Sentences with phrase «by oligodendrocyte»

Cerebral white matter injury (WMI) persistently disrupts myelin regeneration by oligodendrocyte progenitor cells (OPCs).

Researchers at Osaka University found that B immune cells reside in the brains of developing mice, and play a key role in the myelination of neurons by oligodendrocytes.

Dr. Lyons and his team used zebrafish to study the formation of myelin sheaths by oligodendrocytes because this laboratory animal is transparent at early stages of its development, which allows investigators to directly observe cells within the organism.

It is formed by oligodendrocytes in the central nervous system and Schwann cells in the peripheral nervous system.

Not exact matches

Changes in motor neurons are involved in disease onset, but disease progression seems to be dictated by changes to astrocytes, microglia and oligodendrocytes.

Oligodendrocytes, the cells that are known to produce the myelin sheaths which enable saltatory conduction of action potentials along the myelinated axons, are modulators of signal transmission along neuronal connections (axons) and also promote neuronal survival by providing metabolic support.

Oligodendrocytes that were not exposed to interferon gamma were unaffected by guanabenz, suggesting that it enhances only an active stress response pathway.

Brain tumors arise in the glia, or supportive cells, of the brain and now are classified by their histology — characteristics visible via microscopy — and their cell of origin, either astrocytes or oligodendrocytes.

RIPK1, the researchers found, inflicts damage by directly attacking the body's myelin production plants — nerve cells known as oligodendrocytes, which secrete the soft substance, rich in fat and protein that wraps around axons to support their function and shield them from damage.

In vertebrates, the axons of many neurons are sheathed in myelin, which is formed by either of two types of glial cells: Schwann cells ensheathing peripheral neurons and oligodendrocytes insulating those of the central nervous system.

MS is a debilitating neurological disease caused by the destruction of oligodendrocytes, cells that build the myelin sheaths that surround the signal transmitting axons of neurons.

Oligodendrocytes, a type of brain cell that plays a crucial role in diseases such as multiple sclerosis, are more diverse than have previously been thought, according to a new study led by Sten Linnarsson, Karolinska Institutet / SciLifeLab and Gonçalo Castelo - Branco, Karolinska Institutet.

Regulation of L - type Ca + + currents and process morphology in white matter oligodendrocyte precursor cells by golli - myelin proteins.

Modulation of Canonical Transient Receptor Potential Channel 1 in the Proliferation of Oligodendrocyte Precursor Cells by the Golli Products of the Myelin Basic Protein Gene.

Regulation of store - operated and voltage - operated Ca2 + channels in the proliferation and death of oligodendrocyte precursor cells by golli proteins.

In the November issue of Nature Methods, a team led by Paul Tesar, PhD, a NYSCF — Robertson Investigator at Case Western Reserve University, published a novel method in producing oligodendrocyte cells, the cells that are damaged in myelin - related disorders such as multiple sclerosis.

Galactocerebrosidase - deficient oligodendrocytes maintain stable central myelin by exogenous replacement of the missing enzyme in mice.

Unfortunately, myelin can be easily damaged by a variety of pathological conditions, and stresses to the brain, and oligodendrocyte vulnerability to such damage is enhanced in the aged brain and in degenerative diseases.

Oligodendrocyte differentiation was induced by culturing the cells in DMEM / F12, 1 % N2, and IGF - 1 (200 ng / ml).

ab16667 staining Ki67 (red) in transgenic mouse spinal cord tissue sections (depleted of oligodendrocytes) by Immunohistochemistry (PFA perfusion fixed frozen sections).

We show that Olig2 + oligodendrocyte precursor - like glioma cells invade by single - cell vessel co-option and preserve the blood - brain barrier (BBB).

Evolution of the mammalian brain, in part, has been enabled by a class of glial cells, oligodendrocytes, which provide the myelin.

The NG2 chondroitin sulfate proteoglycan is a membrane - spanning protein expressed by several types of immature progenitor cells, including oligodendrocyte progenitors, chondroblasts, skeletal muscle myoblasts, smooth muscle cells, and pericytes.

Myelin is generated by specialized cells, oligodendrocytes in the brain and spinal column (the central nervous system, or CNS), and Schwann cells in the network of nerves outside the CNS that connect it with the rest of the body (the peripheral nervous system).

Nerve associated healing cells (astrocytes, oligodendrocytes, and Schwann cells) are stimulated by laser application possibly through the release of growth factors and other proteins necessary for healing.