Sentences with phrase «by the insulin biomarker»

The primary efficacy measurement in the trial will be the clinically relevant production of insulin, as measured by the insulin biomarker C - peptide, in a patient population that has little to no ability to produce endogenous insulin upon enrollment.

The primary efficacy measurement in the trial will be the clinically relevant production of insulin, as measured by the insulin biomarker C - peptide, in a patient population that has little to no ability to produce endogenous insulin at the time of enrollment.

Not exact matches

In particular, the PTPRF gene, which is known to suppress intracellular signals that are usually triggered by insulin binding to its receptor on the cell surface, may serve as a biomarker linking insulin resistance with insufficient milk supply.

We perform the transient silencing of several genes in parallel by RNA interference in order to identify those able to modify two types of DM1 biomarkers expressed by one DM1 - hES cell line progeny: the pathological intranuclear ribonucleoaggregates called foci and the insulin receptor splicing defect.