Sentences with phrase «by oxidative stress by»

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By providing us with such a great array of antioxidant nutrients, cauliflower helps lower our cancer risk by helping us avoid chronic and unwanted oxidative stresBy providing us with such a great array of antioxidant nutrients, cauliflower helps lower our cancer risk by helping us avoid chronic and unwanted oxidative stresby helping us avoid chronic and unwanted oxidative stress.

Animal studies suggest that pumpkin seeds may help improve insulin regulation and help prevent diabetic complications by decreasing oxidative stress.4

Results of the study showed that the total antioxidant capacity in the bloodstream of the participants increased, and that their level of oxidative stress (as measured by the amount of carboxymethyllysine in their blood serum) decreased.

Antioxidants like polyphenols that may help reduce damage caused by free radicals and oxidative stress; and

Purple sweet potato color attenuates oxidative stress and inflammatory response induced by d - galactose in mouse liver.

The researchers added: «Other bioactive compounds present in nuts, including micronutrients, fibre, and phytochemicals, may also contribute to their cardio - protective effect by reducing inflammation, improving vascular reactivity as well as fasting glucose and insulin sensitivity, and by lowering oxidative stress status.

Because the toxicity is associated with oxidative stress and inflammation, the study explored antioxidant and anti-inflammatory effect of virgin coconut oil (VCO) supplementation in nephrotoxicity induced by MTX in rats.

The researchers experimented with inducing oxidative stress in a human cell line culture with and without VCOP (virgin coconut oil polyphenols) to observe how VCOP positively promoted catalase, a very important enzyme in protecting the cell from oxidative damage, and glutathione (GSH), a self - recycling antioxidant produced by the liver.

Although much less research exists on monk fruit and its components, preliminary studies show promise for improving insulin signaling by protecting the pancreatic insulin - releasing cells from oxidative stress (3, 4).

The in - vivo (animal) study «Enhanced memory in Wistar rats by virgin coconut oil is associated with increased antioxidative, cholinergic activities and reduced oxidative stress» was published in January of 2017.

The rats fed VCO had significantly less oxidative stress markers in their kidneys than the 5HPO fed rats, leading the researchers to conclude ``... virgin coconut oil has a potential to reduce the development of hypertension and renal injury induced by dietary heated oil, possibly via its antioxidant protective effects on the kidneys.»

By controlling inflammation and upregulating antioxidant systems in the body, we can help keep our mitochondria healthy by protecting their DNA from oxidative stress (6By controlling inflammation and upregulating antioxidant systems in the body, we can help keep our mitochondria healthy by protecting their DNA from oxidative stress (6by protecting their DNA from oxidative stress (6).

This exceptional food offers antioxidant and anti-inflammatory protection to your cells, preventing DNA damage caused by free radicals and reduces oxidative stress which leads to premature aging.

The second phase of the study reports results from 53 healthy, non-obese men and women between ages 21 and 50 who cut calories by 15 % over 2 years and underwent additional measurements for metabolism and oxidative stress.

The UMD and UMB team, led by research associate Eunkyoung Kim, used a discovery - driven approach based on the assumptions that chemical biomarkers relating to oxidative stress could be found in blood, and that they could be measured by common electrochemical instruments.

Oxidative stress is damage to the body caused by an accumulation of unstable molecules called free radicals.

While pursuing her project on how environmental contaminants and oxidative stress cause lung cancer, Gelhaus complemented her postdoctoral training by spending some time with other PIs at Penn. «She has worked hard to develop skills that are independent of those available in my own laboratory while working on a project that is central to my research program,» Blair writes in an e-mail to Science Careers.

«The chemicals produced by cooking meats at high temperatures induce oxidative stress, inflammation and insulin resistance in animal studies, and these pathways may also lead to an elevated risk of developing high blood pressure,» said Gang Liu, Ph.D., lead author of the study and a postdoctoral research fellow in the department of nutrition at the Harvard T.H. Chan School of Public Health in Boston.

Acetaminophen can cross the placental barrier, Ritz noted, and it is plausible that acetaminophen may interrupt fetal brain development by interfering with maternal hormones or through neurotoxicity, such as the induction of oxidative stress, which can cause the death of neurons.

«Lots of these major tradeoffs or shifts that we are seeing between traits are underlied by oxidative stress or antioxidant capacity — some kind balancing act,» Stahlschmidt says.

The blood analysis revealed that the human mothers exposed to higher levels of BPA and their infants showed signs of oxidative stress caused by overexposure to nitric oxide - derived free radicals.

In several studies, vitamin C administration attenuated the increases in oxidative stress markers caused by exercise.

In a series of cell - based studies, they showed that it both blocked a family of iron - containing, oxygen - sensing enzymes called hypoxia - inducible factor prolyl - hydroxylases (HIF - PHD) and, critically, protected neurons by activating genes that protect them from oxidative stress.

«These exciting new results suggest that drugs that reduce the activity of TRIM21 could be highly effective new tools for the treatment of conditions that are driven by high oxidative stress, including liver and heart disease,» Zong said.

Oxidative states are generally considered to be indicative of cellular stress; however, cells inherently release harmful reactive oxygen species during energy production, neutralized by intracellular antioxidative buffering systems.

Although ethylene (or ethene) is best known as a plant hormone, humans also produce it as consequence of oxidative stress, caused for example by the UV radiation from the sun.

Oxidative stress reflects an imbalance between the reactive oxygen that is generated by normal cell metabolism and the cell's ability to handle toxic byproducts from that metabolism.

These include lipid lowering; protection from oxidative stress and inflammation; modification of growth factors that can promote cancer; inhibition of nutrient sensing pathways by amino acid restriction and gut microbiota - mediated production of metabolites.

They can provide a range of beneficial effects, such as lowering inflammatory cytokines (chemicals released by the immune system that can cause problems in rheumatoid arthritis patients), reducing joint stiffness and pain, as well as lowering oxidative stress — the ability of the body to counteract or detoxify harmful chemicals.

«Oxidative stress caused by exposure to air pollutants may therefore play a role in the development of insulin resistance.

The imbalance created by oxidative stress produces peroxides and free radicals, which contribute to a number of degenerative conditions, including aging.

While nicotine decreases appetite by affecting the brain and some hormone levels, it results also in increased oxidative stress.

The increase in MMP - 13 activity could be triggered by oxidative stress, which is also a hallmark of diabetic peripheral neuropathy.

Therefore, the primary novelty of the discoveries reported here is that programming by prenatal chronic hypoxia of cardiac and vascular dysfunction in adulthood follows the induction of oxidative stress in the fetal heart and vasculature, and that cardiac and endothelial dysfunction in adulthood can both be prevented by maternal treatment with antioxidants during pregnancy.

Effects of oxidative stress induced by high dosage of dietary iron ingested on intestinal damage and caecal microbiota in Chinese Yellow broilers — Z. Y. Gou — Journal of Animal Physiology and Animal Nutrition

Oxidative Stress Protection by Exogenous Delivery of rhHsp70 Chaperone to the Retinal Pigment Epithelium (RPE), a Possible Therapeutic Strategy Against RPE Degeneration.

Abrogation of the cell death response to oxidative stress by the c - Abl tyrosine kinase inhibitor STI571.

Impaired transcriptional activity of Nrf2 in age - related myocardial oxidative stress is reversible by moderate exercise training.

Mitochondrial calcium and its regulation in neurodegeneration induced by oxidative stress.

Transcriptional repressor Rex is involved in regulation of oxidative stress response and biofilm formation by Streptococcus mutans.

In Ames dwarrf, Snell Dwarf mice, Klotho mice, GHKO mice who have little IGF and GH; and live longer than wild - type; we see that indeed insulin and glucose / nutrient / energy pathways (which create oxidative stress through excessive nutrient via elevated glycation blood glucose creating high glycated albumin and hemoglobin), that aging is acted on by IGF through hormones, GFs, GHs, acting on insulin signals, which act on survival genes (DAF / SIRT / FOXO).

On the one hand, it regulates progression from premalignancy to malignancy, most likely by preventing oxidative stress - induced death of HCC - initiating cells, thereby allowing such cells to accumulate multiple oncogenic mutations, while promoting their growth through mTORC1.

Significantly, cellular pathologies including impaired cellular trafficking and an increase in oxidative stress, were reduced by treatment with the identified compound.

Increased TBARS and ROS are markers for oxidative stress caused by increased generation of free radicals.

4 - The Redox is at the heart of it all, as lipid peroxidation load drops redox balance is greatly affected, meaning a cell redox state of little oxidative stress and inflammatory gene activation (by absence of lipid peroxidation after lipid remodeling).

The selective destruction of acinar cells by high dose of L - arginine may be partly attributed to disruption of protein metabolism, increased oxidative stress, and endoplasmic reticulum stress [6].

«Mitochondrial dysfunction, oxidative stress and apoptosis revealed by proteomic and transcriptomic analyses of the striata in two mouse models of Parkinson's disease.

Oxidative stress in fibroblasts induces the autophagic destruction of mitochondria, by mitophagy.

Oxidative stress is generated by reactive oxygen species (ROS) produced in response to metabolic activity and environmental factors.

In the absence of cellular oxidative stress, Nrf2 levels in the cytoplasm are maintained at low basal levels by binding to Keap1 and Cullin 3, which leads to the degradation of Nrf2 by ubiquitination [2], [5]--[9].