«Delaying diagnosis had a significant impact on the treatment eventually received
by patients in our study,» said lead author Dr Raviteja Miriyala, senior resident, Department of Radiotherapy and Oncology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Medications used
by patients in the study were: methylphenidate (Ritalin), dexmethylphenidate (Focalin), dextroamphetamine (Dexedrine), atomoxetine (Strattera) and lisdexamfetamine (Vyvanse).
Not exact matches
A new
study published
in the New England Journal of Medicine finds that Valeant Pharmaceuticals» infamous price hikes for a pair of heart drugs called nitroprusside and isoproterenol — whose prices were increased
by 310 % and 720 %, respectively — had significant downstream effects on
patient care.
The first step
in the process is to surgically remove the
patient's tumor and ensure that the
patient is cancer free
by confirming that there is no sign of cancer on blood tests and imaging
studies.
Other
studies, meanwhile, are examining tryp's potential efficacy as an antifungal agent; and as a prognostic indicator
in patients with brain cancer (as seen
by increased uptake of the amino acid on a PET scan).
Final
patient visits will be followed
by completing data entry for the more than 35,000
patient years of
study in REDUCE - IT, and typical database quality control measures, known as cleaning.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth
in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures
in European countries that may increase the amount of discount required on Gilead's products; an increase
in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift
in payer mix to more highly discounted payer segments and geographic regions and decreases
in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations
in ADAP purchases driven
by federal and state grant cycles which may not mirror
patient demand and may cause fluctuations
in Gilead's earnings; market share and price erosion caused
by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured
patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials
in its currently anticipated timeframes; the levels of inventory held
by wholesalers and retailers which may cause fluctuations
in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates
in the timelines currently anticipated; Gilead's ability to receive regulatory approvals
in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and
patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical
studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta
in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes
in its stock price, corporate or other market conditions; fluctuations
in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time
in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
For example, Eli Lilly & Co. (NYSE: LLY) has a phase 3
study of solanezumab under way
in mild to moderate Alzheimer's disease
patients that may slow disease progression
by breaking up amyloid plaque buildups thought to be a major cause of the disease.
In a
study, conducted
by a faith - based group no less, it was shown that ICU
patients who knew they were being prayed for tended to suffer more complications and problems than those who were not or did not know.
The abandoning ethic of assisted suicide is demonstrated
by studies showing depression
in many
patients requesting hastened death.
«A 1999 follow - up
by William S Harris et al. attempted to replicate Byrd's findings under stricter experimental conditions, noting that the original research was not completely blinded and was limited to only «prayer - receptive» individuals (57 of the 450
patients invited to participate
in the
study refused to give consent «for personal reasons or religious convictions»).
A
study of the
patients visited regularly
by the students (compared with a matched control group of other
patients) showed that the program had made a significant difference
in the general improvement and discharge rate of those visited.
They did it right, a nice
study in the hospital of heart attack
patients, those who were and were not prayed for, those who knew they were prayed for, those who did not, those prayed for
by family, those who didn't know, and they had strangers pray for them.
One such
study by the University of Utah found that healthy
patients who consumed unprocessed cacao experienced a decrease
in systolic and diastolic blood pressure
by 5 mm within two weeks.
A recent research
study conducted
by the Sahlgrenska Academy at University of Gothenburg
in Gothenburg, Sweden,
in collaboration with DuPont Nutrition & Health (DuPont), yielded breakthrough results demonstrating that probiotic intervention can alter and modify intestinal microbiota
in patients with colon cancer.
In a new study commissioned by The March of Dimes Foundation and published in Fertility and Sterility, researchers from The Hastings Center and Yale Fertility Center examined the practical circumstances of infertility treatment in the US that influence patients and their doctors to make treatment choices that too frequently result in multiple birth
In a new
study commissioned
by The March of Dimes Foundation and published
in Fertility and Sterility, researchers from The Hastings Center and Yale Fertility Center examined the practical circumstances of infertility treatment in the US that influence patients and their doctors to make treatment choices that too frequently result in multiple birth
in Fertility and Sterility, researchers from The Hastings Center and Yale Fertility Center examined the practical circumstances of infertility treatment
in the US that influence patients and their doctors to make treatment choices that too frequently result in multiple birth
in the US that influence
patients and their doctors to make treatment choices that too frequently result
in multiple birth
in multiple births.
He points to research
by a Stanford University researcher, Allan K. Mishra, who has
studied PRP for years, whose
in his most recent published research includes a large multicenter
study [8] involving a host of well - respected orthopedic surgeons around the country who followed 230
patients in a double - blind randomized control
study [the gold standard for medical research].
There is a particular focus on traditional foods as eaten all over the world
by people for thousands of years, as
studied by Dr. Weston A. Price
in the 1930s during his research
in traveling all over the world to determine the cause of degenerative illness
in his
patients.
Dr. Frederick Leickly, an allergist, writes
in his blog about a
study published
in the Journal of Allergy and Clinical Immunology (JACI) which concluded that a sensitization to fenugreek was believed to have been caused
by a peanut allergy
in patients.
For the purposes of this economic evaluation, the forms were initially used
in a related
study funded
by the National Institute of Health Research (NIHR) research for
patient benefit programme «assessing the impact of a new birth centre on choice and outcome of maternity care
in an inner city area,» which will be reported
in full elsewhere, comparing the costs of care
in a free standing midwifery unit with care
in an obstetric unit
in the same trust.16 The data collected included details of staffing levels, treatments, surgeries, diagnostic imaging tests, scans, drugs, and other resource inputs associated with each stage of the pathway through intrapartum and after birth care.
They know that birthing at home or
in a birth center with a trained midwife is a very safe option with lower rates of interventions and high
patient satisfaction but now you no longer have to search and search for
studies regarding homebirth which are often buried
by cultural anecdotes and message boards.
Physiologic
studies also have shown that healthy infants are able to protect their airways and do not have increased apnea when placed supine.20 Meyers and Herbst21 showed that the amount of gastroesophageal reflux
in healthy
patients was not significantly affected
by changes
in sleep position.
Diagnosis was always confirmed
by a physician, and breastfeeding information was always confirmed
by patients» mothers or other older close relative (as previously mentioned, this was not a requirement
in pediatric
studies).
Thus,
studies in which information about breastfeeding was not provided
by the mother of the
patient or an older close relative were assigned to the lowest quality group.
Previous research shows that giving an EPA - DHA supplement to
patients with cardiovascular disease reduces their chance of dying from the disease
by as much as 20 percent, authors note
in the
study, but supplementing with margarine didn't seem to cut it.
It's even more repulsive
in light of a recent
study by Dr. Andrew Chang of Albany Medical Center, published
in the Journal of the American Medical Association, showing opioids were no more effective at reducing pain for
patients with broken limbs than a high - dose combination of the over-the-counter, non-addictive painkillers ibuprofen and acetaminophen.
The push for the database stems from a
study published earlier this month
in the Annals of Internal Medicine which found 91 % of the 2,848
patients who had previously overdosed were later prescribed opioids
by their doctors.
Cori Gambini, president of Communication Workers of America Local 1168, says numerous
studies and reports, including one
in 2011
by the New England Journal of Medicine, show the adverse effects of putting too many
patients on too few nurses.
When residents move into the Eltona, they will participate
in a research
study performed
by the Mount Sinai School of Medicine tracking the health of asthma
patients.
Findings from a
study into Crohn's disease, led
by William G. Kerr, Ph.D., of SUNY Upstate Medical University, and his collaborators at the Erasmus Medical Center
in the Netherlands, provide the first evidence that
patients with debilitating inflammatory bowel disease lack sufficient quantities of a protein that comes from the SHIP1 gene.
A new international
study led
by University of Sydney has found that medication use increases
in newly diagnosed dementia
patients, particularly unnecessary or inappropriate medications.
The
study — led
by James Murrough, associate professor of psychiatry and director of the Mood and Anxiety Disorders Program at Mount Sinai — chose the epilepsy drug ezogabine, which was given to 18
patients in a pilot trial.
During this
in depth
study, an international team of researchers led
by British scientists investigated the impact of anti-hormone therapy on samples taken from
patients with prostate cancer.
The
study asserted that because of the number of complex provisions
in the law — such as the requirement that medication must be self - administered
by a mentally competent
patient — it will actually affect only a tiny fraction of seriously ill
patients.
To confirm the findings, the team
studied eight hips donated for research
by people with osteoarthritis and found the same results as
in the alkaptonuria
patient.
A new
study published
by researchers from the University of Illinois at Chicago suggests that the drug oseltamivir — commonly known as Tamiflu — does not cause an increased risk of suicide
in pediatric
patients.
Studies have found that people have an aversion to washed clothing worn
by murderers, and that they don't want an AIDS
patient to occupy a hospital bed after they've left it — implying a belief
in causality, which goes, weirdly, backward through time.
The
study adds to a growing body of research highlighting other cognitive functions affected
by aphasia, and indicates that the consequences of brain damage
in aphasia
patients may be more extensive than originally thought.
The
study by the Universities of Edinburgh and Glasgow followed
patients in Scotland over the course of a year following a severe form of stroke.
By comparison,
studies have reported that BDD is present
in about two percent of the general population, and
in up to ten percent of
patients seeking cosmetic procedures.
The
study included 3 992
patients who had a cardiac arrest outside hospital
in a large urban area and were treated
by physician - based emergency medical services between 2002 and 2011.
In 1999, a
study showed that the toxin can reduce migraines
by as much as 50 percent among
patients predisposed to them.
To
study the pathogenesis of HIV - induced PNS disease, Jamie Dorsey, Research Technologist, and the research team led
by Dr. Mankowski developed a simian immunodeficiency virus (SIV)- infected macaque model that closely reflects key peripheral nervous system (PNS) alterations seen
in HIV
patients with peripheral neuropathy.
Led
by Stella K. Kang, a radiologist with the Department of Radiology at the New York School of Medicine, the
study was designed to compare the effectiveness of a treatment algorithm for small renal tumors incorporating the nephrometry score, a renal tumor anatomy scoring system developed
by urologists, with the current standard of uniformly recommended partial nephrectomy
in patients with mild - to - moderate chronic kidney disease (CKD).
A new
study entitled «Oral Nutrition Supplements» Impact on Hospital Outcomes
in the Context of Affordable Care Act and New Medicare Reimbursement Policies» and conducted
by leading researchers at the University of Southern California, Stanford University, The Harris School at The University of Chicago and Precision Health Economics, and supported
by Abbott, found that the use of oral nutritional supplements decreased the probability of 30 - day hospital readmission, length of stay and costs among hospitalized Medicare
patients aged 65 and over.
«We are extremely encouraged
by the results of this
study and hope that this technology will be adapted for
patients for testing
in clinical trials
in the not - too - distant future.»
The researchers plan to expand their
study by examining how often the ALR SNPs they have identified occur
in patients with alcoholic liver disease compared to people without the disease.
Plastic surgeons and other cosmetic professionals are familiar with the challenges posed
by patients with body dysmorphic disorder (BDD) seeking cosmetic procedures, reports a survey
study in the February issue of Plastic and Reconstructive Surgery ®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
By taking a high - cost drug with a low - fat meal — instead of on an empty stomach, as prescribed — prostate cancer patients could decrease their daily dose, prevent digestive issues and cut costs by 75 percent, according to a new study in the March 28, 2018, issue of the Journal of Clinical Oncology (JCO
By taking a high - cost drug with a low - fat meal — instead of on an empty stomach, as prescribed — prostate cancer
patients could decrease their daily dose, prevent digestive issues and cut costs
by 75 percent, according to a new study in the March 28, 2018, issue of the Journal of Clinical Oncology (JCO
by 75 percent, according to a new
study in the March 28, 2018, issue of the Journal of Clinical Oncology (JCO).
By the early 1960s more than 1,000
studies on LSD and other hallucinogens discussing the experiences of 40,000
patients had been published
in reputable medical journals.