This conclusion is provocative because the dogma has been that a memory is instead stored
by synaptic strength,» says Susumu Tonegawa, the Picower Professor of Biology and Neuroscience, the director of the RIKEN - MIT Center for Neural Circuit Genetics at the Picower Institute for Learning and Memory, and the study's senior author.
Not exact matches
These properties, which are believed to be important for the induction of long - term changes in
synaptic strength, are imparted
by asparagine residues in a putative channel - forming segment of the protein, transmembrane 2 (TM2).
Geoff Hinton, a leading neural networking theorist, argues the hardware is useless without the proper «learning algorithm» spelling out which factors change the
strength of the
synaptic connections and
by how much.
With the combined use of genetics and pharmacology, the investigators altered the production of proteins controlled
by eIF2α in adult mice, essentially converting them into adolescents
by making them more susceptible to cocaine - induced changes in
synaptic strength and behavior.
Based on evidence from electrophysiological studies showing that both
synaptic plasticity and
strength of inputs to hippocampal region CA1 vary systematically with ongoing theta oscillations (Hyman et al., 2003; Brankack et al., 1993), it has been suggested that the theta rhythm functions to separate periods of encoding of current sensory stimuli and retrieval of episodic memory cued
by current stimuli so as to avoid interference that would occur if encoding and retrieval were simultaneous.