Sentences with phrase «by mutations within»

The two minor mutant haplotypes have not been seen in any other breed suggesting that these have arisen by mutations within the breed.

Cancer is caused by mutations within cells, which cause those cells to grow and multiply at unnatural rates.

Not exact matches

Using Atlantic killifish (Fundulus heteroclitus), the researchers examined whether mitochondrial - nuclear interactions alter the frequency of alternative forms of a gene that arise by mutation, called alleles, for over 11,000 nuclear DNA sequence variations within a population of the fish with mixed ancestry.

McCallion's strategy to make sense of all this data looks at the active genes in cells affected by a disease, groups of genes that interact with one another, their vulnerability to mutation and information from past scientific studies to filter more than a thousand gene candidates for disease risk down to just a handful within any one implicated region.

The team of scientists, comprising researchers from SISSA and Philadelphia's Temple University, began their research from an established fact: within the three - dimensional structure of protein, certain amino acids interact so closely with each other that the mutation of one of them must be counteracted by compensatory mutations of the others to keep the protein functional.

Within the multitude of oceanic bacteria alone, he calculated, any given gene is struck by four mutations every 20 minutes.

«This study is exciting because it shows that changes within the body can affect the progression of a disorder caused by a genetic mutation,» said Jim I. Koenig, Ph.D., program director at NINDS.

The team could establish the number of white blood cell - generating stem cells by studying the pattern of mutations found within the blood cells.

«Our study illustrates that self - guided mutation is relevant to life within Earth's subsurface and uncovers mechanisms by which viruses and archaea can adapt in this hostile environment,» said David Valentine, a professor in UCSB's Department of Earth Science and at the campus's Marine Science Institute (MSI).

«This study gives a glimpse into the mechanism by which different mutations within the same gene can cause distinct defects in the brain, and may help to explain how they may contribute to different disorders,» says Guoping Feng, the James W. and Patricia Poitras Professor of Neuroscience at MIT, a member of MIT's McGovern Institute for Brain Research, a member of the Stanley Center for Psychiatric Research at the Broad Institute, and the senior author of the study.

Most mutations are caused by chemical or radiation damage from the immediate environment or within the cell itself.

(D) Detection of selection defined by a hidden Markov model that identifies long genomic tracks with a high probability (≥ 0.80) of carrying advantageous mutations cosegregating within the six modern breeds.

Within this crucial region, two specific mutations, made by molecular biologist Qing Ye, rendered the receptors completely unresponsive to alcohol or anesthetics, presumably by changing the way the proteins folded.

Hereditary: Hereditary cancer is caused by abnormal, or mutated, genes that are passed down through generations within a family, causing family members who inherit the mutation to be diagnosed with certain types of cancers.

By the late stages of the disease, the brain is visibly shrunken and the ventricles - fluid filled spaces within the brain - are very enlarged compared to the brains of people without the mutation.

Breast cancer risk was higher if mutations were located outside vs within the regions bounded by positions c.2282 - c. 4071 in BRCA1 (HR, 1.46; 95 % CI, 1.11 - 1.93; P =.007) and c.2831 - c. 6401 in BRCA2 (HR, 1.93; 95 % CI, 1.36 - 2.74; P <.001).

Despite the nearly all - female cast, girl power is in short supply, as the actresses aren't given much complexity to work with, their whisper - thin characters eventually killed one by one by the unnatural forces within Area X, where genetic mutation takes place at hyperspeed.

By doing this the mutation can be reduced to extremely low levels within a relatively short time while the carriers» genes for desirable traits can be passed along.

Inspired by the growth and mutation of Brooklyn - based artist Cody Hoyt's ceramic works, «Fossil Record» explores how these new pieces have evolved within a traceable framework over the last few years.