Sentences with phrase «by thalidomide»
In other work, Henning Moelle has been acting as international lead counsel for the pharmaceutical company Grünenthal in product liability claims for alleged birth defects caused by thalidomide.
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When asked by Nature for relevant studies, the plaintiffs» lawyers at Hagens Berman Sobol Shapiro in Seattle, Washington, pointed to work showing one - sided limb defects in chick embryos exposed to thalidomide and thalidomide analogues (C. Therapontos et al..
The lawsuit, filed in a Philadelphia court on 25 October, asserts that before thalidomide was pulled from markets around the world, samples were doled out to more than 1,200 physicians in the United States by three companies whose legal liabilities are now the property of Sanofi - Aventis US, based in Bridgewater, New Jersey.
By November 1961, thalidomide was taken off the market in Germany, and other countries soon followed.
When scientists tried to clarify the fatal effects the drug had when taken by pregnant women, they found that only (S)- thalidomide caused birth defects, whereas (R)- thalidomide had the desired calming and anti-nausea effects.
They discovered that although high doses of thalidomide stop angiogenesis, lower doses actually fortify the blood vessels by spurring cell growth.
It is far from clear that thalidomide's terrible effects would have been detected even by today's animal testing.
It went on sale under many names in more than 40 countries, but is best known by a brand name that can still strike a chill in those born in the late 1950s: thalidomide.
While too late to help those whose lives were blighted by the drug during pregnancy, this finding could help rehabilitate thalidomide, which is effective against several serious conditions, including multiple myeloma, a form of cancer.
Like thalidomide and Accutane, statin drugs are a class X drug with regard to pregnancy, meaning they are contraindicated and should NOT be taken by pregnant women.
Representing Grünenthal on the major product liability case involving a claim for damages in over $ 204m filed by the Spanish Association AVITE (Asociación de Víctimas de la Talidomida en España) representing 184 victims of thalidomide, for alleged damages caused in the 1960's for the administration of thalidomide.