Not exact matches
These risks and uncertainties include, among others: the unfavorable outcome of litigation, including
so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted
by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial
obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization
by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made
by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.
Back in 2010 it paid $ 550 million to settle charges brought
by the Securities and Exchange Commission that it mislead investors into buying a
so - called synthetic collateralized debt
obligation named Abacus, which was made up of a bundle of financial instruments tied to subprime mortgage bonds, many of which plummeted in value shortly after the deal was sold.
in the case of our directors, officers, and security holders, (i) the receipt
by the locked - up party from us of shares of Class A common stock or Class B common stock upon (A) the exercise or settlement of stock options or RSUs granted under a stock incentive plan or other equity award plan described in this prospectus or (B) the exercise of warrants outstanding and which are described in this prospectus, or (ii) the transfer of shares of Class A common stock, Class B common stock, or any securities convertible into Class A common stock or Class B common stock upon a vesting or settlement event of our securities or upon the exercise of options or warrants to purchase our securities on a «cashless» or «net exercise» basis to the extent permitted
by the instruments representing such options or warrants (and any transfer to us necessary to generate such amount of cash needed for the payment of taxes, including estimated taxes, due as a result of such vesting or exercise whether
by means of a «net settlement» or otherwise)
so long as such «cashless exercise» or «net exercise» is effected solely
by the surrender of outstanding stock options or warrants (or the Class A common stock or Class B common stock issuable upon the exercise thereof) to us and our cancellation of all or a portion thereof to pay the exercise price or withholding tax and remittance
obligations, provided that in the case of (i), the shares received upon such exercise or settlement are subject to the restrictions set forth above, and provided further that in the case of (ii), any filings under Section 16 (a) of the Exchange Act, or any other public filing or disclosure of such transfer
by or on behalf of the locked - up party, shall clearly indicate in the footnotes thereto that such transfer of shares or securities was solely to us pursuant to the circumstances described in this bullet point;
Instead, they prefer to trust government to do
so, even if only
by borrowing money, for which task they pledge the
obligations of their children and their grandchildren.
Such a view would not be quite
so absurd as might at first appear: the divine temporal evaluations would seem to be no more arbitrary than those of the constitution of the primordial nature in Whitehead's view; and the divine subjective aim toward the maximum of value intensity, together with the property of everlastingness and the Categoreal
Obligations (constituted
by the primordial nature) of Subjective Unity and Subjective Harmony, would seem sufficient to insure the mutual coherence of the growing series of divine temporal evaluations.
Then there are the Bad Attitudes of the immature in faith: I have a hard time accepting myself; I feel overwhelmed
by all the responsibilities and
obligations I have; My life is filled with stress and anxiety; I tend to be critical of other people; I do not want churches getting involved in political issues; I do not understand how a loving God can allow
so much pain and suffering in the world.
Society must thus be secured against the intrusions of the Good, or of God,
so that its citizens may determine their own lives
by the choices they make from a universe of morally indifferent but variably desirable ends, unencumbered
by any prior grammar of
obligation or value (in America, we call this the «wall of separation»).
The evil of the world is that those elements which are translucent
so far as transmission is concerned, in themselves are of slight weight; and that those elements with individual weight,
by their discord, impose upon vivid immediacy the
obligation that it fade into night.
Democracy itself is not possible unless the constituted political process is in large or, at least, tolerable measure successful,
so that governance fulfills its moral
obligations by pursuing justice as general emancipation.
You can't be talked out of that — and Panikker's point is that no one should try: our opportunity and
obligation is to speak and to listen,
so that heart will speak to heart across and
by means of our differences.
Work was carried out largely through a system of slaves,
so that the privilege of play and the
obligation of work were mutually exclusive social functions performed
by two distinct groups in society.
Most people feel the
obligation to «be in church» on Sunday and most feel they are fulfilling their Christian duty
by doing
so.
While agreeing that Campus Crusade had no
obligation to pay film royalties to him, Heyman said ruefully: «Had [Campus Crusade] paid a one - cent royalty for everyone they claim to have led to Christ
by showing the Jesus film, we would have been able to translate Acts of the Apostles onto film and we would have had a much more «Christian» world than we do — but they did not and
so we could not.»
Systems and principles of justice are the servants and instruments of the spirit of brotherhood in
so far as they extend the sense of
obligation towards the other, (a) from an immediately felt
obligation, prompted
by obvious need, to a continued
obligation expressed in fixed principles of mutual support; (b) from a simple relation of the self and one «other» to the complex relations of the self and the «others»; and (c) finally from the
obligations... which the community defines from its more impartial perspective.5
So in spite of my trepidation, and in awe of tradition, and knowing that this gives an impression of audacity when what I feel is rather an
obligation that I can not avoid, I am impelled
by my understanding (such as I am capable of) to raise this challenge.
Problem is that some church's have entered into the business world,
by doing
so they have
obligations to their employees and if they want to remain in the business world they have to live up to those
obligations.
It is a celebration of the present experience of God
by the people (a majority of whom are Dalits and Adivasis) and not
so much an
obligation to stage the eternal experience of the God of the ecclesiastical fathers.
In fact, all my anxieties run in the opposite direction: that, in order to affirm the uniqueness of humanity within organic nature, as well as the unique moral
obligations it entails, we will reject all evidence of intentionality, reason, or affection in animals as something only apparently purposive, doing
so by reference to the most egregiously vapid of philosophical naturalism's mystifications — «instinct» — and thereby opening the way to a mechanistic narrative that, as we have learned from an incessant torrent of biological and bioethical theory in recent decades, can be extended to human behavior as well.
The moral implications of the covenant did not readily take on the character of universal
obligation and were never
so conceived
by the rank and file of the people.
That is to say, no moral
obligations were recognized toward Amalekites,
so that while within the tribal group ideals of fair play and humane dealing might rise to great heights, this vertical reach of moral responsibility was not matched
by its horizontal extension.
In such circumstances, is it not clear that my sense of
obligation continues to attach itself to the path that would be dictated
by reflection, whether or not its doing
so determines the final decision?
Also I was taught that when you commit to something - whether its a hobby, a job, helping a friend move, or whatever that you stick with it or don't commit,
so this shouldn't be looked upon
by the staff as some sort of annoying
obligation.
We believe that there is an
obligation to foster awareness and understanding
so that children, adolescents and adults affected
by selective mutism will have access to the help they need to overcome their anxiety and reach their full potential of personal growth and participation in society.
(if I take in consideration the comment made
by phoog: How can the French government act (in any way) on a particular religion (and
so, the people practicing it) while it has an
obligation of neutrality towards its citizen?)
On 29 August 2009, the convention was ratified
by the standing Committee of the National People's Congress of China, China's top legislative body, which indicates that China is under legal
obligation to internalize the norms stipulated in the FCTC
so as to effectively control tobacco use.
In the treaty, Japan does accept the
obligations of the United Nations Charter with respect to pacific settlement of disputes, but
so do all the member states of the United Nations,
so Japan is not any more restricted
by this provision than any other UN member state is.
The logical extension is that if a contracting party does not do
so, they must consider themselves still members and therefore bound
by all the ensuing
obligations.
It has a permanent tax base,
so in theory it can time - shift its debt
obligations indefinitely - without even reducing the bond - rating
by simply shifting the ratio of revenue spent on debt servicing versus every other
obligation.
Those in civil partnerships can choose to convert their relationships to marriage, via a procedure expected to be in place
by the end of the year, but are under no
obligation to do
so.
Some experts say that
by withholding
so much information in the Cetero case the FDA failed to meet its
obligations to the public.
In addition, the guide states, researchers have the «
obligation to keep clear, accurate, and secure records of their research data and of corresponding primary material
so that their work can be verified or replicated
by others.»
Debtors attempt to fulfil their
obligations to the IMF
by exporting natural resources such as minerals, timber, meat, fish, tropical crops and
so on.
Yet the pace of HIV vaccine research is now growing
so swiftly that the scientific goal of conducting and completing a clinical trial may be threatened
by a higher ethical
obligation — to inform those taking part in the study that the original scientific basis for the research may have been modified
by later work.
If you do
so cancel, any payments made
by you will be refunded within 21 days after notice of cancellation is delivered, and any evidence of any indebtedness executed
by you will be cancelled
by us and arrangements will be made to relieve you of any further
obligation to pay the same.
The expense of postage and the time it took students to write either online or
by snail mail became
so cumbersome that we were not able to fulfill our
obligation to this project.»
To do
so we might do well to consider Facing History's idea of the «universe of
obligation» defined
by Helen Fein as «the circle of individuals and groups toward whom
obligations are owed, to whom rules apply, and whose injuries call for amends.»
Teachers look for a balance between spending enough time on topics
so that students can thoughtfully and thoroughly understand concepts, and retain this understanding for the long - term, with
obligations to teach many learning outcomes deemed important
by the BC Ministry of Education.
Yet decades of good intentions always have yielded to the understandable
obligation to make a profit, and
so the Mustang has always been undone
by the limited performance that could be delivered at an affordable price.
So if you're like me and have projects outside the scope of the agent / editor contractual or personal
obligations you have, then
by all means, it seems to make sense to try another revenue stream.
If you don't feel the book is worth reading and can't recommend it, gracefully bow out
by telling the author it's not your thing, or you're too busy (you can give pointers on how to improve if you want, but you're under no
obligation to do
so.)
So, unless something truly catastrophic happens (like the US government defaulting on its bonds) or people in the company break the regulations (which would invovle all kinds of serious crimes and require complicity or complete failure of the auditors), your premiums and the contractual
obligation to you would still be there, and would be absorbed
by a different insurance company that takes over the defunct company's business.
So their rights and
obligations are just a historical
by - product and not their defining feature.
The quote is free and carries no
obligation,
so what do you have to lose
by contacting us today?
After accounting for the cost of raising your kids as well as their future college expenses, you have about $ 1.9 million in financial
obligations, meaning that you ideally need that amount minus your liquid assets covered
by life insurance —
so about $ 1.8 million in coverage.
And to see whether your pension benefit is covered
by the PBGC and, if
so, how much of your benefit this federal government agency would pay should your company default on its pension
obligations, you should go to the Pension Benefit Guaranty Corp's site.
-- Any consumer may cancel any contract with any credit repair organization without penalty or
obligation by notifying the credit repair organization of the consumer's intention to do
so at any time before midnight of the 3rd business day which begins after the date on which the contract or agreement between the consumer and the credit repair organization is executed or would, but for this subsection, become enforceable against the parties.
General
obligation bonds tracked in the S&P Municipal Bond Illinois G.O. Index have also seen volatility as they have recovered
by returning 8.34 %
so far.
Typically you're expecting the stock to decline in value
so you can make a profit
by using shares bought later at a lower price to meet your
obligation to restore the shares you borrowed when you made the short sale.
That's the problem with signing reaffirmation agreements: there's a possibility that
by doing
so, clients will be creating extremely expensive
obligations for something that almost every adult needs: a functional car.
By accepting and receiving a closed school loan discharge, you have no further
obligation to repay the loan, and you will receive a reimbursement of payments made voluntarily or through forced collection, and the discharge will be reported to credit bureaus
so as to delete any adverse credit history associated with the loan.