Sentences with phrase «by xanthine»
needed by xanthine oxidase enzyme, which oxidises purines into uric acid, a protective plasma antioxidant assisting in neutralizing radicals, including those formed during detoxication
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Martins found the answer by extracting two molecules from the meteorite: uracil, a nucleobase found in RNA, and xanthine, an intermediate in the synthesis of DNA and RNA.
Generation of the superoxide was greatly affected by phytic acid; the IC50 was about 6 mM, indicating that the superoxide generating domain of xanthine oxidase is more sensitive to phytic acid.
«Inhibition of xanthine oxidase by phytic acid and its antioxidative action.»
Evidence of oxidative stress was found in the mucosa of the small intestine of drug - treated rats, as indicated by significantly increased activity of xanthine oxidase (P < 0.001) and myeloperoxidase (P < 0.001), with corresponding decreases in the levels of several free radical scavenging enzymes and alpha - tocopherol (P < 0.001 in all cases).