L - tyrosine is the substrate for the production of L - Dopa
by tyrosine hydroxylase, allowing survival of dopamine signaling neurons.
The ring of tyrosine is then hydroxylated to dihydroxyphenylalanine (DOPA)
by tyrosine hydroxylase.
Not exact matches
Accompanying this, vaccination with AFF 1 prevented 66 % of the loss of
tyrosine hydroxylase - staining (TH + — likely dopaminergic) neurons suffered
by vehicle - treated mThy1 - AS mice (all Figure 1).
Koch discusses the enzyme deficiency: «Phenylketonuria (PKU) is caused
by an autosomal recessive defect in the enzyme phenylalanine
hydroxylase, which is required for converting phenylalanine to
tyrosine.