In the future, development of drugs that block CDHR3 potentially could help prevent and treat illnesses caused
by rhinovirus C.
The researchers at UNICAMP found a link between the SNP rs2107538 * CCL5 and bronchiolitis caused by RSV and RSV subtype A and a link between the SNP rs1060826 * NOS2 and bronchiolitis caused
by rhinovirus.
Furthermore, a genome - wide forward screen with Haplobank identified PLA2G16 as a host factor that is required for cytotoxicity
by rhinoviruses, which cause the common cold.
Not exact matches
Now, a new study led
by infectious disease researcher Dr. Sachiko Seo, formerly of Fred Hutch and now a physician at the National Cancer Research Center East in Chiba, Japan, and Boeckh and published last month in the journal Haematologica has found that like more «serious» viruses,
rhinovirus can cause pneumonia — and when it does, it can be deadly to those recovering from transplantation.
Researchers led
by James Gern, M.D., at the University of Wisconsin - Madison, discovered that CDHR3 recognizes and binds
rhinovirus C, enabling the virus to enter human cells.
The scientists identified CDHR3 as a potential candidate
by analyzing cells that either were or were not susceptible to
rhinovirus C infection.
Scientists funded
by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have identified a cellular receptor for
rhinovirus C, a cold - causing virus that is strongly associated with severe asthma attacks.
«
Rhinovirus C has been the «missing link» in explaining illness caused
by the common cold,» says Michael Rossmann, Hanley Distinguished Professor of Biological Science at Purdue and co-lead of the study with UW — Madison's Ann Palmenberg, professor of biochemistry and with the Institute for Molecular Virology.
Rhinovirus - induced inflammatory response was characterized
by apical and basal secretion of Eotaxin, IFN - λ1, CXCL10, IL - 6 and IL - 8.
Rhinovirus - induced inflammatory response was characterized
by apical and basal secretion of Eotaxin, IFN - λ1, CXCL10, IL
New research, conducted
by a team at Edinburgh Napier University and recently published in Peptides, has demonstrated that LL - 37 also has «potent antiviral activity towards Human
Rhinovirus» (HRV).
It's the most prevalent type of upper respiratory infection (URI) and is caused
by a virus (
rhinovirus).