein (domains) that undergo a conformational change upon binding of e.g. Ins (1,4,5,) P3, calcium or cAMP.

Yang — whose essay described examples of alternative splicing, a process by which the same stretch of DNA and its complementary messenger RNA can be spliced together in different ways and thus be translated into different proteins — will receive a $ 1000 prize.

White adipose tissue messenger RNA levels and serum concentrations of inflammatory cytokines (tumor necrosis factor - α, interleukin - 6, and monocyte chemoattractant protein - 1) were reduced by C3G, as did macrophage infiltration in adipose tissue.