Sentences with phrase «by studying mouse»

Dr. Zhu began his investigation by studying a mouse that lacked Arid1a, the mouse version of a gene associated with some human cancers.

«We can't guess the biology of human brains and neurodevelopmental disorders just by studying mouse brains.»

Virgin and his team decided to explore this possibility by studying a mouse model of chronic norovirus infection.

And by studying mice lacking the gene for ERRγ (and therefore unable to make the ERRy molecule), the team observed that all brown fat cells resembled white cells in these mice.

Not exact matches

In a new study based on mice, scientists at Lancaster University found that a drug that goes after three diabetes - related targets «significantly reversed the memory deficit» in mice who got the drug, as measured by their performance in a maze test when compared to mice who didn't get the drug.

They've conducted studies in mice, which showed that the device was able to improve the results of the drug by twelve times.

A study at Harvard University found that alternate - day fasting among mice, «protected mice from strokes, Alzheimer's and Parkinson's disease, and consistently extended their life spans by 30 percent.»

A team led by David Sinclair of the University of New South Wales published a study in Cell, saying that they have actually reversed mice's aging process.

In a lab study, an extract of the leaves stopped the growth and progression of prostate cancer cells by up to 75 % in mice.

Another study published in 1999 by Anderson Laboratories found that lab mice exposed to various brands of disposable diapers experienced asthma - like symptoms, as well as eye, nose and throat irritation.

In a University of California, San Diego School of Medicine study published July 13 in the online journal Nature Neuroscience, a research team led by Takaki Komiyama, PhD, assistant professor of neurosciences and neurobiology, reports that in mouse models, the brain significantly changed its visual cortex operation modes by implementing top - down processes during learning.

A study by researchers at the University of Chicago Medicine shows that when mice that are genetically susceptible to developing inflammatory bowel disease (IBD) were given antibiotics during late pregnancy and the early nursing period, their offspring were more likely to develop an inflammatory condition of the colon that resembles human IBD.

«Our study shows that epigenetic drift, which is characterized by gains and losses in DNA methylation in the genome over time, occurs more rapidly in mice than in monkeys and more rapidly in monkeys than in humans,» explains Jean - Pierre Issa, MD, Director of the Fels Institute for Cancer Research at LKSOM, and senior investigator on the new study.

McGlinn will work within the supportive environment of ARMI, where 54 researchers are prying into the mysteries of vertebrate regeneration by studying sharks, mice, chickens, axolotls, and zebrafish.

On reanalysing data from the group's past studies, such as on pain sensitivity to hot water, the researchers found that mice tested by men showed lower baseline pain sensitivity than mice tested by women.The work indirectly demonstrates potential effects on nearly any kind of medical research, says Joseph Garner, who studies mouse behavior and well - being at Stanford University in California.

Researchers from Instituto de Medicina Molecular (iMM) Lisboa have created a chimera virus that allows the study of molecules to treat cancers caused by human herpes virus infection in mice models of disease.

Jiang said autism researchers worldwide could use the mouse model to study ways to compensate for the gene and improve symptoms in people with autism spectrum disorders and Phelan - McDermid Syndrome, a more profound developmental condition caused by mutations to SHANK3 and other genes in chromosome 22.

She latched onto the SCARB1 gene, inspired by a 2002 study in which MIT molecular biologist Monty Krieger found that mice engineered to lack that gene were more prone to heart attacks.

For decades, wildlife documentaries have promoted the idea that Komodo dragons owe their success as predators to toxic bacteria in their saliva — a claim bolstered by a 2002 study reporting deaths among lab mice injected with their saliva.

For this study the researchers targeted very specific types of GABA receptors to improve social behaviors with clonazepam, but the team also found that by using a different drug, they could target other GABA receptors and actually reduce the ability to socially interact in normal mice — underscoring that future medications would need to target very specific receptors so as not to diminish the drug's impacts.

In their study, Wright and PhD student Laura Castellani exercised mice by having them run until they reached exhaustion before giving them a dose of olanzapine.

In this study, Dr. Dimitriou monitored spindle signals in humans while they learned to control the position of a visual cursor by moving their hand (much like using a computer mouse).

They studied the bone metabolism at the cellular level using advanced imaging and computational techniques, which allowed them to identify 142 metabolites that were significantly altered by more than 1.5 times in the diabetic mice.

The study, sponsored by the Office of Naval Research (ONR) Global, involved the use of Transcranial Direct Current Stimulation, or tDCS, on the mice.

Mice with colon cancer studied by HQ Han and colleagues at Amgen Research in California stopped eating, and lost 20 per cent of their body weight in three weeks.

Since then, Pereira - Smith's team has moved into using genetic techniques in mice to study whether and how senescence is regulated by MORF4 and related genes.

In the study, led by post-doctoral fellow Long N. Nguyen of Duke - NUS, researchers found that mice without the Mfsd2a transporter had brains a third smaller than those with the transporter, and exhibited memory and learning deficits and high levels of anxiety.

The study found that a mother mouse can pass along to her offspring a susceptibility to intestinal disorders, such as inflammatory bowel disease, by way of a gut - residing bacterium called Sutterella, the researchers reported in the journal Nature on Feb. 16.

I wrote recently about a mouse study that found a substance produced by toned muscles could protect the brain against a form of stress - induced depression.

A study in this issue of JCI Insight demonstrates that mice lacking the proinflammatory signaling molecule TAK1 are protected from obesity and insulin resistance induced by a high fat diet.

In the study, published online today by Science Translational Medicine, researchers removed breast tumors from mice and placed biodegradable gels containing an immune - stimulating drug in the resulting empty space.

The new study indicates that such infections in the mice cause the number of tuft cells to increase by five - to tenfold, leading the norovirus to replicate more efficiently.

Marta Monteiro and colleagues at the University of Lisbon, Portugal, studied mice protected from the animal equivalent of multiple sclerosis by natural killer T - cells (NKT), a class of white blood cell which helps to control the immune system.

In Lausanne, the researchers carried out a detailed study of the genome and the «phenome» (the set of all phenotypes or clinical features) of a family of mice composed by 183 members.

A new study by University of Maryland School of Medicine researchers has found that in mice, adjusting levels of a compound called kynurenic acid can have significant effects on schizophrenia - like behavior.

A study published by Cell Press October 16th in Cell now reveals that gut microbes in mice and humans have circadian rhythms that are controlled by the biological clock of the host in which they reside.

It was known from previous studies that these mice have an overactive metabolism, caused by the energy needed to generate heat from brown fat, which might seem contradictory given their impaired thyroid hormone function.

Guo and his collaborators continue their studies by establishing additional mouse models of leukemia that have been transplanted with patient cells of relapsed and refractory disease.

In the Cell study, Dr. Massagué, with Fellow Manuel Valiente, PhD, and other team members, found that in mouse models of breast and lung cancer — two tumor types that often spread to the brain — many cancer cells that enter the brain are killed by astrocytes.

The muscle decline was completely reversed by feeding the mice a form of vitamin B3, called nicotinamide riboside (NR), obtained from natural products company ChromaDex, a study collaborator.

The idea for Smith's study was inspired by the work of co-author Alena Savonenko, M.D., Ph.D., associate professor of pathology, and her colleagues who showed that loss of serotonin neurons was associated with more protein clumps, or amyloid, in mouse brain.

In fact, both of the studies found that when adenosine was turned on in mouse tissue by other mechanisms, the pain response was equal to or better than the response generated by acupuncture.

Scanziani and his colleagues sought to understand the origins of this adaptive plasticity by studying the eye movements in mice before and after disabling their vestibular ocular reflex.

In this study, we investigated the importance of oxygen by analyzing mice with a mutation that makes their bone cells behave as if they were deprived of oxygen.»

Mice transplanted with cells grown from a patient suffering from Huntington's disease (HD) develop the clinical features and brain pathology of that patient, suggests a study published in the latest issue of Acta Neuropathologica by CHA University in Korea, in collaboration with researchers at Université Laval in Québec City, Canada.

An additional study, currently available at bioRxiv, led by the researchers from the CRG and Cold Spring Harbour Laboratory, highlights the fact that a substantial part of human and mice genes have maintained an essentially constant expression throughout evolution, in tissues and various organs.

Senior author Madhav Dhodapkar, M.D., the Arthur H. and Isabel Bunker Professor of Medicine and Immunobiology, and chief of Hematology, said the study, using tissue and blood samples from humans and mice, shows that chronic stimulation of the immune system by lipids made in the context of inflammation underlies the origins of at least a third of all myeloma cases.

Studies involving rabbits and larger mammals, for example, are overseen chiefly by the U.S. Department of Agriculture (USDA) in Washington, D.C. Federally funded studies of rats, mice, and birds are subject to different rules and a different overseer, the National Institutes of Health (NIH) in Bethesda, MaStudies involving rabbits and larger mammals, for example, are overseen chiefly by the U.S. Department of Agriculture (USDA) in Washington, D.C. Federally funded studies of rats, mice, and birds are subject to different rules and a different overseer, the National Institutes of Health (NIH) in Bethesda, Mastudies of rats, mice, and birds are subject to different rules and a different overseer, the National Institutes of Health (NIH) in Bethesda, Maryland.

This is the finding of a study in both mice and human patients led by researchers at NYU Langone Medical Center and published online June 9 in the journal Cell.

The study also found that a lack of exposure in early life could not be compensated for by introducing the GF mice to a broader range of microbes in adulthood.