Not exact matches
Scientists led
by John Kuwada, professor of molecular, cellular and developmental biology at the University of Michigan, and Hiromi Hirata of the National Institute of Genetics in Japan originally identified the gene in mutant zebrafish that exhibited
severe muscle weakness.
About SMA SMA is a
severe neuromuscular disease characterized
by the loss of motor neurons leading to progressive
muscle weakness and paralysis.
If the
muscle weakness is cause
by a
severe dysfunction, further manipulation or physiotherapeutic treatment will be needed to return the function of the
muscles.
Dogs will also experience gastric upset with symptoms of vomiting and diarrhea followed
by muscle weakness, respiratory difficulty, and CNS symptoms in
severe cases.
Muscle weakness and paralysis are the first signs but these can be followed
by seizures, difficulty breathing, and death in
severe cases.