Six tissue types, they found, were significantly «undertargeted»
by pharmaceutical research: male reproductive tissues, embryonic structures, skin, cartilage, bone and lymph.
Not exact matches
In 1998, he spun ImmGenics
Pharmaceuticals out of
research at UBC and raised $ 20 million before the firm was acquired
by Abgenix Inc., a collaborator out of California.
But as if to advertise its success and thumb an unwrinkled nose at the government, in early November Allergan announced plans to build a US$ 12 - billion
research facility in New Jersey, a state with a big
pharmaceutical sector hurt
by the recession — and home to lots of rich housewives.
Epocrates (NASDAQ: EPOC; acquired
by Athenahealth in 2013), INC
Research (acquired
by Avista Capital Partners in 2010), Inspire
Pharmaceuticals (IPO 2000, ISPH), IntraLase (IPO 2004, ILSE), LenSx Lasers (acquired
by Alcon in 2010), Spinal Dynamics (acquired
by Medtronic in 2002), Spiration (acquired
by Olympus Medical Systems in 2010)
In 2008, workers at
pharmaceutical giant Pfizer's New London and Groton (Connecticut)
research and development campus raised the alarm: They were being replaced
by Indian workers on H - 1B visas and forced to train their replacements.
A March 28, 2018,
research note
by JMP Securities analyst Michael King indicated that at the recent International Symposium on Amyloidosis in Japan, Alnylam
Pharmaceuticals Inc. (ALNY: NASDAQ) reported multiple sets of results of clinical trials, separately evaluating its investigational RNA interference (RNAi) therapeutics patisiran and ALN - TTRsc02.
The global market for
pharmaceutical contract manufacturing, contract
research and contract packaging will grow from $ 136.4 billion in 2017 to $ 197.0 billion
by 2022 with a compound annual growth rate (CAGR) of 7.6 % for the period of 2017 - 2022.
The FDA is suppose to monitor «
research» on food and drugs and yet is largely funded
by the
pharmaceutical companies.
In an open letter to Theresa May, leading British scientists urged the home secretary to add an exemption for «
research pharmaceuticals being used to develop new medicines or progress neuroscience
research», so that new treatments and experiments were not brought to a halt
by the bill.
Over the past year, Kaloyeros has been working with local officials, including those at the Buffalo Niagara Medical Campus, to develop plans announced
by Cuomo in December to invest $ 50 million in state funds to build and equip a
pharmaceutical drug
research and development center at the downtown medical campus.
According to a 2008 poll of U.S. residents conducted
by Research!America, 94 % of Americans think universities and companies should work together to find new treatments, and 81 % think it's a good idea for
pharmaceutical companies to fund
research conducted in universities.
In medicine today, physician - scientists and basic scientists supplement support for their
research by applying their expertise part time to develop and test commercial products.1 In my own field, vision science, university - based researchers obtain additional funding through clinical and electrophysiologic studies, pathology, imaging, biochemistry, and animal model development performed for
pharmaceutical and instrument companies.
Although the
pharmaceutical industry, like the rest of the business world, has suffered a slowdown, the market
research company Frost and Sullivan still expects spending on drug discovery to expand from US$ 19.6 billion in 2002 to US$ 25.6 billion
by 2006, an annual growth rate of about 6 %.
Frustrated
by the lack of information available about industry
research at the university, Gervais's first insight into
pharmaceutical research came toward the end of his PhD studies at McGill University when he attended a seminar given
by invited speaker Don Nicholson, a senior director and head of biology at Merck Frosst Canada [Merck Frosst is sponsor of Next Wave Canada].
Although networking opportunities with other scientists might be fewer in large
pharmaceutical companies than they are in academia, the opportunity to publish postdoctoral
research results is offered
by some, but not all
pharmaceutical companies.
The
research was funded
by the National Institutes of Health, the Packard Award in Science and Engineering, Sanofi
Pharmaceuticals, Foxconn Technology Group, and the Hertz Foundation.
In 2012, we reported on plans
by pharmaceutical giant Hoffmann - La Roche to close its Nutley
research center, which for more than 80 years provided thousands of jobs to generations of scientists and other local residents.
In addition to a socially responsible mission, other advantages of working in the biotechnology and
pharmaceutical industry, as identified
by survey takers, were: engaging work and being part of cutting - edge
research and development; innovative, creative, and fast - paced work; and stability in difficult economic times, including generous salaries, benefits, and job security.
Lowe, a medical chemist
by profession, provides daily commentary on drug discoveries, the
pharmaceutical industry, and relevant
research and news, especially in chemistry.
CER professionals work mainly at academic institutions, but increasingly they are employed
by the
pharmaceutical industry, clinical
research organizations, and insurers, McDonald says.
If confirmed
by clinical
research, the data points to the possibility that early
pharmaceutical intervention could make a significant difference in the development of the disease.
Now, Wyss Institute researchers led
by Church have developed a new suite of such sensors, reported in Nucleic Acids
Research journal, that not only increase the number of cellular «switches and levers» that scientists can use for complex genetic re-programming, but also respond to valuable products such as renewable plastics or costly
pharmaceuticals and give microbes a voice to report on their own efficiency in making these products.
But hard - core allopathic medicine has its own hall of shame: profit - driven
research that virtually ignores unpatentable plant - based medicines, antibiotic overkill that yields invulnerable super-pathogens, and — according to a lead article in the April 15, 1998 issue of the Journal of the American Medical Association — an estimated 100,000 deaths a year in U.S. hospitals directly caused
by adverse reactions to
pharmaceutical drugs.
Studying how genes affect different drugs manufactured
by different companies gives Poirier greater influence on future drug development, he feels, which would not be possible if he was employed at any one
pharmaceutical research lab.
Other analysts have also noted that while
research and development spending
by pharmaceutical companies has increased dramatically, the number of new drug approvals has remained flat.»
The
research by Hart and Acs examines companies in a much broader range of science - and technology - based industries that are important to the American economy (and to the employment prospects of scientifically and technically trained people), including
pharmaceuticals, medical devices, optical equipment, industrial and agricultural chemicals, guidance and navigation systems, aeronautics and space, testing instruments, and much more.
«Because many broadly expressed genes that play key roles in essential cellular functions are under the control of cell - specific enhancers, the ability to affect enhancer function
by knocking down eRNAs could potentially provide a new strategy for altering gene expression in vivo in a cell - specific manner,» said Glass, noting that in his
research, anti-sense oligonucleotides were developed in conjunction with Isis
Pharmaceuticals, which suppressed enhancer activity and reduced expression in nearby genes.
These studies are often hampered
by incomplete health records, lack of uranium exposure data, and failure to detect residents who have moved, according to Johnnye Lewis,
research professor in
pharmaceutical sciences at the University of New Mexico in Albuquerque.
Prior
research that studied the effect of free behavioral counseling offered
by phone has shown improvement in smoking cessation rates when combined with
pharmaceutical interventions.
To carry out this project, the CeBiTec
research team cooperated with the University of Natural Resources and Life Sciences in Vienna (where the project was headed
by Professor Dr. Nicole Borth), the Austrian Centre of Industrial Biotechnology (acib), and two
pharmaceutical companies: Novartis (in Switzerland) and Pfizer (in the USA).
THE takeover of the British drugs company Wellcome
by its larger rival Glaxo will create a «leaner and fitter» company, but the nation's
research effort in
pharmaceuticals will suffer, a group of MPs say this week.
The Clinical
Research Forum, a consortium of leading academic health centers headed by Crowley, has asked pharmaceutical companies for a combined $ 10 million per year for 3 years (the minimum length of time the group expects NIH budget problems to persist), to create «bridging awards» for young investigators who have completed an NIH clinical research training grant, have narrowly missed receiving funding for an independent grant, and are employed at institutions that will match the funding and allow recipients to spend at least 75 % of their time on r
Research Forum, a consortium of leading academic health centers headed
by Crowley, has asked
pharmaceutical companies for a combined $ 10 million per year for 3 years (the minimum length of time the group expects NIH budget problems to persist), to create «bridging awards» for young investigators who have completed an NIH clinical
research training grant, have narrowly missed receiving funding for an independent grant, and are employed at institutions that will match the funding and allow recipients to spend at least 75 % of their time on r
research training grant, have narrowly missed receiving funding for an independent grant, and are employed at institutions that will match the funding and allow recipients to spend at least 75 % of their time on
researchresearch.
The United Kingdom is stepping in to protect an ailing
pharmaceutical research firm from attacks and intimidation
by animal rights protestors.
A large majority of AAPS members employed outside of academia (68 percent) are involved with a variety of specialties, led
by pharmaceutical development, biopharmaceutics / pharmacokinetics, and management / administration of
research and development.
Christopher Lane, Miller
Research Professor at Northwestern University, uses previously secret documents, many from the American Psychiatric Association archives, to support his argument that these decisions were marked
by carelessness, pervasive influence from the
pharmaceutical industry, academic politics and personal ambition.
Barry Schonwetter and colleagues at the Magainin
Research Institute, a private laboratory run
by the drugs company Magainin
Pharmaceuticals in Plymouth Meeting, Pennsylvania, took cells from the surface of cows» tongues and used organic solvents to extract several chemicals.
In the scope of our spin - off Braingineering Technologies Sarl, we will be developing technologies
by which we can provide the cultures for a fee to other labs or the
pharmaceutical industry for their
research.»
Adjoining properties have been reserved
by the County for the Palm Beach County
Research Village, future home of biotech and
pharmaceutical organizations, commercial interests, and residences.
With Helmsley funding, CCFA's
research consortium is now looking to identify potential therapies for development
by pharmaceutical companies while also conducting a rigorous investigation of the effect of diet on the microbiome and how that might allow patients to alter the course of their illness without taking medications.
PHILADELPHIA --(April 19, 2018)-- The Wistar Institute and partners at the Perelman School of Medicine at the University of Pennsylvania, Inovio
Pharmaceuticals, and GeneOne Life Science were recognized among the Top 10 Clinical
Research Achievement Awards by the Clinical Research Forum for their ground - breaking phase 1 DNA - based Zika vaccine research — the first trial of a Zika vaccine in humans, which proved safe and ef
Research Achievement Awards
by the Clinical
Research Forum for their ground - breaking phase 1 DNA - based Zika vaccine research — the first trial of a Zika vaccine in humans, which proved safe and ef
Research Forum for their ground - breaking phase 1 DNA - based Zika vaccine
research — the first trial of a Zika vaccine in humans, which proved safe and ef
research — the first trial of a Zika vaccine in humans, which proved safe and effective.
Recent past honorees include Julian Adams of Infinity
Pharmaceuticals, Alfred Goldberg of Harvard Medical School and Kenneth Anderson and Paul Richardson, both of Dana - Farber Cancer Institute, for the development of bortezomib, a drug that has altered the lives of hundreds of thousands of people with multiple myeloma; Alain Carpentier of Hôpital Européen Georges Pompidou in Paris and Robert S. Langer of MIT for innovations in bioengineering; and the work of Harald zur Hausen and Lutz Gissmann of the German Cancer
Research Center on human papillomavirus (HPV) and cancer of the cervix, which was recognized
by the WAFP prior to their receiving the Nobel Prize.
After receiving a master degree in Biotechnology at the University of Verona (Italy) in 1998, I joined the neuroscience centre of GlaxoSmithKline (GSK), a large
research - based
pharmaceutical company based in Verona (Italy) and Harlow (UK), where I pioneered the use of functional magnetic resonance imaging (MRI) to describe the neural substrates modulated
by pharmacological agents, a line of
research that I also pursued to obtain a PhD degree in biomedical imaging with the University of Verona.
The first estrogen bioassay, (a bioassay is a measurement of the potency of a substance
by its effect on living cells or tissues), is developed for use in
pharmaceutical research.
In addition to conducting and funding
research to develop more effective and safer therapies, NCI has thriving
research programs in critically important areas like survivorship, delivery of care, primary prevention, screening, and quality of life — areas that are not traditionally supported
by the private sector because they have limited commercial value or are not a good fit with traditional
pharmaceutical and biotech business models.
Together, this translational program is developed within the National Cancer and Cognition Platform (CNO / Ligue Nationale contre le cancer), with the aim to collaborate in a structured way with French oncology groups,
research teams as well as
pharmaceutical industry,
by providing preclinical models and guidance on standard operating procedures for ancillary or future studies in identified population at risk.
We collaborate with academic and corporate
research and development organizations to characterize conditions mediated
by senescent cells, and to identify
pharmaceutical candidates that may control or ameliorate such conditions and increase healthspan.
Dr. Robert Urban of Johnson & Johnson will address how Organ - Chips are being used
by the
pharmaceutical industry today and the potential the technology holds to change the drug development process and reduce the use of animals in
research.
Kala
Pharmaceuticals (KALA) Upgraded to Hold
by Zacks Investment
Research - The Lincolnian Online
Research project ideas can be proposed
by Member Institution PI's to Takeda
Pharmaceuticals via submission of one or more concept proposals.
Funding: The
research described in this manuscript was funded
by High Point
Pharmaceuticals LLC.