Not exact matches
More amazingly, we now
know that beneath the crust of Enceladus is a global ocean of liquid saltwater and organic
molecules, all being heated
by hydrothermal vents on the seafloor.
It is now well
known that vast amounts of water and over 120
molecules, including complex organic
molecules, are found in interstellar space, having been created
by stars and nebulae (the Orion Nebula alone churns out huge amounts of water).
By abstraction, we can account for certain types of events, but we can
no more predict the particular event than a chemist can predict the location of a single
molecule in a gas - filled chamber.
Mutations are indeed not, so far as we
know, selected
by any overall purpose favoring evolution; but this is compatible with there being short - run and very naive purposes, desires, or feelings in the atoms and
molecules constituting the genes, as well as in every cell and every metazoan with a nervous system.
... The direct synthesis of... nucleotides from prebiotic precursors in reasonable yield and unaccompanied
by larger amounts of unrelated
molecules could not be achieved
by presently
known chemical reactions» (5).
That approach —
known as electrospray ionization — ionizes large
molecules by dissolving them in a solvent and using an intense electric field to pull tiny charged droplets of solution from the end of a needle.
A class of small
molecules found in grapes, red wine, olive oil, and other foods extends the life of yeast cells
by approximately 70 % and activates genes
known to extend life span in laboratory animals.
Next, the team tested chemicals they suspected would react with the smelly
molecules to produce larger
molecules that could
no longer be smelled, or a different shape that would be perceived differently
by the nose.
To address this, scientists at Stanford University in Palo Alto, California, led
by chemist Jianghong Rao, have taken advantage of a naturally produced TB protein
known as BlaC to create an efficient detection method that uses a simple fluorescent
molecule.
3BP, part of a class of compounds
known as small
molecule drugs, was first studied as an anti-cancer agent more than a decade ago at Johns Hopkins
by biochemists Young Hee Ko and Peter Pedersen, together with radiologist Jeff Geschwind.
The rays do this
by causing
molecules in the ring
known as amide groups to shuffle from opposite sides of the carbon bond to the same side, loosening hydrogen bonds in the process.
Ten years later, no one
knows what was in the cloud of gases released
by the combustion of all that jet fuel and building material but science has revealed what was in the dust — cement, steel, gypsum from drywall, building materials, cellulose from paper, synthetic
molecules from rugs, glass fibers and human hair from the long decades of the two towers» use, among other items.
Tritium, another harmful radionuclide, can not be safely removed
by any
known purification system because it is incorporated within water
molecules.
According to Zhang, the branching structure of the ligands protects the surface of the nanocrystals
by occupying more space than straight - chain
molecules, creating a mechanical barrier through an effect
known as steric hindrance.
Luckily, the same exact
molecule is more inexpensively created from natural gas
by a few obscure Chinese chemical companies and a well -
known German multinational corporation.
At a certain ratio of cerium atoms to
molecules, self - assembly produced a symmetrical complex 2 - D pattern described originally
by Kepler and
known today as the snub square tiling.
These agents are called disaccharide derivatives, and they mimic a class of natural
molecules known as rhamnolipids, which are produced and secreted
by the bacterium itself.
But the flowers that Gaskett studies, called tongue orchids, can produce a
molecule that precisely mimics the pheromone made
by the females of the species Lissopimpla excelsa, commonly
known as dupe wasps.
The activity of the latter protein is
known to be blocked
by a small
molecule called Nutlin - 3.
What industrial chemists did
know was that
by tinkering with a highly reactive
molecule called a phenol they were able to devise countless synthetic chemicals for use in new materials.
Because nitric oxide breaks down very quickly, as soon as the chemical is
no longer being produced, the oxygen
molecules are again trapped
by the mitochondria and are not available for the production of light.
The ER / PR receptors also have no
known direct connection to the signaling
molecules activated
by MC1R.
Vtesse is currently running a late - stage clinical trial of the drug, a large sugar
molecule known as a cyclodextrin, in which it is injected
by lumbar puncture into the spinal fluid of children with the disease (see «Why are people fighting over a promising treatment for a fatal childhood disease»).
When prion protein
molecules are sequestered
by their misfolded counterparts, they can
no longer work as a scaffold for all these molecular interactions, which impairs the mechanisms evoked
by the brain chemicals important for mood.
For example, their surface is covered
by glycoconjugates that are essential for their survival and infectivity, but little is
known of the processes that lead to the synthesis of such
molecules.
If we
know, for example, that a cancer cell can be killed
by deactivating a certain enzyme, researchers can build a detailed, 3 - D computer model of the enzyme to look for
molecules that can go in and disable it.
The tool,
known as DESI mass spectrometry imaging (or Desorption ElectroSpray Ionization mass spectrometry imaging), works
by turning
molecules into electrically charged versions of themselves, called ions, so that they can be identified
by their mass.
The sulphur - containing
molecule methyl mercaptan is naturally produced in significant quantities on Earth only
by microbes, including some that make their pungent presence
known in the human body.
The Fem RNA breaks down a corresponding
molecule made
by a gene
known as Masculinizer, which is found on the Z chromosome.
This sensitivity was reversed
by an antibody
known to neutralise the
molecule.
Prior to the current study, the scientists already
knew that Rumi modifies Notch
by adding glucose
molecules to the protein.
Snippets of RNA
known as short interfering RNA (siRNA) turn off specific genes inside living cells
by destroying the messenger RNA
molecules that carry DNA's instructions to the rest of the cell.
But the nature of these dimers has been hotly debated because it was not
known whether the two beta - amyloid
molecules that form the dimer were linked
by a chemical bond or not.
Gleevec incapacitates the enzyme
by docking into a pocket on the enzyme's surface that is usually reserved for a signaling
molecule known as ATP.
The science team, led
by chemist Brett McGuire at the National Radio Astronomy Observatory (NRAO) in Charlottesville, Virginia, detected this
molecule's telltale radio signature coming from a nearby star - forming nebula
known as the Taurus Molecular Cloud 1 (TCM - 1), which is about 430 light - years from Earth.
When the scientists blocked Treg cells from accumulating in the fat
by targeting a
molecule that the immune cells require, mice
no longer developed type 4 diabetes in old age.
A proposed pathway to construct quantum computers may be the outcome of research
by a University of Oklahoma physics team that has created a new
molecule based on the interaction between a highly - excited type of atom
known as a Rydberg atom and a ground - state atom.
To explore the health consequences of quorum sensing in the crypts, the researchers introduced into the flow a
molecule that acts as an antagonist to turn off quorum sensing in chambers colonized
by the well -
known scourge of hospitals, methicillin - resistant S. aureus, or MRSA.
The researchers began
by creating large membrane models with embedded and dyed channel proteins; they then put them on a glass surface and measured them using a single -
molecule measuring method
known as fluorescence correlation spectroscopy.
Researchers at UT Southwestern Medical Center have found a new way that internal body clocks are regulated
by a type of
molecule known as long non-coding RNA.
The scientists did this
by manipulating a small
molecule known as sphingosine -1-phosphate (S1P), which they report is found in elevated levels in people with sickle cell disease.
Makoto Fujita and his team from Japan's University of Tokyo created scaffolding - like crystalline structures
known as metal - organic frameworks, or MOFs, whose empty spaces can soak up
molecules and provide an ordered array that enables the
molecules to then be characterized
by X-ray analysis.
Led
by reproductive biologist Alex Travis, the engineering effort focuses on a chain of enzymes that metabolize glucose
molecules into the biological fuel ATP (a process
known as glycolysis), which enables sperm locomotion.
In past work studying strains of E. coli
known to cause difficult - to - treat UTIs, the researchers showed that a
molecule called yersiniabactin that is secreted
by the bacteria sequesters copper, preventing it from accumulating to antibacterial levels.
«This experiment would be the first to look for life
by targeting the
molecules specific to life as we
know it,» says Christopher Carr, the lead engineer on the project.
«To reach their target, growing axons rely on
molecules known as guidance cues, which instruct them on which direction to take
by repelling or attracting them to their destination,» explains Dr. Charron, Director of the Molecular Biology of Neural Development research unit at the IRCM.
The findings suggest that the
molecule —
known as an antisense oligonucleotide — potentially could treat neurodegenerative diseases characterized
by abnormal tau, including Alzheimer's.
They found that these skin - resident immune cells function as «first responders» to skin injuries in part
by producing the
molecule known as interleukin - 17A (IL - 17A), which wards off infection and promotes wound healing.
«We may not even
know what we should be looking for in these asteroids, but
by looking at what
molecules we find, we can ask different and more questions about how they could have helped get life started.»
Selective imaging
by correlated optical and electron microscopy of protein
molecules of
known ages will clarify fundamental processes of protein trafficking in situ.