Sentences with phrase «by single gene defects»
«Most PRAs, including the one in Phalenes and Papillons, are recessive and caused by single gene defects and small sample numbers can lead to breakthroughs.
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Almost immediately such familial genome sequencing proved its value, uncovering mutations responsible for diseases caused by defects in a single gene.
Allan - Herndon - Dudley syndrome is caused by defects to a single gene that controls the flow of thyroid hormone to the brain.
«Because individuals carrying a single mutant copy of a gene often mate with an individual with two normal copies of gene, defects can be hidden for a generation and then show up in the grandchildren,» Bier adds.
What's more, inherited diseases can arise from a problem with one gene (a simple example is sickle - cell anemia, a condition caused by defects in a single gene that makes the hemoglobin protein), or from interactions among a range of genetic variations as well as, frequently, environmental stresses.