Sentences with phrase «by plaque which»

It's caused by plaque which can lead to gum disease.

Not exact matches

This effect was thought to be achieved by protecting the cholesterol from oxidation which is a common cause of arterial plaque build - up (13).

It interferes with saliva production, which naturally cleanses the mouth by neutralizing acids caused by plaque and washing away dead cells building up in the mouth.

BY ANDY HUMM The Stonewall Inn bar ---- the 1969 raid on which sparked the modern LGBT liberation movement ---- is on a street renamed Stonewall Place and was made an official National Historic Landmark in 2000, but it does not have an official plaque marking its role in history.

It causes the build - up of plaques, which some researchers think cause Alzheimer's by killing cells.

But in Alzheimer's, the APP's function is sabotaged by zinc, which accumulates in the disease's trademark plaques (Cell, DOI: 10.1016 / j.cell.2010.08.014).

In a brain ravaged by Alzheimer's, microtubules, which are crucial to cell communication, disintegrate as tau proteins (blue) form tangles and amyloid proteins (green) form plaques.

The test, which measures beta amyloid plaque levels in cerebrospinal fluid, successfully diagnosed 15 Alzheimer's patients and wasn't tripped up by 19 people with other neurological diseases.

Plaque hinders neuronal activity by gumming up synapses (spaces between cells through which chemical or electrical information is transmitted), eventually damaging nerve cell branches and leading to neuronal death.

At the time, the mechanism by which the plaques were being removed was not clear.

Some 500,000 people die in the United States each year from coronary heart disease, which is usually caused by heart arteries getting clogged with fatty plaque.

We get heavily hyped drugs like Avastin, which shrank tumors without adding significant time to cancer patients» lives (and increased the incidence of heart failure and blood clots to boot); Avandia, which lowered blood sugar in diabetics but raised the average risk of heart attack by 43 percent; torcetrapib, which raised both good cholesterol and death rates; and Flurizan, which reduced brain plaque but failed to slow the cognitive ravages of Alzheimer's disease before trials were finally halted in 2008.

They also showed in mice studies and in the laboratory that NCAM2 was broken down by another protein called beta - amyloid, which is the main component of the plaques that build up in the brains of people with the disease.

The drug also appeared to reduce the amount of the protein amyloid beta (which forms toxic plaques in the brains of Alzheimer's patients) by decreasing the levels of metals such as zinc and copper.

Alzheimer's disease, a major source of dementia and memory loss in the elderly, is caused by the accumulation of protein plaques which choke neurons in the brain.

AD is characterized by plaques composed of amyloid β - protein (Aβ) and tangles composed of Tau protein; accumulation of Aβ protein leads to disruption of Tau and, eventually, neurodegeneration which affects brain regions in a variety of ways.

In contrast to the plaques which are typical for the disease discovered by Alois Alzheimer more than 100 years ago, the fibril structure now uncovered can not be directly observed under the light microscope.

«The activity of the microglia is stimulated by dying brain cells, not by the deposits of amyloid proteins, called plaques, which also occur in Alzheimer's disease,» Haass notes.

The nature of those plaques finally came into focus in 1984, when George Glenner, a research scientist at the University of California, San Diego, identified the peptide called amyloid - beta and hypothesized that Alzheimer's was caused by «amyloidosis» of the brain, a process in which insoluble forms of an amyloid protein accumulate.

Song's work joins that of researchers at the Salk Institute who, last year, discovered that boosting the level of a protein known as Neuregulin - 1 can help fight Alzheimer's by upping the levels an enzyme called neprilysin, which in turn breaks up plaques.

This project is relevant to Alzheimer's and Parkinson's diseases in defining the mechanisms by which amyloid plaques and other insoluble aggregates form in brain tissue.

Yury Miller, M.D., Ph.D., a Professor of Medicine at UC San Diego School of Medicine, will investigate disease - promoting and protective mechanisms by which cholesterol regulates macrophages within atherosclerotic plaques.

Health improvement (allowing to post - pone / escape the diseases and thus live, healthier / disease - free longer, but not above human MLSP of around 122 years; thus these therapies do not affect epigenetic aging whatsoever, they are degenerative aging problems not regular healthy aging problem (except OncoSENS - only when you Already Have Cancer - which cancer increases epigenetic aging, but cancer removal thus does not change anything / makes no difference about what happens in the other cells / about what happens in the normal epigenetic «aging» course in Normal non-cancerous healthy cells) Although there is not such thing as «healthy aging» all aging in «unhealthy» (as seen from elders who are «healthy enough» who show much damage), it's just «tolerable / liveable» enough (in terms of damage accumulating) that it does not affect their quality of life (enough yet), that is «healthy aging»: ApoptoSENS - Clearing Senescent Cells (this will have great impact to reduce diseases, the largest one, since it's all inflammation fueled by the inflammation secretory phenotype (SASP) of these senescent cells) AmyloSENS - Dissolving the Plaques (this will allow humans to evade Alzheimer's, Parkinsons and general brain degenerescence, allowing quite a boost; making people much more easily reach the big 100 - since the brain is causal to how long we live; keeping brain amyloid - free and keeping our memories / neuron sharp / means longer LongTerm Potentiation - means longer brain function means longer heavy brain mass (gray matter / white matter retention seen in «sharp - witted» Centenarians who show are younger brain for their age), and both are correlated to MLSP).

At 13 months of age, the intracellular MOAB - 2 immunolabel was hardly detectable in pyramidal neurons adjacent to amyloid plaques, the latter which were strongly labeled by this antibody and not by pab27576 (Additional file3: Figure S2 a-b).

Also centenarian cardiac senyle amyloidosis (transthyretin) which kills supercentenarians from this plaque in their hearts, will be reduced by this therapy since it shares similar mechanism as amyloid and parkin (son).

This technique allowed the detection of C - terminally truncated peptides, including Aβ38, Aβ39, Aβ40 and Aβ42 species, as early as 3 months of age; a time point which precedes amyloid plaque deposition by several months (4 — 6 months).

While the negative effect of plaques and tangles on neurons is apparent, the exact mechanism by which these lesions cause dementia is still under investigation.

All are known to lower the risk of heart problems, like plaque buildup in the arteries or arrhythmia, which is characterized by an irregular heartbeat.

They contain Omega - 3 fatty acids, which can help increase your (HDL) good cholesterol by slowing down the growth of plaque into the arteries and can prevent blood clots that can lead to strokes or heart attacks.

I have atherosclerosis and am attempting to remove the artery plaque via the plant based diet prescribed by Caldwell Esselstyn (and Dean Ornish), which is vegan with strictly no sugars, oils, or fats apart from ground flaxseeds.

It is caused by atherosclerosis, or hardening of the arteries, which occurs when plaque from cholesterol and other substances accumulate in the arteries.

Earlier lab work by the researchers helped explain key mechanisms involved with assisting vitamin D3 to clear the abnormal protein amyloid - beta, which is found within the plaque.

The researchers discovered signaling networks and key genes regulated by the omega - 3 fatty acid DHA and also vitamin D3 which can help manage inflammation and greatly boost plaque clearance.

Oxidized lipids promote arterial plaque formation by activating the immune response, which promotes inflammation and attracts white blood cells to engulf and contain the damaged molecules.

To me it seem like plaques form when the blood becomes «saturated» with cholesterol and it «precipitates» out in the walls of the arteries where it is eaten by immune cells which turn into foam cells when they become engorged with cholesterol.

Alzheimer's disease, which is characterized by a loss in motor, psychological, and cognitive function, is attributed to the build up of beta - amyloid plaque surrounding neurons.

Furthermore, high LDL appears to be a sign of cholesterol sulfate deficiency — it's your body's way of trying to maintain the correct balance by taking damaged LDL and turning it into plaque, within which the blood platelets produce the cholesterol sulfate your heart and brain needs for optimal function.

See, the nerve roots, which are most commonly associated with sciatic pain, are supplied by some of the arteries most vulnerable to atherosclerotic plaque formation.

Chia is rich in Zinc which prevents tartar by keeping plaque from mineralizing on your teeth and has an antibacterial effect that keeps bad breath germs away.

CVDs typically develop over decades, characterized by arteries that clog and harden from plaque deposits in which calcium is the main mineral component.

This MD in Australia talks about cholesterol and the fact that the way it is tested today is incomplete and does not tell the whole story when you just look at A1c, LDL, HDL, and Triglycerides, this diet raises your cholesterol but there is a small dense LDL that is not accepted by the liver for servicing but rejected and ends up in your arteries as plaque... and this is what needs to be included in a Lipid panel because this diet pre-diet shows a lipid panel that is not to bad but when you look at the SDLDL it is at 20 which is very high, and when on this diet for 6 or more weeks your lipid panel is higher but the SDLDL is 0 Zero... so your doctor flips out and yells at you but in fact you are much less prone to heart failure...

A seven - disc trilogy Blu - ray set with all three movies also hits the shelves on the same day, which includes a plaque of photos signed by director Michael Bay.

BONUS: In a tribute to «The Maltese Falcon,» (which was not filmed in San Francisco), a plaque on Burritt Street commemorates the plot's fictional death with the words, «On approximately this spot Miles Archer, partner of Sam Spade, was done in by Brigid O'Shaughnessy.»

The exterior of the 911 Turbo S Exclusive Series is completed by the «Porsche Exclusive Manufaktur» plaque on the sides of the car and the «Exclusive Series» logo on the central air intake on the rear lid, which has also been manufactured from carbon fiber.

The absence of rear seats serves as a further pointer to the car's radically sporty character which is further emphasized by the numbered plaque fixed to the centre console.

The centre console is distinguished by the car's individually - numbered metal plaque, and by a unique carbon - effect finish to the bezel which carries a distinctive RS pattern.

Personally, I would use dentistry to correct any rotten or painful teeth, followed by a good quality raw diet, and an all - natural water additive called Healthy Mouth (which kills off plaque forming bacteria).

Caused by bacteria which, if left unchecked, form a layer of a sticky residue called plaque over the teeth of an animal, Periodontal disease (PD), will often begin very early in a pet's life.

Dental disease begins with formation of a film on the tooth surface, which is is produced by bacteria called plaque.

The gums are receding because they are attached to the bone, which is being dissolved by the «war» between the white blood cells and the bacteria growing in the plaque beneath the gum line.