Sentences with phrase «by statin»

It is thought that therapeutic doses of niacin may help close the gap on the residual risks left by statin drugs approaches.

The section on Alzheimer's is particularly compelling, and it points out the pitfalls in relying on previous studies done by the statin industry, where often those who have memory problems as side - effects of the statin drugs are excluded from the study, so that the results end up inappropriately biased in favor of statins.

30 %, similar to the reduction achieved by statin treatment....

I'm assuming you mean that cholesterol can't be too low...... as long as it is not caused by statin usage.

Many people are not able to fully bypass the metabolic blockages caused by statin drugs.

Lowering of LDL - C levels by statin therapy modestly increases the risk of type 2 diabetes, but it is unknown whether this effect is specific to statins.

The study looks at data on 26 side effects from a trial of approximately 10,000 patients and suggests that cases of muscle pain and weakness are unlikely to be directly caused by statins, but may instead be due to the so - called nocebo effect, where the expectation of side effects can make patients more likely to report them.

«The cancer cells need it for the high protein pathway activity and it can not be shut down by statins, like Lipitor, that lower serum cholesterol.»

Over the past few years, headlines from such studies have led to widespread dismissal of Dr. McCully's «Homocysteine Theory of Heart Disease» and renewed media focus on cholesterol, C - reactive protein and other possible culprits that can be treated by statins and other profitable drugs.

Over the past few years, headlines from such studies have led to widespread dismissal of Dr. McCully's «Homocysteine Theory of Heart Disease» and renewed media focus on cholesterol, c - reactive protein and other possible culprits that can be treated by statins and other profitable drugs.

This complex synthesis involves 37 steps and starts with a key enzyme known as HMG - CoA reductase (inhibited by statins, a class of cholesterol - lowering drugs).

WHAT TO AVOID TO HELP PREVENT ALZHEIMER»S DISEASE • STATIN DRUGS: Cholesterol is a vital part of the myelin sheath insulating neurons and assisting in propagation of nerve impulses; metabolites in the cholesterol biosynthesis pathway inhibited by statins are required to produce CoQ10 as well as functional GLUT4s.

Not exact matches

No, I take it the statin as prescibed by my physician.

I just replaced «statins» by «oral contraceptives» in your sentence.

Sounds like you are taking a statin purely by choice thinking that it may help you live longer by avoiding or delaying a heart event, but it certainly is not needed to keep you alive or out of pain today.

The findings suggest that fenofibrate therapy may be beneficial in the way the researchers hoped: by reducing cardiovascular events in patients with type 2 diabetes who take statins but still have especially high triglycerides levels and low HDL cholesterol levels.

After pooling the results of 27 trials involving 165,149 people, the meta - analysis reported that people are 21 percent less likely to suffer a serious vascular event such as a heart attack, stroke or bypass surgery after their cholesterol drops by the amount that might be expected after taking statins for a year than are similar people who do not take the pills.

«Trying something good for society has been my dream since boyhood, which has been realized at last by discovering statins,» he told us, «but my success as a scientist is far bigger than that I expected at the beginning of my work.»

Statins are highly effective for preventing heart attacks by reducing low - density lipoprotein or «bad» cholesterol.

(By including people who had vascular disease, the Lancet meta - analysis overestimated statins» benefits: a subgroup analysis reveals that among people who did not have vascular disease, statins only reduced the absolute risk of a cardiovascular event by 0.4 percent per yearBy including people who had vascular disease, the Lancet meta - analysis overestimated statins» benefits: a subgroup analysis reveals that among people who did not have vascular disease, statins only reduced the absolute risk of a cardiovascular event by 0.4 percent per yearby 0.4 percent per year.)

The statin skeptics worry that too little is understood about unintended consequences, especially for a drug taken for years on end by nearly one - quarter of adults past middle age, according to the Centers for Disease Control and Prevention's most recent data.

Just a couple of years ago, statin discoverer Akira Endo was tackling his elevated cholesterol by exercising more.

Guidelines released in 2013 by the American Heart Association and the American College of Cardiology say that people between the ages of 40 and 75 should take a statin if their risk of cardiovascular disease is 7.5 percent or higher over the next 10 years.

«Furthermore, risk of ischaemic heart disease can be reduced substantially by other lifestyle changes, as well as by drugs such as statins shown to be effective in primary prevention.»

In patients, Ridker found that statin drugs, widely known to prevent heart attacks by lowering cholesterol, lower CRP levels, too, suggesting they blunt inflammation — something Libby had seen in animals.

A study by investigators at Brigham and Women's Hospital (BWH) published this week in PLOS ONE identifies four factors that may account for sex differences in statin therapy among patients with coronary artery disease (CAD), pointing to interventions and additional research that will be needed to help overcome this sex disparity and reduce cardiovascular risk for women.

A statin drug commonly used to lower cholesterol is not effective in reducing the number and severity of flare ups from chronic obstructive pulmonary disease (COPD), according to the results of a large multicenter clinical trial designed and directed by Gerard J. Criner, MD, Director of Pulmonary and Critical Care Medicine at Temple University Hospital in Philadelphia, PA..

«Pancreatitis often caused by gallstones: Statins also increase risk, researchers say.»

For instance, note the NNT of 35 for statins (cholesterol - lowering drugs) in the primary prevention (avoiding a first - time event) of any bad thing (such as a heart attack), according to a table provided by the journal Bandolier, found at http://tinyurl.com/mrxngz.

Statins reduce the amount of cholesterol the liver produces by blocking the enzyme needed to make it.

The Mayo task force does not recommend in favor of or against the use of statins in patients with diabetes in whom the risk for heart attacks or stroke is low based on the calculator proposed by the ACC / AHA.

«For the reduction of heart disease and stroke risk, statins remain the most important drug - based strategy by far because of their demonstrated benefit and their good safety profile,» said Lloyd - Jones, who was a member of the task force that rewrote cholesterol treatment guidelines in 2013 for the American College of Cardiology and the American Heart Association.

Statins and other drugs can dampen that immune reaction; a 2012 trial in sepsis patients showed that atorvastatin reduced the risk of progressing to severe sepsis by 83 %.

The use of statins may not be associated with lowering risk for Parkinson's disease, according to a new study led by researchers at Penn State College of Medicine and National Institute of Environmental Health Sciences.

This clinical trial is the culmination of long - standing research led by Professor John Greenwood at the UCL Institute of Ophthalmology showing the potential therapeutic benefits of using statins to treat autoimmune diseases such as multiple sclerosis and uveitis.

This study was conducted by the same researchers who recently discovered that the use of cholesterol - lowering statins can improve survival in victims of ischemic stroke.

As a result of these findings, statins - which go by such brand names as Lipitor and Zocor - reap enormous profits for the firms selling them.

«Our results indicate that statins may have an important place in the prevention of bloodstream infection caused by S. aureus, which would hold important clinical and public health implications.

Twenty - three patients with dry AMD marked by soft lipid deposits in the outer retina were prescribed a high dose (80 mg) of atorvastatin, the generic name of the statin marketed as Lipitor ® and several generic equivalents.

To investigate whether individuals treated with statins experienced a decreased risk of bloodstream infection by S. aureus, researchers from the University Hospitals in Aalborg and Aarhus, Denmark and the University Hospital in Seville, Spain analyzed records of close to 30,000 people using Danish medical registries over a 12 - year period.

Nevertheless, our observations warrant confirmation in other settings and the biological mechanisms by which statin treatment may protect against this type of infection should be explored further,» explained lead investigator Jesper Smit, MD, PhD, of the Department of Clinical Microbiology, Department of Infectious Diseases, Aalborg University Hospital, and Department of Clinical Epidemiology, Aarhus University Hospital, Denmark.

The authors also discovered that statin stimulated the degradation of FGFR3 in mice by targeting the proteasomal pathway, offering new insight on the mechanism of action.

Golomb, a dark - haired whiz kid who graduated from the University of Southern California with highest honors at age 19, is an M.D. with a Ph.D. in biology and has been studying cholesterol and statins for more than a decade under research grants given by the Robert Wood Johnson Foundation and the Harry Frank Guggenheim Foundation.

These results suggest another mechanism by which statins may act to reduce the risk of AD.

• Reduced the risk for CHD events (including revascularization and unstable angina) by 19 %, compared with statin therapy alone.

A natural chemical that has been ignored by researchers largely because of the runaway success of the blockbuster statin drugs may in fact yield a rare twofer: a prime target for novel cholesterol -...

There were also no clear differences in the association between statin use and outcomes in analyses stratified by age older or younger than 55, 60, 65, or 70 years, with very similar estimates from 7 trials (eTable 6 in the Supplement).14, 19,20,26,29,31,35 None of the trials that enrolled patients older than 75 years18, 20,22,23,27,29 reported results in this subgroup.

The panel's decision was based almost entirely on the Jupiter trial, a study funded by Crestors maker, AstraZeneca, that compared a daily dose of Crestor to placebo in nearly 18,000 people who fit the description used by the panel (and who would not be eligible for a statin under the current guidelines).

Men who take statins or other medications to lower their cholesterol are also likely to see an improvement in their sexual function, according to a 2014 study by researchers at Rutgers University's Robert Wood Johnson Medical School.

«We believe that the new guidelines are not adequately supported by objective data, and that statins should not be recommended for this vastly expanded class of healthy Americans.