These amino acids can subsequently be used
by the microbiota in the colon, or transported from the lumen into the portal blood stream.
Comparisons between germ - free and conventional rats showed that transcriptional and serum metabolite differences were mediated
by the microbiota and were not the direct result of diet composition...»
This altered metabolites (chemicals produced
by the microbiota) including short chain fatty acids (see below for those many benefits).
Biotin can actually be synthesized
by the microbiota — the beneficial bacteria in the gut.
In the large intestine, they are broken down
by the microbiota and promote the growth of certain beneficial bacteria.
Rather, it passes into the large intestine where it is broken down
by the microbiota.
Metabolism of polyphenols
by microbiota involves the cleavage of glycosidic linkages.
The extent to which traditional dietary items may mitigate inflammation and oxidative stress may be controlled, at least to some degree,
by microbiota.
The maintenance of the intestinal lining
by the microbiota similarly prevents autoimmune disease.
«Furthermore, because each particular macronutrient has the potential to be metabolized
by microbiota into unique metabolic signals, the greater the variety in signals, the greater the variety of responses possible.»
The effects of consuming emulsifiers were eliminated in mice devoid of microbiota (germ - free mice), and transplanting microbiota from emulsifier - treated mice to germ - free mice was sufficient to transfer alterations in intestinal epithelial cells» homeostasis, suggesting a central role played
by the microbiota in tumor development.
However, to date, only a handful of metabolites principally produced
by microbiota — rather than the host organism itself — have been identified.
Not exact matches
Our gut
microbiotas are made up of trillions of microorganisms that play an essential role in our overall well - being
by supporting digestion, synthesizing nutrients and vitamins and protecting against diseases.
The PDF, Microbes Make the Cheese, A Report from the American Academy for Microbiology explains: Cheese is created
by orderly successions of microbial communities that produce compounds responsible for cheese flavor... Each piece of cheese contains as many as 10,000,000,000 or 10 billion microbes... The added starter cultures dominate the cheese
microbiota, establishing conditions that select for the next microorganisms that will be capable of thriving in the changing cheese matrix.
A recent research study conducted
by the Sahlgrenska Academy at University of Gothenburg in Gothenburg, Sweden, in collaboration with DuPont Nutrition & Health (DuPont), yielded breakthrough results demonstrating that probiotic intervention can alter and modify intestinal
microbiota in patients with colon cancer.
«After birth the gut mucosa is challenged
by a myriad of antigens, from viruses to commensal
microbiota and dietary antigens.
A small study of 60 randomly selected 7 - year - old children, 31 delivered
by cesarean and 29 delivered vaginally, assessed
microbiota composition
by determining fecal
microbiota profiles using culture - independent fluorescent in situ hybridization and compared the respective effects of delivery mode on gut
microbiota (12).
In addition to providing protection against infections that may promote atopic disease, breast - feeding also promotes the establishment of an intestinal
microbiota that may protect against atopic disease, possibly
by stimulating tolerogenic cytokines, such as TGF - β, or stimulating a Th1 response (47).
Secretory antibodies in breast milk promote long - term intestinal homeostasis
by regulating the gut
microbiota and host gene expression
New research led
by Dr Nathalie Juge at the Quadram Institute has identified some of the molecules used to ensure bacteria in the gut
microbiota maintain healthy populations, in the correct locations in the body.
The inflammation cluster research groups led
by Saleh Ibrahim of the University of Lübeck, and John Baines of the MPI and CAU, correlated the genomic variations of hundreds of mice that partially develop skin inflammatory diseases with skin
microbiota.
In a recent study published in the journal Nature Communications on 17 September, John Baines, Saleh Ibrahim and their colleagues of the Inflammation Research Excellence Cluster show that composition of skin
microbiota is controlled
by the host genome and that skin bacteria may have a greater influence on inflammatory diseases than previously thought.
The new
microbiota may trigger weight loss, says gastroenterologist Lee Kaplan of Massachusetts General Hospital,
by sending chemical signals that cause the human host to burn more calories, which helps use up the body's fat reserves.
A team led
by gastroenterologists Sieglinde Angelberger and Walter Reinisch (Medical University Vienna) and microbiologists David Berry and Alexander Loy (University of Vienna) explored how a treatment called «fecal
microbiota transplantation» can be used to support microbial recolonization of the gut of patients with chronic intestinal inflammation (ulcerative colitis).
As noted
by Dr. Vicki Ellingrod — the Chair of this session, «Current state - of - the - art research in both animal models as well as humans point to the link between the gut
microbiota and mood and anxiety models, as well as the potential for psychiatric medications to directly affect the gut microbiome.»
Researchers working on the Ribeirão Preto campus of the University of São Paulo (USP) in Brazil have discovered that a bacterium found in the
microbiota associated with leafcutter ant species Atta sexdens rubropilosa produces the so - called «trail pheromones,» i.e, the aromatic chemical compounds used
by the ants to lay a trail to their nest.
«Also
by studying how the gut
microbiota usually recover after cholera, we gain new ideas about how to manage severely disturbed microbial communities, ideas that can be used to protect against diseases that often follow such disturbance, such as infections that commonly follow antibiotic use.»
The study, led
by Professor Margaret Morris, the Head of Pharmacology at UNSW, examined the impact of yo - yo dieting on the gut
microbiota of rats.
Previous research led
by Schiestl presented the first evidence of a relationship between intestinal
microbiota and the onset of lymphoma, a cancer that originates in the immune system.
«And we have evidence that the composition of the gut
microbiota is controlled
by the genomes of the mice.
Previous work
by the Schloss lab and others had hinted that protection against C. difficile colonization was likely due to multiple species within the gut
microbiota.
Studies show that if you alter your diet dramatically, for instance
by changing the proportion of fibres, proteins or fats, you will see relatively quick changes in your
microbiota.
This is an exciting possibility that builds on evidence that gut
microbiota can regulate social behavior and is being investigated
by Huhman and Chassaing.
At this stage, the
microbiota is greatly influenced
by diet, for example whether you are breastfed or not.
Some of these phenotypes can be partially transmitted
by gut
microbiota.»
Ridaura et al. (1241214; see the Perspective
by Walker and Parkhill) obtained uncultured fecal
microbiota from twin pairs discordant for body mass and transplanted them into adult germ - free mice.
These findings reveal transmissible, rapid, and modifiable effects of diet -
by -
microbiota interactions.
Microbiota or microbiome structure, gene expression, and metabolism were assayed
by 16S ribosomal RNA profiling, whole - community shotgun sequencing, RNA - sequencing, and mass spectrometry.
In addition, cohousing coprophagic mice harboring transplanted
microbiota from discordant pairs provides an opportunity to determine which bacterial taxa invade the gut communities of cage mates, how invasion correlates with host phenotypes, and how invasion and microbial niche are affected
by human diets.
Moreover, obese - phenotype mice were invaded
by members of the Bacteroidales from the lean mice, but, happily, the lean animals resisted invasion
by the obese
microbiota.
«Can chemicals produced
by gut
microbiota affect children with autism?.»
Identifying
microbiota - derived metabolites and understanding their effects on specific host functions could open up new avenues of basic and clinical research to develop safe, targeted therapies involving molecules that,
by definition, constitute the natural chemical makeup of the host.
Although GMCSF is mostly known for its role in inflammation, Dr. Merad's laboratory discovered that GM - CSF is produced in the normal gut
by specialized cells called innate lymphocyte cells (ILCs) in response to
microbiota signals.
«Fecal
microbiota transplants improve cognitive impairment caused
by severe liver disease: Fecal microbiome transfer significantly reduced the number of hospitalizations compared to standard of care treatment.»
She explained that phages outnumber their bacterial prey
by a factor of 10 to 1, and that they have been proposed as the agents of change in recipients of faecal
microbiota transplantations used to treat resistant or recurring bowel disease.
The human GI tract is colonized
by billions of bacteria and other microorganisms, belonging to hundreds of species that are collectively termed «
microbiota.»
«Current methods of identifying and quantifying these metabolites are unable to distinguish whether the metabolites are produced
by the host or the
microbiota,» said Lee.
By injecting daily a low dose of a large spectrum antibiotic they were able to reverse the effects of high fat diet on the
microbiota composition.
The bamboo - eating giant panda actually harbors a carnivore - like gut
microbiota predominated
by bacteria such as Escherichia / Shigella and Streptococcus, according to new research published this week in mBio ®, the online open - access journal of the American Society for Microbiology.
A deep global analysis of the gut
microbiota composition was done
by phylogenetic microarray analysis using a Human Intestinal Tract Chip (HITChip), an analytical device designed specifically for studying gut bacteria.