Sentences with phrase «by real factors»

Being attached by real factors like the number of child you really dream of having some exactly sexually encouraging, but finding by breast size or big matched build on sexual interests definitely is.

Not exact matches

Sure, there are many other factors affecting this trend besides on - line merchandising — most notably real estate firms which have accelerated neighborhood declines by escalating rents — but those factors combined have decimated downtown and suburban shopping areas and have had a major impact on our way of life.

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

But where the Gear Fit was hampered by its sole focus on fitness, the Gear S takes advantage of the curved form factor and extra screen real estate to create full - featured smartwatch that is truly Samsung's best yet.

Actual results could differ materially from those expressed in or implied by the forward - looking statements contained in this release because of a variety of factors, including conditions to, or changes in the timing of, proposed real estate and other transactions, prevailing interest rates and non-recurring charges, store closings, competitive pressures from specialty stores, general merchandise stores, off - price and discount stores, manufacturers» outlets, the Internet, mail - order catalogs and television shopping and general consumer spending levels, including the impact of the availability and level of consumer debt, the effect of weather and other factors identified in documents filed by the company with the Securities and Exchange Commission.

However, a large literature concludes that the equilibrium real short - term rate is very unlikely to be constant, with its value affected by many factors, including the pace of technological change, fiscal policy and the evolution of financial conditions.3

Mladina used a modified version of the Fama - French five - factor model to evaluate how well the returns and risks of publicly traded equity REITs and private real estate investments are explained by common stock and bond factors.

By scoring BTC and ETH through these attributes, teams were able to objectively manage data into their case studies, along with other real world factors such as commercial application, and projected growth affected by various trends in the crypto worlBy scoring BTC and ETH through these attributes, teams were able to objectively manage data into their case studies, along with other real world factors such as commercial application, and projected growth affected by various trends in the crypto worlby various trends in the crypto world.

CenterSquare aims to uncover low relative price opportunities across sectors and at different turning points in the real estate cycle by looking beyond the obvious factors of stock price and underlying real estate value.

The Toronto real estate market is being driven by these major factors.

Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commfactors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commfactors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commfactors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange CommFactors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.

Real estate is local though prices are also impacted by national and global factors — such as monetary policies and offshore investors who consider US housing as an asset class and escape route — as well as by local factors.

I wonder if these results from the recent Pew poll of attitudes toward religion in public life don't foretell a real change, however partial, however qualified by any number of other factors.

Part of the confusion of Cobb's position stems from the fact that the extensive continuum, conceived of as a set of relations underlying past, present, and future, is part actual and part potential — actual in as far as it is constituted by actual entities enjoying actual relationships legislating what are real potentialities governing the relationships of future occasions; and merely potential in so far as these relationships are viewed as factors determining what forms of definiteness are, and are not, possible as factors in future fact.

The faith - group programs, representing Protestant, Catholics, and Jews, have consistently provided documentaries, dramas, and discussions which dealt with issues almost never touched by commercial broadcasting: the economic factors behind nuclear armaments; the issues behind draft evasion (during the Vietnam War); the real causes of worldwide starvation; and the problems of people who are ignored almost completely by the media, such as the aging who can not live on their pensions, unwed mothers, farm workers who have no homes, undocumented aliens whom we wish to employ but not pay, and refugees we are sending back to certain death in their own countries.

In itself, creativity is the «protean» factor in an actual entity that needs to be characterized by eternal objects before it can be said to be real.

Moreover, from the Whiteheadian point of view one has to recognize that the evolving events — actual animals and plants as we meet them in real life — are influenced by environmental factors as well as genetic.

By abstracting from all these other complicating factors, most of which involve subjectivity in one way or another, Emmet may enable us to appreciate a strand of real causal effectiveness within concrescence.

Therefore when He becomes man, it will need a real co-operation from one parent - the woman - since there must be a vehicle of enfleshment to make the Incarnation possible while excluding the determining factor of the male by which the Incarnation would have been an event subject to human will, thus bringing about a human person.

The «Cool Factor» — It's very real: Driven by the cult - like popularity of our T - shirts, strong sales of Greene Turtle merchandise provide a valuable added revenue stream.

It's also a good thing that athletes don't have boards of directors or any contingency plans designed to reduce the «hit by a bus» factor that real companies have.

Whether that's a telling factor in Neymar's reported desire to move on is unclear, but as per Don Balon, as re-reported by The Express, Messi has warned his former Barcelona teammate not to use the Catalan giants as a tool in his bid to get a big contract from Real Madrid.

Reus, who worked with Klopp at the Westfalenstadion, is being watched by both Liverpool and Real Madrid, but the pair's past relationship may play a deciding factor in the player's future should he decide to quit the Bundesliga.

My experience with the Newcastle football team in Oklahoma leads me to believe that, as long as impact sensors are strictly used for the limited purpose of providing real - time impact data to qualified sideline personnel, not to diagnose concussions, not as the sole determining factor in making remove - from - play decisions, and not to replace the necessity for observers on the sports sideline trained in recognizing the signs of concussion and in conducting a sideline screening for concussion using one or more sideline assessment tests for concussion (e.g. SCAT3, balance, King - Devick, Maddocks questions, SAC)(preferably by a certified athletic trainer and / or team physician), and long as data on the number, force, and direction of impacts is only made available for use by coaches and athletic trainers in a position to use such information to adjust an athlete's blocking or tackling tec hnique (and not for indiscriminate use by those, such as parents, who are not in a position to make intelligent use of the data), they represent a valuable addition to a program's concussion toolbox and as a tool to minimize repetitive head impacts.

In Chicago, the Park District will use a new high - tech system that uses computer software to give real - time predictions of bacteria counts based on such factors as water temperature, modeling of the lake bottom and wave action monitored by buoys.

Trust me when I say I was cursing the fact that no one knows the real risk factors for SIDS and I wasn't comfortable with my child sleeping on her stomach in her own sleeping space because she hated and fought her swaddle, had an intense Moro reflex, and the gas would've been soothed by tummy sleep.

My hope here is that by looking at the research that is being used to form opinions on bedsharing, I can show you what is involved in the research and allow you to come to your own conclusion about the real risks inherent in bedsharing versus the risks of other factors interacting with bedsharing.

The use of LLC's by a real estate company Glenwood Management, and it's billionaire CEO Leonard Litwin, has factored in to high profile federal corruption cases against the two former leaders of the legislature.

Participants took part in a real - time electronic poll which explored their views on a series of issues relating to their profession: Among the results were: over three quarters of BME teachers considered themselves to be ambitious, yet stated they are being held back by racial discrimination, and the attitude of senior colleagues; nearly two - thirds (62 %) of BME teachers felt their school or college was not seriously committed to addressing their professional development needs and aspirations; 63 % of BME teachers said their employers were not committed to ensuring their mental and physical wellbeing at work, with workload cited as the single most negative factor impacting on their wellbeing; the vast majority of BME teachers felt the Government does not respect and value teachers and does not understand the day to day realities of teaching (99 %); three quarters of BME teachers said they were not confident that their headteacher will make professional and fair decisions regarding their future pay.

Whilst our initial mission to rid Afghanistan of al - Qaeda was laudable and understandable, our policy since has been undermined by two factors — lack of clarity as to the continuing mission, and subsequent confusion as to our real enemy.

The study concluded finally that the Bradley effect was a real phenomenon, amounting to a median gap of 3.1 percentage points before 1996, but that it was likely not the sole factor in those discrepancies, and further that it had ceased to manifest itself at all by 1996.

«At worst the amount of galactic real estate favorable to life is reduced by a factor of two or three,» he says.

You might think that plants grow according to how much nutrition, water and sunlight they are exposed to, but new research by Dr Nick Pullen and a team from the John Innes Centre, UK shows that the plant's own genetics may be the real limiting factor.

Co-author Dr Jon Simons adds: «By recognising and addressing these psychological factors head - on, not only can we come to understand obesity better, but we may enable the creation of interventions that can make a real difference to health and wellbeing.»

Based on the principle of a time lens2, which stretches the timescale by a factor of 100 while increasing resolution, this new method has enabled researchers to observe giant light pulses in real time, with an intensity 1,000 times greater than that of the initial fluctuations from the light source, a laser.

Incorrect guesses in the real games could be caused by several factors, the most likely being uncertainty about whether a phosphene had appeared.

Reference article: The transcription factor GATA6 enables self - renewal of colon adenoma stem cells by repressing BMP gene expression Gavin Whissell, Elisa Montagni, Paola Martinelli, Xavier Hernando - Momblona, Marta Sevillano, Peter Jung, Carme Cortina, Alexandre Calon, Anna Abuli, Antoni Castells, Sergi Castellvi - Bel, Ana Silvina Nacht, Elena Sancho, Camille Stephan - Otto Attolini, Guillermo P. Vicent, Francisco X. Real and Eduard Batlle Nature Cell Biology (2014) Doi: 10.1038 / ncb2992

While the Keck Telescopes gather more light, have the best instruments, and are hosted by the best site in the world, the real X Factor comes from the astronomers whose creativity constantly pushes the limits of what is possible.

The real question is which factor is doing the heavy lifting — and a new report in Nature released Wednesday says that on the Antarctic Peninsula, at least, human - generated greenhouse gases have almost certainly been by far the most important driver of warming over the past half - century.

There's also speculation that repetitive brain injuries — such as those sustained by Ali over his long boxing career — might be a risk factor for Parkinson's, but there's no real evidence to back this up.

Timothy S. Harlan, MD, a nutrition specialist and assistant professor of internal medicine at the Tulane University School of Medicine in New Orleans, says that while diet - soda dependence appears to be a real phenomenon, it is probably caused by a complex mix of behavioral factors, not necessarily artificial sweeteners.

I believe that nutrition has some influence on the disease course, but as MS is a multifactoral illness (genetic AND SEVERAL environmental factors), it is too naive to think one could completley stop it only by dietary changes, as real life experience demonstrates.

As a perfectly absurd example of how doctors have been wrongly influenced by the drug companies... about 8 years ago, I was a perfectly healthy 28 year old, in great shape, exercising daily, eating a balanced healthy diet full of antioxidants and quality nutrition, no smoking, and with no real risk factors for heart disease, and just because my cholesterol level has been consistently measured over 200 for my entire life, my doctor recommended I consider using a cholesterol lowering statin drug.

In Real Cause, Real Cure, my co-author and I reported a study from the University of Michigan that showed a cherry - enriched diet reduced four inflammatory factors by 50 % — reducing both local and systemic inflammation.

For example, KBs were recently reported to act as neuroprotective agents by raising ATP levels and reducing the production of reactive oxygen species in neurological tissues, 80 together with increased mitochondrial biogenesis, which may help to enhance the regulation of synaptic function.80 Moreover, the increased synthesis of polyunsaturated fatty acids stimulated by a KD may have a role in the regulation of neuronal membrane excitability: it has been demonstrated, for example, that polyunsaturated fatty acids modulate the excitability of neurons by blocking voltage-gated sodium channels.81 Another possibility is that by reducing glucose metabolism, ketogenic diets may activate anticonvulsant mechanisms, as has been reported in a rat model.82 In addition, caloric restriction per se has been suggested to exert neuroprotective effects, including improved mitochondrial function, decreased oxidative stress and apoptosis, and inhibition of proinflammatory mediators, such as the cytokines tumour necrosis factor - α and interleukins.83 Although promising data have been collected (see below), at the present time the real clinical benefits of ketogenic diets in most neurological diseases remain largely speculative and uncertain, with the significant exception of its use in the treatment of convulsion diseases.

This is one of the best fashion blogs for women by charlotte which is completely based on quality of real factors.

This is one of the best fashion blogs for women by charlotte which is completely based on quality of real factors.

The real estate's portal rating incorporated their users» preferences by calculating page views, frequency of searches, and other factors of users» activity in the second half of 2015, Redfin reported.

Lots of people are hampered by three main factors in real world dating: time, scale, and distance.

While the convenience offered by online dating services has certainly owed to the growth of this segment, the challenges faced by bisexuals in the real world has been an important factor too.