Sentences with phrase «by nuclear reprogramming»
The ultimate goal of our laboratory is to generate ES - like cells directly from somatic cells by nuclear reprogramming... which converts adult cells back into embryonic state.
http://www.faith.org.uk/ Not exact matches
Subsequent procedures included mammalian somatic cell nuclear transfer, cell fusion, induction of pluripotency by ectopic gene expression, and direct reprogramming.
But the favored reprogramming technique, somatic cell nuclear transfer (SCNT), otherwise known as research cloning, is fraught with ethical pitfalls as well as technical difficulties because it entails creating a human embryo by inserting an adult cell nucleus into an ooctye.
«Nuclear Reprogramming in Cells,» by J.B. Gurdon and D.A. Melton, Science, Dec. 19, 2008.
The Cas9 / gRNA - modified fibroblasts were subjected to nuclear reprogramming by somatic cell nuclear transfer, resulting in live - born goats carrying single - gene mutation.
Somatic cells can be reprogrammed either by nuclear transfer into oocytes or by fusion with embryonic stem (ES) cells.
A brief history of stem cell research serves as an introduction, followed by coverage of stem cell fundamentals; chapters then explore embryonic and fetal amniotic stem cells, adult stem cells, nuclear reprogramming, and cancer stem cells.
Reprogramming by nuclear transfer might provide an important source of pluripotent stem cells from human beings, including patients needing cell therapies.