You can send it to us via our Facebook page or through the contact form... Continue reading Research Roundup: 50,000 lives saved
by organ transplants, transgenic sheep aid in Huntington's disease, smell relates to weight gain in mice, and more!
Small example: the death of one person in an accident (bad) can result in saving the life of
another by organ transplant (good).
The immune response «is the same as that triggered
by organ transplant between individuals,» Xu says.
Not exact matches
As far as magic — I think many things we experience today would have been considered magic
by those of the past — flying through the air in an airplane,
transplanting organs from dying patients to living ones, sending pictures through the air, even just being able to capture and use electircity, etc., etc..
The situation is only made worse
by the increased trafficking in human beings, new forms of slavery, and trafficking in human
organs for the sake of
transplants.
At that time the technology of
transplant surgery was beginning to make progress, and some people suspected that the desire to establish in law a concept of brain death was motivated only
by the wish to obtain
organs for
transplant before those
organs had deteriorated (as they will rapidly when heart and lung activity fail).
Book Review: Raising the Dead:
Organ Transplants, Ethics, and Society,
by Ronald Munson (Oxford University Press).
An
organ donation campaigner and
transplant recipient has paid tribute to a teenage girl who broke a UK record
by saving eight lives through
organ donation.
Then in 1961 Stanley Jacob, a University of Oregon Health Sciences Center surgeon looking for a way to supercool animal
organs for
transplant experiments, learned of DMSO from Robert Herschler, a chemist employed
by the Crown Zellerbach paper company.
Lauren's Law was originally signed
by Governor Cuomo in October 2012, and was named for Lauren Shields, a Rockland County resident who received a life - saving heart
transplant at age 9 and became an advocate for
organ donation.
But our ability to help people who need
transplants is limited
by the number of
organ donors that come forward.
The campaign will take place at Auto Bureau's across the county, where specialists trained
by Upstate New York
Transplant Services or Unyts will be on hand to help people understand how to become an
organ donor.
The herpes virus typically does not cause major health problems until the immune system is compromised — after an
organ transplant,
by AIDS or another disease that affects the immune system, or in older age.
Transplanted organs rarely get a hero's welcome in their new home — in fact, they are often attacked viciously
by the host's immune system.
By examining information from the United Network for
Organ Sharing registry, the researchers identified 12,837 patients ages 18 to 59 years who received first - time liver
transplants between 2009 and 2013.
By 2009, Atala announced that his lab had
transplanted phalluses onto adult rabbits, which successfully used the manufactured
organs to breed.
Slight changes to the system for allocating deceased - donor kidneys could result in higher rates of
organ procurement and lead to more kidney
transplants across the country, according to new research co-authored
by an Indiana University Kelley School of Business professor.
Most cells from a foreign donor, such as in
transplanted organs, are targeted
by the immune system, but «this one has found a way to suppress the immune system of its hosts long enough to let it be passed along,» he says.
The immune system recognizes
transplanted organs as foreign tissue
by telltale proteins, called the major histocompatibility complex (MHC), that coat cell surfaces.
Because previous work in rats and monkeys has found that proteins that block the costimulatory signal can hold T cells at bay, Kim Olthoff, a
transplant surgeon at the University of Pennsylvania Medical Center in Philadelphia, thought her team could achieve a targeted immune suppression
by getting the
transplanted organ itself — rather than proteins injected into the bloodstream — to block the costimulatory signal.
Long - term preservation methods could help establish
organ and tissue banks, which would also reduce
transplant rejection rates
by facilitating the process to find matching donors when needed.
Their work has been avidly followed
by biologists in the field of
organ transplantation: If a donor's heart or kidney could be frozen and stored without damage, physicians could dramatically increase the number of
transplants they perform.
These boosters stimulate the regular production of antibodies — caused
by foreign substances in the body — toxins, bacteria, foreign blood cells, and the cells of
transplanted organs.
A healthy immune system will fight off anything it recognises as foreign, such as a microorganism or a
transplanted organ, unless it is suppressed
by potent drugs.
In the wake of the case, Pierre Kormann, administrative director of France -
Transplant, the organisation which coordinates
transplants, says that the number of refusals for donation of all
organs has increased
by 30 per cent.
Aside from dietary issues, the CMAH gene also proves to be a major factor in whether or not a
transplanted organ from an animal would be accepted
by a human because of the gene.
«Efforts to increase
organ donor consent rates
by all parties should be a major focus of the
transplant community and the general public,» Goldberg said.
Recently, medical researchers have discovered ways to treat neurological diseases, anaemia, leukaemia, epilepsy, stroke and several other conditions
by transplanting fetal tissue into brains and other
organs.
Findings of a three - year clinical trial led
by University of Cincinnati (UC)
transplant researchers suggest that a novel pre-operative drug therapy reduces antibodies in kidney patients with greater success than with traditional methods, with the potential to increase the patients» candidacy for kidney transplantation and decrease the likelihood of
organ rejection.
A new perspective paper written
by researchers at the Perelman School of Medicine at the University of Pennsylvania and published in The New England Journal of Medicine suggests that «new antiviral therapies with cure rates exceeding 95 percent should prompt
transplant - community leaders to view HCV (hepatitis C virus)- positive
organs as a valuable opportunity for
transplant candidates with or without pre-existing HCV infection.»
«We used mice with conditions that mimic those often found in
transplant patients — hyperlipidemia is common in patients before transplantation but can also be caused
by drugs to prevent
organ rejection — and discovered that it accelerates
organ rejection.
Some scientists suspect that immune cells activated
by the foreign
organ but lacking the CD154 signal die soon after a
transplant, although it's not clear why new generations of immune cells wouldn't recognize and attack the tissue.
The new dispute has flared just before a summit on
organ trafficking and
transplant tourism, to be held in Vatican City, Italy on February 7 and 8,
by The Pontifical Academy of Sciences.
The test monitors fragments of DNA released
by the
organ into the blood, when cells from the
transplant tissue are naturally broken down.
February 20, 2006 University of Chicago lung
transplant program approved The University of Chicago's new lung
transplant program has been approved
by the United Network for
Organ Sharing (UNOS) and will begin placing patients on the lung
transplant waiting list this week.
San Diego's first
organ transplant, a kidney
transplant, is performed on a 32 - year - old former aircraft worker with a kidney donated
by his older brother.
Regardless of the targeted
organ for cell replacement or regeneration, the shared challenges in cell therapies for diabetes such as
transplant procedure and immune rejection will be well - served
by the collective expertise within CCTD.
Lastly, the placenta secretes immune response regulators to give the fetus immune protection against the mother (so that the fetus is not rejected
by the mother's immune system, as a tissue graft or
organ transplant would be)(Rossant and Cross, 2001; Gilbert, 2003).
In theory, a
transplanted organ could hack into its host's nervous system
by growing axons that connect with the host's cells.
Mycophenolate mofetil is approved
by the U.S. Food and Drug Administration (FDA) to prevent
organ rejection in people who have received a kidney, heart, or liver
transplant.
Often used to prevent patients» bodies from rejecting
transplanted organs, rapamycin works
by increasing the numbers of regulatory T cells and block other aggressive types of T cells.
It is approved
by the U.S. Food and Drug Administration (FDA) for use in
transplant patients to reduce the chance of
organ rejection.
Cells can be removed from a patient and used to create new
organs for
transplant that will not be rejected
by the patient's body.
Focusing on kidney
transplants (
by far the most common type of
organ transplant performed), Saltzman and Pober are looking to apply the delivery system to a process known as ex vivo normothermic machine perfusion.
Using nanoparticles, Yale researchers have developed a drug - delivery system that could reduce
organ transplant complications
by hiding the donated tissue from the recipient's immune system....
Advances in immunosuppression have decreased the incidence of acute rejection, but the survival of all
organ transplants continues to be limited
by chronic rejection.
Researchers showed that certain biomarkers released
by the donor
organs might be used to detect
transplant injury earlier than current techniques.
By typing for HL - A antigens, donors and recipients of white blood cells, platelets, and
organs can be «matched» insuring good performance and survival of transfused and
transplanted cells.
More recently, Minnesota scientists have made headlines worldwide
by transplanting stem cells from umbilical cords and also
by using stem cells to engineer new animal
organs.
Sponsored
by the Rhode Island Hospital
Transplant Center and Rhode Island
Organ Donor Awareness Coalition (RIODAC), this...