Sentences with phrase «by reactive oxygen»

Alpha Lipoic Acid Monograph Alternative Medicine Review 1998 (Aug); 3 (4): 308 — 311 ~ FULL TEXT Acting as a potent antioxidant, DHLA was found to protect rat pancreatic islet cells from destruction by reactive oxygen species.

Antioxidants are nature's way of providing your cells with adequate defense against attack by reactive oxygen species (ROS).

[i] In this theory, he declared that ageing is caused by reactive oxygen species accumulating within cells.

Berries are high in proanthocyanins the bioflavanoid pigments that protect our cardiovascular systems from destruction by reactive oxygen species (ROS).

It boosts the immune system, protects vision, stops the build - up of oxidised fats, and helps to convert carbohydrates into energy and most crucially reduces the damage done to important cell components caused by reactive oxygen molecules such as free radicals and peroxides7.

So by replacing carbs with healthy fats, your cells» mitochondria are less likely to suffer damage from free radicals that are caused by reactive oxygen species or ROS.

Oxidative stress is generated by reactive oxygen species (ROS) produced in response to metabolic activity and environmental factors.

So while it's true that organisms living deep in the Earth are not exposed to the high - energy radiation found when you travel between planets or more hypothetically between stars, the systems that cells have evolved to repair damage done by reactive oxygen species will be useful whether they arise from rocks or from cosmic rays.

These single strands are particularly vulnerable to assaults by reactive oxygen species — toxic byproducts of respiration — that could cause changes in the genetic information they contain.

As we age, the nitric oxide meant to cause dilation is increasingly destroyed by reactive oxygen species such as superoxide, which are produced by many components of our body's own cells, including organelles called mitochondria.

In medicine, they could also be used to encapsulate oxygen - sensitive active compounds and to reduce the inflammation caused by reactive oxygen species (ROS) in biomedical applications.

Not exact matches

Curcumin exerts both direct and indirect antioxidant effects by scavenging reactive oxygen species (ROS)(38) and inducing the expression of cytoprotective proteins in an Nrf2 - dependent way (39).

This causes the battery to overheat in the presence of its reactive lithium electrolyte and possibly catch fire (which is exacerbated by oxygen entering from outside).

In the case of cisplatin - induced hearing loss, kenpaullone appears to protect hair cells by preventing CDK2 from stimulating the production of toxic reactive oxygen species from the cells» mitochondria.

We live in an oxygen - rich atmosphere, and radicals, particularly reactive oxygen species (ROS), are natural by - products of respiration.

Oxygen atoms are highly reactive, yet the world does not spontaneously burn, even though everything is surrounded by this aggressive element.

This new paper, published in the journal Applied and Environmental Microbiology, demonstrates that MRSA die on copper surfaces by a multifaceted attack from copper ions and reactive oxygen species (ROS).

Some experts blame aging on the corrosive capability of chemically reactive oxygen molecules or «oxidants» churned out by mitochondria inside cells.

«Muscles maintain proper function by producing reactive oxygen species at the right time: Study results underscore the importance of having a nuanced view of antioxidants.»

Although reactive oxygen species can damage cells when produced in high amounts, according to a study published online Sept. 5, 2017 by Science Signaling and featured on the journal's cover, these oxidative species are crucial signals that start the process of repairing myofiber.

Mitochondria help injured muscle cells (myofibers) repair by soaking up calcium that enters from the site of injury and using it to trigger increased production of reactive oxygen species.

«Energy production can also generate reactive chemical species — often referred to as «reactive oxygen species» or «oxidants» — as by - products, which can be damaging to cells.

In a third study published online by Science on 6 April (www.sciencexpress.org), molecular geneticist Valter Longo of the University of Southern California in Los Angeles and colleagues battered a population of yeast mutants with heat or paraquat, a chemical that creates reactive oxygen molecules.

That light is absorbed by the chlorine - based molecules, which then excite nearby oxygen molecules, creating a highly reactive form of oxygen, known as singlet oxygen, that rips apart nearby biomolecules and kills the tumor cell.

Scientists do not yet fully understand how antibiotics work on the molecular level, but they think that the drugs are effective in part by introducing reactive oxygen to bacterial cells, which damages key cellular structures.

Oxidative states are generally considered to be indicative of cellular stress; however, cells inherently release harmful reactive oxygen species during energy production, neutralized by intracellular antioxidative buffering systems.

The Einstein team suspected that cysteine was helping to kill TB bacteria by acting as a «reducing agent» that triggers the production of reactive oxygen species (sometimes called free radicals), which can damage DNA.

Like a molecular thermostat, NPR1 senses changes in the «tick - tock» of the plants» reactive oxygen species clock, and responds by turning up both the «morning» and the «evening» genes in the other clock.

The cell envelops the foreign body and exterminates it specifically by using reactive oxygen species (ozone, hydrogen peroxide, bleach), generated thanks to the enzyme NOX2.

When O3 interacts with a metal oxide (Mn / TiO2), O3 is decomposed by the following reactivity formula on the surface of manganese, generating reactive oxygen species, i.e., oxygen radical.

Calorie restriction with proper nutrition seems to help extend lifespans and delay the onset of age - related disorders by reducing what are called reactive oxygen species in the body.

Oxidative stress reflects an imbalance between the reactive oxygen that is generated by normal cell metabolism and the cell's ability to handle toxic byproducts from that metabolism.

Technology such as this, scientists said, may have a promising future in the identification and surgical removal of malignant tumors, as well as using near - infrared light therapies that can kill remaining cancer cells, both by mild heating of them and generating reactive oxygen species that can also kill them.

Consequently, massive amounts of reactive gases such as oxygen, hydrogen, and methane are continually being added to Earth's now «anomalous» atmosphere faster than they would otherwise be removed by inorganic chemical processes.

The finding suggests that microbes with the ability to produce oxygen were prolific at least locally around 3.46 billion years ago, releasing large quantities of this reactive molecular gas into the oceans and eventually the atmosphere by the end of this period (more).

Now in a study published in the journal Scientific Reports, Alexander Zaika, Ph.D. and coworkers show that DNA damage in the esophageal cells caused by acidic bile reflux (BA / A) activates enzymes called NADPH oxidases in the mitochondria, the cell's power house, to release highly reactive - oxygen species (ROS).

STEVEN BENNER: Radiation causes damage to DNA by way of specific molecules, in particular, reactive oxygen species.

Abstract: Gain - of - function mutations in the presenilin - 1 (PS - 1) promote Alzheimer's disease (AD) by increasing reactive oxygen species, at least part of which is derived by an accompanying increase in generation of amyloid - β (Aβ).

Gain - of - function mutations in the presenilin - 1 (PS - 1) promote Alzheimer's disease (AD) by increasing reactive oxygen species, at least part of which is derived by an accompanying increase in generation of amyloid - β (Aβ).

A Emory News item on a helpful part of the microbiome focuses on how the same type of bacteria â $ «lactobacilli â $ «activates the same ancient signaling pathway in intestinal cells in both insects and mammals. It continues a line of research from Rheinallt Jones and Andrew Neish on how beneficial bacteria stimulate wound healing by activating ROS (reactive oxygen species).

* p < 0.05, (B) Induction of reactive oxygen species (ROS) by HPP compounds in HepG2 cells.

A child's heart is more sensitive to injury caused by interrupting blood flow during surgery, and excess reactive oxygen species are a key source of this damage.

Davis and his colleagues are able to shut off cheap oakley reactive oxygen species at the source by targeting the NOX (NADPH oxidase *) enzymes that produce them.

This primary response involves the production of reactive oxygen species (ROS), which are molecules that can act like tiny bombs when released by the plant cell at the offending pathogen.

At the cellular level, p53 can either induce senescence or, of major interest here, inhibit senescence by controlling both reactive oxygen species (ROS) levels and a signaling pathway mediated by protein kinases AMPK and mammalian target of rapamycin (mTOR).

The free radical theory hypothesizes that gradual accumulation of mutations in mitochondrial DNA caused by formation of reactive oxygen species (ROS) is a major contributor.

Many chemotherapy drugs and radiation treatments actually kill cancer cells in part by raising levels of reactive oxygen.

15 - deoxy - Δ12, 14 - prostaglandin J2 (15d - PGJ2), a prostaglandin derivative, has shown its anti-tumor activity by inducing apoptosis through reactive oxygen species (ROS)- mediated inactivation of v - akt, a murine thymoma viral oncogene homolog, (AKT) in cancer cells.

The expression of micro-RNA miR - 663 was induced by mitochondrial reactive oxygen species production, an apoptotic signal and oxidative stress response, and miR - 663 induced the expression of nuclear - encoded mitochondrial respiratory chain subunits.

We describe Eros (essential for reactive oxygen species), a protein encoded by the previously undefined mouse gene bc017643 , and show that it is essential for host defense via the phagocyte NAPDH oxidase.