Sentences with phrase «by phosphatidylinositol»

Regulation of muscle protein degradation: coordinated control of apoptotic and ubiquitin - proteasome systems by phosphatidylinositol 3 kinase

Here's the scientific description: «In this process, the capsaicin receptor (TRPV1) is sensitized by phosphatidylinositol -4,5-bisphosphate (PIP2) hydrolysis following phospholipase C activation.»

Not exact matches

The protein encoded by the PIK3C2G gene belongs to the phosphatidylinositol -4,5-bisphosphonate 3 - kinase (PI3K) family, which plays a critical role in cancer.28 Experimental evidence suggests that activation of PI3K signaling enhances production of COX - 2 and PGE2, which results in inhibition of apoptosis in colon cancer cell lines that can be restored with NSAID - mediated blockade of PI3K.29

The membrane associated adaptor ankyrin - B (AnkB) promotes fast axonal transport and elongation by coupling dynactin to multiple organelles through binding to phosphatidylinositol 3 - phosphate lipids in these cargos.

Interestingly, PDGF - BB overexpression by modified hDPSCs enhanced the recruitment of hDPSCs both in vitro and in vivo via the activation of the phosphatidylinositol 3 kinase (PI3K) / Akt signaling pathway and, in combination with secreted vascular endothelial growth factor (VEGF), enhanced in vitro angiogenesis.

Antigen - specific enhancement of natural human IgG antibodies to phosphatidylcholine, phosphatidylglycerol, phosphatidylinositol -4-phosphate, cholesterol, and lipid A by a liposomal vaccine Containing lipid A.Vaccine.

The phosphatidylinositol pathway, on the other hand, is triggered by the Gq - coupled receptors.

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate - 1 (IRS - 1)- associated phosphatidylinositol 3 - kinase activity in muscle.

METHODS: We treated 3T3 - L1 adipocytes with 2.5 mmol / l R (+) alpha - lipoic acid for 2 to 60 min, followed by assays of: 2 - deoxyglucose uptake; glucose transporter 1 and 4 (GLUT1 and GLUT4) subcellular localization; tyrosine phosphorylation of the insulin receptor or of the insulin receptor substrate - 1 in cell lysates; association of phosphatidylinositol 3 - kinase activity with immunoprecipitates of proteins containing phosphotyrosine or of insulin receptor substrate - 1 using a in vitro kinase assay; association of the p85 subunit of phosphatidylinositol 3 - kinase with phosphotyrosine proteins or with insulin receptor substrate - 1; and in vitro activity of immunoprecipitated Akt1.

I think if you benefit from it it suggests you are probably deficient in a number of other phospholipids to, eg phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine, and would benefit by eating phospholipid rich foods like liver, brain, marrow, and egg yolks.