Sentences with phrase «by pseudogenes»

Many of the new proteins encoded by pseudogenes could also be traced in other cancer cell lines, and the next objective on the researchers» agenda is to investigate if these genes in the» junkyard» of the genome play a role in cancer or other diseases.

However, the same Yale lab reports in a separate paper published in the Proceedings of the National Academy of Sciences dramatic differences between species in genomic regions populated by pseudogenes, molecular fossils of working genes.

Not exact matches

Tangible proof can be found by studying vestigial features, ebryonic development, biogeography, DNA sequencing, pseudogenes, endogenous retroviruses, labratory direct examination of natural selection in action in E-Coli bacteria, lactose intolerance in humans, the peppered moth's colour change in reaction to industrial pollution, radiotrophic fungi at Chernobyl... all of these things add to the modern evolutionary synthesis.

Comparisons with the chimpanzee genome indicate that human SIGLEC11 emerged through human - specific gene conversion by an adjacent pseudogene.

A human - specific gene expressed only in glial cells of the brain apparently arose from conversion of the ancestral gene by a nonfunctional pseudogene in a common human chimp ancestor.

These issues include the presence of a large number of highly homologous sequences in other genomic regions and the frequent sequence exchange between active and pseudogenes, together with the high frequency of negative staining of PMS2 by immunohistochemistry.

This information would then be added into the core Ensembl gene - set (the reference zebrafish genome used by researchers around the world) in such a way as to increase the quantity and quality of the gene - set without adding artifacts or pseudogenes.

Most VSG genes are pseudogenes, which may be used to generate expressed mosaic genes by ectopic recombination.

By comparing the promoter sequences of expressed with non-expressed OR and VR genes and pseudogenes, it may now be possible to identify key genomic motifs that control receptor choice.

Alternatively, they could be expressed at a different age [23], or they may be cryptic pseudogenes that have disrupted promoter elements and thus are no longer recognized by the machinery regulating olfactory receptor choice.

The olfactory (OR) and vomeronasal receptor (VR) repertoires are collectively encoded by 1700 genes and pseudogenes in the mouse genome.